MA126017

Alpha-Smooth Muscle Actin Monoclonal Antibody (0.N.5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA126017-Each-of-1 In Stock ₹ 53,004.42

MA126017 - Each of 1

₹ 53,004.42

In Stock

Quantity

1

Base Price: ₹ 53,004.42

GST (18%): ₹ 9,540.796

Total Price: ₹ 62,545.216

Antigen

Alpha-Smooth Muscle Actin

Classification

Monoclonal

Concentration

0.04 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P62736, P62737, P62738

Gene Symbols

ACTA2

Immunogen

Synthetic peptide corresponding to the N-terminal residues M(1) C E E E D S T A L(10) of alpha smooth muscle Actin.

Quantity

250 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

0.N.5

Conjugate

Unconjugated

Gene

ACTA2

Gene Alias

0610041G09Rik; AAT6; ACT-4; acta2; acta2.L; acta2.S; actin; Actin Alpha 2 Smooth Muscle Aorta; actin alpha 2, smooth muscle; Actin Vascular Smooth Muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha 2, smooth muscle, aorta L homeolog; actin, alpha 2, smooth muscle, aorta S homeolog; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha actin 2; Alpha Cardiac Actin; alpha smooth muscle actin; alpha-actin; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-SM-actin; alpha-smooth muscle actin; Aortic Smooth Muscle; ASMA; a-sma; cell growth-inhibiting gene 46 protein; GIG46; Growth Inhibiting Gene 46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, aortic smooth muscle; mymy5; SM actin; sma; SMactin; sm-actin; SMalphaA; smooth muscle; smooth muscle alpha-actin; vascular smooth muscle alpha-actin; wu:fb63d03; XELAEV_18034370mg

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

11475, 59, 81633

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • It does not react with fibroblasts, striated muscle, or myocardium
  • Positive control of smooth muscle or leiomyosarcoma suggested
  • Smooth Muscle Actin belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity
  • Alpha, beta and gamma actin isoforms have been identified, with alpha actin being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility
  • In particular, smooth muscle actin is an alpha actin that is found in skeletal muscle
  • Actin exists as a ubiquitous protein involved with filament formation that make up large portions of the cytoskeleton
  • Actin filaments interact with myosin to assist in muscle contraction as well as aiding in cell motility and cytokinesis
  • Smooth muscle actin is found on smooth muscle vessel walls, gut wall, myometrium, myoepithelial cells in breast and salivary glands
  • Defects in the smooth muscle actin gene cause aortic aneurysm familial thoracic type 6
  • Actin isoforms differ slightly in their N-terminus and the sequences of each are perfectly conserved in higher vertebrates
  • Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells
  • In addition, it has also been shown that smooth muscle actin appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases
  • Multiple alternatively spliced variants of smooth muscle actin have been identified.

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Img

Thermo Scientific

MA126017

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Antigen:
Alpha-Smooth Muscle Actin

Classification:
Monoclonal

Concentration:
0.04 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P62736, P62737, P62738

Gene Symbols:
ACTA2

Immunogen:
Synthetic peptide corresponding to the N-terminal residues M(1) C E E E D S T A L(10) of alpha smooth muscle Actin.

Quantity:
250 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
0.N.5

Conjugate:
Unconjugated

Gene:
ACTA2

Gene Alias:
0610041G09Rik; AAT6; ACT-4; acta2; acta2.L; acta2.S; actin; Actin Alpha 2 Smooth Muscle Aorta; actin alpha 2, smooth muscle; Actin Vascular Smooth Muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha 2, smooth muscle, aorta L homeolog; actin, alpha 2, smooth muscle, aorta S homeolog; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha actin 2; Alpha Cardiac Actin; alpha smooth muscle actin; alpha-actin; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-SM-actin; alpha-smooth muscle actin; Aortic Smooth Muscle; ASMA; a-sma; cell growth-inhibiting gene 46 protein; GIG46; Growth Inhibiting Gene 46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, aortic smooth muscle; mymy5; SM actin; sma; SMactin; sm-actin; SMalphaA; smooth muscle; smooth muscle alpha-actin; vascular smooth muscle alpha-actin; wu:fb63d03; XELAEV_18034370mg

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11475, 59, 81633

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA126058

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Antigen:
TGF beta-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.01M PBS with no preservative; pH 7.2

Gene Accession No.:
P01137

Gene Symbols:
Tgfb1

Immunogen:
TGF beta from human platelets.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
2C5

Conjugate:
Unconjugated

Gene:
Tgfb1

Gene Alias:
CED; cytokine; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGF b; TGF b 1; TGF beta; tgf beta 1; tgf beta1; TGF beta-1; TGF beta-1 protein; TGF β; TGF β 1; TGF β1; Tgfb; TGFB1; TGF-B1; Tgfb-1; TGFbeta; TGF-beta 1; TGF-beta 1 protein; TGFbeta1; TGF-beta1; TGF-beta-1; TGFβ1; Transforming growth factor; transforming growth factor b1; transforming growth factor beta; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor β1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta I; transforming growth factor-beta-1; transforming growth factor-beta-1 precursor; unnamed protein product

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7040

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA126180

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Antigen:
Cardiac Myosin Heavy Chain

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
A2AQP0, A7E2Y1, P02563, P02564, P04460, P04461, P12883, P13533, P49824, P79293, Q02566, Q91Z83, Q9BE39

Gene Symbols:
LOC100736765, MYH6, Myh7, Myh7b

Immunogen:
Purified, full length, native human protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Human, Mouse, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Clone:
3-48

Conjugate:
Unconjugated

Gene:
MYH6

Gene Alias:
A830009F23Rik; AA517445; alpha cardiac MHC; alpha myosin; alpha-cardiac myosin heavy chain; alpha-MHC; alpha-myosin; alpha-myosin heavy chain; alpha-myosin heavy chain subfragment 2 exon; antigen MLAA-21; ASD3; beta cardiac myosin heavy chain; beta myosin heavy chain; beta-MHC; beta-myosin; beta-myosin heavy chain; B-MHC; cardiac muscle myosin heavy chain 7 beta; cardiac myosin heavy chain alpha isoform; cardiac myosin heavy chain beta isoform; cardiomyopathy, hypertrophic 1; CMD1EE; CMD1S; CMH1; CMH14; KIAA1512; LOC100736765; LOW QUALITY PROTEIN: myosin-6; LOW QUALITY PROTEIN: myosin-7B; MHC14; MPD1; Myh14; MYH6; MYH7; Myh7b; MYH-beta/slow; MYHC; Myhca; Myhc-a; MyHC-alpha; MYHCB; Myhc-b; MyHC-beta; MyHC-I; MyHC-slow; myopathy, distal 1; myosin alpha heavy chain; Myosin cardiac muscle beta chain; myosin heavy chain; myosin heavy chain 6; Myosin heavy chain 7; myosin heavy chain 7B; myosin heavy chain 7B, cardiac muscle beta isoform; myosin heavy chain polypeptide 6 cardiac muscle adult; myosin heavy chain polypeptide 7 cardiac muscle fetal; myosin heavy chain slow; myosin heavy chain slow isoform; myosin heavy chain slow type 1 (beta cardiac); myosin heavy chain, cardiac; myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha); myosin heavy chain, cardiac muscle beta isoform; myosin heavy chain, cardiac muscle, adult; myosin heavy chain, cardiac muscle, fetal; myosin heavy chain, polypeptide 6, cardiac muscle, alpha; myosin heavy chain, polypeptide 7; myosin, heavy chain 6, cardiac muscle, alpha; myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); myosin, heavy chain 7, cardiac muscle, beta; myosin, heavy chain 7B, cardiac muscle, beta; myosin, heavy polypeptide 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); myosin, heavy polypeptide 7, cardiac muscle, beta; myosin, heavy polypeptide 7B, cardiac muscle, beta; myosin-6; Myosin-7; myosin-7B; rhabdomyosarcoma antigen MU-RMS-40.7A; slow A MYH14; slow myosin heavy chain; slow myosin heavy chain-beta; slow type myosin heavy chain; SPMD; SPMM; SSS3; type slow/beta myosin heavy chain; U937-associated antigen; Unknown (protein for IMAGE:7985957)

Host Species:
Mouse

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
100101566, 100125987, 100157870, 100296004, 100356178, 100685644, 100736765, 140781, 17888, 282714, 29556, 29557, 311570, 396860, 403807, 4624, 4625, 477206, 521764, 57644, 668940

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA126249

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Antigen:
POLR2A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
P08775, P24928

Gene Symbols:
POLR2A

Immunogen:
Purified wheat germ RNA polymerase II.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Plant

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Inhibition Assays, Western Blot

Clone:
8WG16

Conjugate:
Unconjugated

Gene:
POLR2A

Gene Alias:
220kDa; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directeced RNA polymerase II polypeptide A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; N0825; Pol II S2p; POL2; POLR2; Polr2a; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; RPB1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8; YNL262W

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20020, 5430

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid