MA106110

Alpha-Smooth Muscle Actin Monoclonal Antibody (1A4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA106110-Each-of-1 In Stock ₹ 52,362.72

MA106110 - Each of 1

₹ 52,362.72

In Stock

Quantity

1

Base Price: ₹ 52,362.72

GST (18%): ₹ 9,425.29

Total Price: ₹ 61,788.01

Antigen

Alpha-Smooth Muscle Actin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P08023, P62736, P62737, P62738

Gene Symbols

ACTA2, acta2.L

Immunogen

Peptide corresponding to residues E(1) E E D S T A L V C(10) of alpha-smooth muscle actin with an acetylated n-terminus coupled to KLH.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Avian, Chicken, Goat, Human, Mouse, Non-human Primate, Ovine, Porcine, Rat, X. laevis

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunomicroscopy, Western Blot

Clone

1A4

Conjugate

Unconjugated

Gene

ACTA2

Gene Alias

0610041G09Rik; AAT6; ACT-4; acta2; acta2.L; acta2.S; actin; Actin Alpha 2 Smooth Muscle Aorta; actin alpha 2, smooth muscle; Actin Vascular Smooth Muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha 2, smooth muscle, aorta L homeolog; actin, alpha 2, smooth muscle, aorta S homeolog; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha actin 2; Alpha Cardiac Actin; alpha smooth muscle actin; alpha-actin; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-SM-actin; alpha-smooth muscle actin; Aortic Smooth Muscle; ASMA; a-sma; cell growth-inhibiting gene 46 protein; GIG46; Growth Inhibiting Gene 46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, aortic smooth muscle; mymy5; SM actin; sma; SMactin; sm-actin; SMalphaA; smooth muscle; smooth muscle alpha-actin; vascular smooth muscle alpha-actin; wu:fb63d03; XELAEV_18034370mg

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

101121051, 102191486, 11475, 423787, 431847, 59, 733615, 81633

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Thermo Scientific

MA126017

--

Img

Thermo Scientific

MA5157391MG

--

Img

Thermo Scientific

MA191399

--

Img

Thermo Scientific

MA1140A488

--

Img

Thermo Scientific

MA1140A555

--

Img

Thermo Scientific

MA515739D68

--

Img

Thermo Scientific

MA515739HRP

--

Img

Thermo Scientific

MA515739D65

--

Description

  • MA1-06110 detects a-smooth muscle actin (a-SM1) in human, rat, goat, porcine, non-human primate, quail, ovine, xenopus, monkey and chicken samples
  • Since the epitope recognized by MA1-06110 is highly conserved, it can also cross-react with protochordates, lower craniates and mammals other than those specifically listed
  • MA1-06110 has sucessfully been used in immunocytochemistry, immunomicroscopy, immunohistochemistry, and Western blotting procedures
  • The MA1-06110 immunogen is a peptide corresponding to residues E(1) E E D S T A L V C(10) of alpha-smooth muscle actin with an acetylated n-terminus coupled to KLH
  • MA1-06110 specifically recognizes the epitope Ac-EEED on alpha-smooth muscle actin
  • Smooth Muscle Actin belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity
  • Alpha, beta and gamma actin isoforms have been identified, with alpha actin being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility
  • In particular, smooth muscle actin is an alpha actin that is found in skeletal muscle
  • Actin exists as a ubiquitous protein involved with filament formation that make up large portions of the cytoskeleton
  • Actin filaments interact with myosin to assist in muscle contraction as well as aiding in cell motility and cytokinesis
  • Smooth muscle actin is found on smooth muscle vessel walls, gut wall, myometrium, myoepithelial cells in breast and salivary glands
  • Defects in the smooth muscle actin gene cause aortic aneurysm familial thoracic type 6
  • Actin isoforms differ slightly in their N-terminus and the sequences of each are perfectly conserved in higher vertebrates
  • Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells
  • In addition, it has also been shown that smooth muscle actin appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases
  • Multiple alternatively spliced variants of smooth muscle actin have been identified.

Compare Similar Items

Show Difference

Img

Thermo Scientific

MA106110

--


Antigen:
Alpha-Smooth Muscle Actin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P08023, P62736, P62737, P62738

Gene Symbols:
ACTA2, acta2.L

Immunogen:
Peptide corresponding to residues E(1) E E D S T A L V C(10) of alpha-smooth muscle actin with an acetylated n-terminus coupled to KLH.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Avian, Chicken, Goat, Human, Mouse, Non-human Primate, Ovine, Porcine, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunomicroscopy, Western Blot

Clone:
1A4

Conjugate:
Unconjugated

Gene:
ACTA2

Gene Alias:
0610041G09Rik; AAT6; ACT-4; acta2; acta2.L; acta2.S; actin; Actin Alpha 2 Smooth Muscle Aorta; actin alpha 2, smooth muscle; Actin Vascular Smooth Muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha 2, smooth muscle, aorta L homeolog; actin, alpha 2, smooth muscle, aorta S homeolog; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha actin 2; Alpha Cardiac Actin; alpha smooth muscle actin; alpha-actin; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-SM-actin; alpha-smooth muscle actin; Aortic Smooth Muscle; ASMA; a-sma; cell growth-inhibiting gene 46 protein; GIG46; Growth Inhibiting Gene 46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, aortic smooth muscle; mymy5; SM actin; sma; SMactin; sm-actin; SMalphaA; smooth muscle; smooth muscle alpha-actin; vascular smooth muscle alpha-actin; wu:fb63d03; XELAEV_18034370mg

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
101121051, 102191486, 11475, 423787, 431847, 59, 733615, 81633

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA1062

--


Antigen:
Cytohesin 1/2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P63034, Q15438, Q99418, Q9QX11

Gene Symbols:
CYTH1, CYTH2

Immunogen:
Purified, His-tagged cytohesin-1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
6G11

Conjugate:
Unconjugated

Gene:
CYTH1

Gene Alias:
ARF exchange factor; ARF nucleotide-binding site opener; ARNO; B2-1; B2-1/ARNO; CLM1; CLM2; CTC-273B12.8; CTH-1; CTS18; CTS18.1; Cyth1; Cyth2; CYTIP; cytoadhesin 1; cytohesin 1; cytohesin 2; cytohesin-1; Cytohesin-2; D17S811E; homolog of secretory protein SEC7; mKIAA4240; mSec7-1; mSec7-2; PH, SEC7 and coiled-coil domain-containing protein 1; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2); pleckstrin homology, Sec7 and coiled-coil domains 1; pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2); Protein ARNO; PSCD1; Pscd2; PSCD2L; SEC7; SEC7 homolog A; SEC7 homolog B; SEC7 homolog B2-1; Sec7b; SEC7L; Sec7p-L; Sec7p-like

Host Species:
Mouse

Purification Method:
PEG precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
19157, 19158, 9266, 9267

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA106200

--


Antigen:
Mitotic Cells

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Total cell lysate of the human bladder carcinoma cell line T24.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Zebrafish

Product Type:
Antibody

Isotype:
IgM

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
8B3G

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA106300

--


Antigen:
E-cadherin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P12830

Gene Symbols:
CDH1

Immunogen:
MCF-7/AZ cells expressing E-cadherin at their cell surface.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Clone:
MB2

Conjugate:
Unconjugated

Gene:
CDH1

Gene Alias:
AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; Um; UVO; Uvomorulin

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
999

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid