MA170045

TCR beta Monoclonal Antibody (H57-597), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA170045-Each-of-1 In Stock ₹ 38,330.88

MA170045 - Each of 1

₹ 38,330.88

In Stock

Quantity

1

Base Price: ₹ 38,330.88

GST (18%): ₹ 6,899.558

Total Price: ₹ 45,230.438

Antigen

TCR beta

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

0

Gene Symbols

Tcrb

Immunogen

Affinity purified D0 -11.10 TCR.

Quantity

250 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone

H57-597

Conjugate

Unconjugated

Gene

Tcrb

Gene Alias

bTCR; FLJ22602; MGC117436; MGC22624; MGC23964; MGC71411; T cell receptor beta chain; t-cell antigen receptor; T-cell receptor; TCR beta; Tcra; Tcrb; TCRbeta; TCRD; Tib; TRA

Host Species

Armenian Hamster

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

21577

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA1-70045 detects alpha/beta TCR in mouse samples
  • MA1-70045 has been successfully used in flow cytometry, immunoprecipitation, immunohistochemistry (frozen sections), and Western blot procedures
  • The MA1-70045 immunogen is affinity purified D0 -11.10 TCR
  • Stable at 4oC
  • For long term storage, aliquot and freeze unused portions at -20oC in volumes appropriate for single usage
  • Avoid repeated freeze/thaw cycles
  • The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response
  • TCR recognition of self-peptides has been linked to autoimmune disease
  • Mutant self-peptides have been associated with tumors
  • Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome
  • Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)
  • The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease (ref5)
  • T Cell and TCR Diversity Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP)
  • A small number of T cells lack both CD4 and CD8 (double negative, DN)
  • Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders
  • Gamma-delta T cells are primarily found within the epithelium
  • They show less TCR diversity and recognize antigens differently than alpha-beta T cells
  • Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.

Compare Similar Items

Show Difference

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Thermo Scientific

MA170045

--


Antigen:
TCR beta

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
0

Gene Symbols:
Tcrb

Immunogen:
Affinity purified D0 -11.10 TCR.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
H57-597

Conjugate:
Unconjugated

Gene:
Tcrb

Gene Alias:
bTCR; FLJ22602; MGC117436; MGC22624; MGC23964; MGC71411; T cell receptor beta chain; t-cell antigen receptor; T-cell receptor; TCR beta; Tcra; Tcrb; TCRbeta; TCRD; Tib; TRA

Host Species:
Armenian Hamster

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21577

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

MA17005

--


Antigen:
Bordetella pertussis LOS-A

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Whole Bordetella pertussis lysate.

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG3

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
D26E

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
B. pertussis; LOS-A

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4°, C

Form:
Liquid

Img

Thermo Scientific

MA170053

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Antigen:
Complement C3b

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P01024, P01027

Gene Symbols:
C3

Immunogen:
Human C3.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry

Clone:
6C9

Conjugate:
Unconjugated

Gene:
C3

Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3a; complement component C3b; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; iC3b; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12266, 718

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA170057

--


Antigen:
Complement Factor H

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P08603

Gene Symbols:
CFH

Immunogen:
Human complement Factor H.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunoprecipitation, Western Blot

Clone:
OX-24

Conjugate:
Unconjugated

Gene:
CFH

Gene Alias:
adrenomedullin binding protein; age-related maculopathy susceptibility 1; AHUS1; AMBP1; ARMD4; ARMS1; beta-1H; beta-1-H-globulin; Cfh; CFHL3; complement component factor H; complement factor H; complement factor H related protein 3A4/5G4; complement factor H, isoform b; complement inhibitory factor H; factor H; factor H-like 1; FH; FHL1; FHL1 antibody; H factor 1; H factor 1 (complement); H factor 2 (complement); HF; HF1; HF2; HGNC:4883; HUS; MGC88246; Mud-1; NOM; platelet complement factor H; protein beta-1-H; RP1-177P10.1; Sas1; Sas-1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3075

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid