MA3-745

Vimentin Monoclonal Antibody (J144), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA3-745-Each-of-1 In Stock ₹ 52,448.28

MA3-745 - Each of 1

₹ 52,448.28

In Stock

Quantity

1

Base Price: ₹ 52,448.28

GST (18%): ₹ 9,440.69

Total Price: ₹ 61,888.97

Antigen

Vimentin

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.05% sodium azide

Gene Accession No.

P08670, P20152, P31000

Gene Symbols

Vim

Immunogen

Human rhabdosarcoma cell line JR1.

Regulatory Status

RUO

Gene ID (Entrez)

22352, 477991, 7431, 81818

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

J144

Conjugate

Unconjugated

Gene

Vim

Gene Alias

cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus

Host Species

Mouse

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgM

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Description

  • MA3-745 detects human, rat, and mouse vimentin and has been successfully used in HELA-S3, HEK-293, rat brain, and rat kidney cells
  • MA3-745 has been successfully used in Western blot, immunohistochemical and immunofluorescence procedures
  • By Western blot, this antibody detects an ∽57 kDa protein representing vimentin from HELA-S3 cells
  • Immunohistochemical staining of vimentin using MA3-745 can be performed
  • The MA3-745 immunogen was human rhabdosarcoma cell line JR1
  • Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin
  • It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane
  • Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development
  • During the development process, vimentin is exchanged for new, tissue-specific IFPs
  • Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets
  • Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event
  • This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.

Compare Similar Items

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Img

Thermo Scientific

MA3-745

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Antigen:
Vimentin

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
P08670, P20152, P31000

Gene Symbols:
Vim

Immunogen:
Human rhabdosarcoma cell line JR1.

Regulatory Status:
RUO

Gene ID (Entrez):
22352, 477991, 7431, 81818

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
J144

Conjugate:
Unconjugated

Gene:
Vim

Gene Alias:
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus

Host Species:
Mouse

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgM

Img

Thermo Scientific

MA3001

--


Antigen:
CDK7

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
P50613, Q03147

Gene Symbols:
CDK7

Immunogen:
Synthetic peptide MALDVKSRAKRYEKLDFLGEGQ corresponding to aa 1-22 of human CDK7

Regulatory Status:
RUO

Gene ID (Entrez):
1022, 12572

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
31TF2-1F8

Conjugate:
Unconjugated

Gene:
CDK7

Gene Alias:
39 KDa protein kinase; 39 protein kinase; AI323415; AI528512; C230069N13; CAK; CAK1; CDK; CDK7; CDK-activating kinase; CDK-activating kinase 1; Cdkn7; cell division protein kinase 7; CR4 protein kinase; CRK4; CRK4 PK (CDC2-related-kinase-4 protein kinase); cyclin dependent kinase 7; cyclin-dependent kinase 7; cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); EC 2.7.11.22; EC 2.7.11.23; HCAK; homolog of Xenopus MO15 Cdk-activating kinase; kinase subunit of CAK; MO15; Mpk-7; OTTHUMP00000222032; OTTHUMP00000222033; p39 Mo15; p39MO15; Protein-tyrosine kinase MPK-7; serine/threonine kinase stk1; serine/threonine protein kinase 1; serine/threonine protein kinase MO15; Serine/threonine-protein kinase 1; STK1; TFIIH basal transcription factor complex kinase subunit

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Thermo Scientific

MA3004

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Antigen:
VCP

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P46462, P55072, Q01853

Gene Symbols:
VCP

Immunogen:
Synthetic peptide corresponding to residues C G(792) G S V Y T E D N D D D L Y G(806) of mouse VCP.

Regulatory Status:
RUO

Gene ID (Entrez):
116643, 269523, 7415

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
5

Conjugate:
Unconjugated

Gene:
VCP

Gene Alias:
15S Mg(2+)-ATPase p97 subunit; 3110001E05; AAA ATPase p97; ALS14; CDC48; cell division cycle gene CDC48; CMT2Y; epididymis luminal protein 220; epididymis secretory protein Li 70; HEL-220; HEL-S-70; homolog of yeast cdc48; IBMPFD; IBMPFD1; Inv protein; or HEL-S-70; p97; p97 atpase; p97/VCP; Protein CDC48; si:ch211-113n10.2; TER ATPase; TERA; transitional endoplasmic reticulum ATPase; valosin containing protein; valosin-containing protein; Vcp; wu:fd16d05; wu:fj63d11; yeast Cdc48p homolog

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

MA3005

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Antigen:
Endothelin 1

Classification:
Monoclonal

Concentration:
2.5 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P05305, P22387, P22388, Q9BG76

Gene Symbols:
EDN1

Immunogen:
Pure endothelin-1 conjugated to KLH.

Regulatory Status:
RUO

Gene ID (Entrez):
13614, 1906, 24323, 443498

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Radioimmune Assays (RIA), Western Blot

Clone:
TR.ET.48.5

Conjugate:
Unconjugated

Gene:
EDN1

Gene Alias:
ARCND3; Big endothelin 1; Big endothelin-1; Big ET; Big ET 1; Big ET1; BigET; EDN1; endothelin 1; endothelin-1; Et; ET1; ET-1; HDLCQ7; PPET1; ppET-1; preproendothelin; preproendothelin-1; preproET; QME

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Ovine, Rat

Product Type:
Antibody

Isotype:
IgG1