MA3027

Calnexin Monoclonal Antibody (AF18), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA3027-Each-of-1 In Stock ₹ 49,582.02

MA3027 - Each of 1

₹ 49,582.02

In Stock

Quantity

1

Base Price: ₹ 49,582.02

GST (18%): ₹ 8,924.764

Total Price: ₹ 58,506.784

Antigen

Calnexin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P27824, P35564

Gene Symbols

CANX

Immunogen

Focus human hepatoma cell lysate.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Immunoprecipitation, Western Blot

Clone

AF18

Conjugate

Unconjugated

Gene

CANX

Gene Alias

1110069N15Rik; AI988026; calmegin; calnexin; canx; canx-a; canx-b; clgn; clnx; cnx; D11Ertd153e; FLJ26570; hypothetical protein; IP90; Major histocompatibility complex class I antigen-binding protein p88; p88; P90; PP90; pp90 precursor

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

12330, 821

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Thermo Scientific

PA130197

--

Img

Thermo Scientific

MA1932

--

Img

Thermo Scientific

PA1066

--

Img

Thermo Scientific

MA1080

--

Img

Thermo Scientific

MA146412

--

Img

Thermo Scientific

MA180331

--

Img

Thermo Scientific

MA124750

--

Img

Thermo Scientific

MA3922

--

Description

  • MA3-027 detects calnexin from human and mouse tissues
  • MA3-027 has been successfully used in Western blot, immunocytochemistry, immunofluorescence and immunoprecipitation protocols
  • By Western blot, this antibody detects calnexin in human liver, skin, adrenal gland, heart, colon, testes and ovary extracts
  • This antibody is not recommended for human kidney or mouse liver lysates in Western blot applications
  • The predicted molecular weight of this antibody is ∽67kDa; however, it may run on SDS-PAGE as an ∽90kDA protein
  • This is due mainly to negative charges at the C-terminus of the protein, which effects the SDS binding to the molecules and consequently its SDS-PAGE mobility
  • Immunocytochemical staining of calnexin in Huh-7 cells with MA3-027 yields a pattern consistent with specific endoplasmic reticulum staining
  • The MA3-027 antigen is Focus human hepatoma cell lysate
  • Calnexin, also referred to as IP90, p88 and p90, is an approximately 90 kDa integral membrane protein of the endoplasmic reticulum (ER)
  • Many resident ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into multisubunit proteins
  • Studies indicate that calnexin associates with the major histocompatibility complex (MHC) class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin, but not with completed receptor complexes
  • It has been shown that calnexin is a chaperone that retains incompletely or improperly folded proteins in the ER
  • The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble ER resident proteins such as GRP78 and GRP94 and protein disulfide isomerase
  • Integral membrane ER resident proteins, like calnexin, often lack this KDEL sequence but contain positively charged cytosolic residues that ensure ER retention
  • Calnexin contains a large ER luminal domain (461 amino acids), a transmembrane segment (22 amino acids), and a cytoplasmic tail (89 amino acids).

Compare Similar Items

Show Difference

Img

Thermo Scientific

MA3027

--


Antigen:
Calnexin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P27824, P35564

Gene Symbols:
CANX

Immunogen:
Focus human hepatoma cell lysate.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Immunoprecipitation, Western Blot

Clone:
AF18

Conjugate:
Unconjugated

Gene:
CANX

Gene Alias:
1110069N15Rik; AI988026; calmegin; calnexin; canx; canx-a; canx-b; clgn; clnx; cnx; D11Ertd153e; FLJ26570; hypothetical protein; IP90; Major histocompatibility complex class I antigen-binding protein p88; p88; P90; PP90; pp90 precursor

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12330, 821

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3028

--


Antigen:
mtHSP70

Classification:
Monoclonal

Concentration:
1.07 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P0DMV8, Q61696

Gene Symbols:
HSPA1A

Immunogen:
Synthetic peptide corresponding to residues G(615) S G S S G T G E Q K E D Q K E E K Q(633) of mouse mtHSP70.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG3

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
JG1

Conjugate:
Unconjugated

Gene:
HSPA1A

Gene Alias:
68 kDa heat shock protein; dnaK-type molecular chaperone HSP70-1; epididymis secretory protein Li 103; heat shock 70 kDa protein 1; heat shock 70 kDa protein 1/2; heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1B; Heat shock 70 kDa protein 2; Heat shock 70 kDa protein 3; heat shock 70kD protein 1A; heat shock 70kDa protein 1A; heat shock protein 1A; heat shock protein family A (Hsp70) member 1A; heat shock protein, 70 kDa 3; heat shock-induced protein; HEL-S-103; Hsp68; HSP70.1; HSP70.1/HSP70.2; Hsp70.3; HSP70-1; HSP70-1/HSP70-2; HSP70-1A; HSP70-2; Hsp70-3; Hsp70A1; HSP70I; Hsp72; HSPA1; Hspa1a; HSPA1B; HSX70; inducible heat shock protein 70

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
193740, 3303

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3030

--


Antigen:
uNOS

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
P29473, P29474, P29475, P29476, P29477, P35228, P70313, Q06518, Q27995, Q62600, Q9Z0J4

Gene Symbols:
NOS1, NOS2, Nos3

Immunogen:
Purified bovine bNOS.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
NOS-3F7-B11 B5

Conjugate:
Unconjugated

Gene:
NOS2

Gene Alias:
2310005C01Rik; 2310065A03Rik; bNOS; cNOS; constitutive NOS; Ecnos; EC-NOS; endothelial nitric oxide synthase; endothelial nitric oxide synthase 3; endothelial NOS; eNOS; Hepatocyte NOS; HEP-NOS; IHPS1; inducible nitric oxid synthase; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; INOS; i-NOS; Inosl; MAC-NOS; macrophage inducible nitric oxide synthase; macrophage NOS; NC-NOS; Neuronal NOS; nitric oxidase synthase; nitric oxide synthase; nitric oxide synthase 1; nitric oxide synthase 1 (neuronal); nitric oxide synthase 1, neuronal; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase 3; nitric oxide synthase 3 (endothelial cell); nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3, endothelial cell; nitric oxide synthase II; nitric oxide synthase, brain; Nitric oxide synthase, endothelial; nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric-oxide synthase; nNOS; N-NOS; NO; NOS; NOS type I; NOS type II; NOS type III; NOS, type II; Nos1; Nos-1; NOS2; Nos-2; Nos2a; Nos3; Nos-3; NOS-I; NOSII; NOS-II; NOSIII; Peptidyl-cysteine S-nitrosylase NOS1; peptidyl-cysteine S-nitrosylase NOS2

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
18125, 18126, 18127, 24598, 24599, 24600, 282876, 287024, 4842, 4843, 4846, 536132

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3031

--


Antigen:
GAL4

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
P04386

Gene Symbols:
GAL4

Immunogen:
Gal4 DNA Binding Domain aa1-147

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Yeast

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Immunocytochemistry, Western Blot

Clone:
2GV-3

Conjugate:
Unconjugated

Gene:
GAL4

Gene Alias:
antigen NY-CO-27; GAL4; Gal-4; GAL81; galactose-responsive transcription factor GAL4; galectin 4; galectin-4; L-36 lactose-binding protein; L36LBP; Lactose-binding lectin 4; lectin, galactoside binding soluble 4; lectin, galactoside-binding, soluble, 4; LGALS4; Regulatory protein GAL4; YPL248C

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
855828

Content And Storage:
-20°C

Form:
Liquid