MA3922

Phospholamban Monoclonal Antibody (2D12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA3922-Each-of-1 In Stock ₹ 48,298.62

MA3922 - Each of 1

₹ 48,298.62

In Stock

Quantity

1

Base Price: ₹ 48,298.62

GST (18%): ₹ 8,693.752

Total Price: ₹ 56,992.372

Antigen

Phospholamban

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P26677, P26678, P61012, P61013, P61014, P61015, P61016

Gene Symbols

PLN

Immunogen

Synthetic peptide corresponding to residues D(2) K V Q Y L T R S A I R R A S T I E M P Q Q A R(25) of canine Phospholamban.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Chicken, Guinea Pig, Human, Mouse, Ovine, Porcine, Rabbit, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

2D12

Conjugate

Unconjugated

Gene

PLN

Gene Alias

cardiac CMH18; Cardiac phospholamban; CMD1P; CMH18; phospholamban; Plb; Plm; PLN; unnamed protein product

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100009299, 100721387, 101102067, 18821, 396378, 397421, 414755, 5350, 64672

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Thermo Scientific

PA1066

--

Img

Thermo Scientific

PA1042

--

Img

Thermo Scientific

PA11043

--

Img

Thermo Scientific

MA1932

--

Img

Thermo Scientific

MA3027

--

Img

Thermo Scientific

PA130197

--

Img

Thermo Scientific

PA1060

--

Img

Thermo Scientific

PA11054

--

Description

  • MA3-922 detects phospholamban (PLB) in rabbit, human, pig, sheep, chicken, canine, guinea porcine, rat, and mouse
  • MA3-922 has been successfully used in Western blot, immunofluorescence, immunohistochemistry and immunoprecipitation procedures
  • By Western blot, this antibody detects a 25 kDa protein under non-reducing conditions representing the pentameric form of PLB and a 5 kDa protein under reducing conditions representing the monomeric form of PLB in canine cardiac extracts
  • Immunofluorescence staining of PLB in rat papillary muscle tissue with MA3-922 results in diffuse staining of the network sarcoplasmic reticulum (SR)
  • MA3-922 can also be used to increase the calcium uptake in ventricular SR vesicles analogous to the phosphorylation of PLB following adrenergic stimulation
  • This antibody is recommended for immunofluorescent staining of tissues
  • The MA3-922 immunogen is a synthetic peptide corresponding to residues D(2) K V Q Y L T R S A I R R A S T I E M P Q Q A R(25) of canine PLB
  • This antibody recognizes an epitope between amino acid residues 9-17 of canine PLB
  • Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR)
  • PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain
  • The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

MA3922

--


Antigen:
Phospholamban

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P26677, P26678, P61012, P61013, P61014, P61015, P61016

Gene Symbols:
PLN

Immunogen:
Synthetic peptide corresponding to residues D(2) K V Q Y L T R S A I R R A S T I E M P Q Q A R(25) of canine Phospholamban.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Chicken, Guinea Pig, Human, Mouse, Ovine, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
2D12

Conjugate:
Unconjugated

Gene:
PLN

Gene Alias:
cardiac CMH18; Cardiac phospholamban; CMD1P; CMH18; phospholamban; Plb; Plm; PLN; unnamed protein product

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100009299, 100721387, 101102067, 18821, 396378, 397421, 414755, 5350, 64672

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3926

--


Antigen:
Sodium/Calcium Exchanger

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P23685, P32418, P48766, P70414, Q01728

Gene Symbols:
SLC8A1

Immunogen:
Purified canine cardiac sodium/calcium exchanger.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Guinea Pig, Human, Mouse, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
C2C12

Conjugate:
Unconjugated

Gene:
SLC8A1

Gene Alias:
AI852629; AV344025; cardiac sarcolemmal sodium-calcium exchanger; CNC; D930008O12Rik; isoform NCX1.13; isoform NCX1.3; isoform NCX1.9; Na(+)/Ca(2+)-exchange protein 1; Na/Ca exchanger; Na/Ca exchanger NACA1 isoform; Na+/C2+ exchanger; Na+/Ca++ exchanger; Na+/Ca2+ exchanger; NACA; Na-Ca exchanger; Ncx; Ncx1; NKX; renal Na/Ca exchanger NACA-2; sarcolemmal sodium/calcium exchanger; SLC8A1; sodium/calcium exchanger; sodium/calcium exchanger 1; sodium/calcium exchanger isoform NaCa13; sodium/calcium exchanger isoform NaCa3; sodium/calcium exchanger isoform NaCa7; sodium/calcium exchanger isoform NaCa9; sodium-calcium exchanger; solute carrier family 8 (sodium/calcium exchanger), member 1; solute carrier family 8 member 1; solute carrier family 8 member A1; solute carrier family 8, member 1

Host Species:
Mouse

Purification Method:
Affinity chromatography - MBP

Regulatory Status:
RUO

Gene ID (Entrez):
100135620, 100328570, 20541, 29715, 475738, 6546

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3927

--


Antigen:
Triadin

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
E9Q9K5, Q28820, Q9QX75

Gene Symbols:
TRDN

Immunogen:
Purified rabbit fast skeletal muscle triadin.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
GE 4.90

Conjugate:
Unconjugated

Gene:
TRDN

Gene Alias:
2310045H21Rik; cardiac triadin; cardiac triadin isoform 1; cardiac triadin isoform 2; cardiac triadin isoform 3; CPVT5; EG432451; junctional sarcoplasmic reticulum glycoprotein; TDN; Trdn; Triadin; triadin 1; triadin 32 kDa (TRISK 32); triadin 49 kDa (TRISK 49); triadin 95; TRISK

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
100009519, 59299, 76757

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3934

--


Antigen:
OATP2

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant with 0.09% sodium azide

Gene Accession No.:
Q9Y6L6

Gene Symbols:
SLCO1B1

Immunogen:
Synthetic peptide corresponding to residues E(671) S L N K N K H F V P S A G A D S E T H C(691) of human OATP2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
ESL

Conjugate:
Unconjugated

Gene:
SLCO1B1

Gene Alias:
HBLRR; liver-specific organic anion transporter 1; LST1; LST-1; OATP1B1; OATP2; OATP-2; OATPC; OATP-C; SLC01B1; SLC21A6; SLCO1B1; Sodium-independent organic anion-transporting polypeptide 2; solute carrier family 21 (organic anion transporter), member 6; Solute carrier family 21 member 6; Solute carrier organic anion transporter family member 1B1; solute carrier organic anion transporter family, member 1B1

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
10599

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid