MA3926

Sodium/Calcium Exchanger Monoclonal Antibody (C2C12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA3926-Each-of-1 In Stock ₹ 44,448.42

MA3926 - Each of 1

₹ 44,448.42

In Stock

Quantity

1

Base Price: ₹ 44,448.42

GST (18%): ₹ 8,000.716

Total Price: ₹ 52,449.136

Antigen

Sodium/Calcium Exchanger

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P23685, P32418, P48766, P70414, Q01728

Gene Symbols

SLC8A1

Immunogen

Purified canine cardiac sodium/calcium exchanger.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Guinea Pig, Human, Mouse, Rabbit, Rat

Product Type

Antibody

Isotype

IgM

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

C2C12

Conjugate

Unconjugated

Gene

SLC8A1

Gene Alias

AI852629; AV344025; cardiac sarcolemmal sodium-calcium exchanger; CNC; D930008O12Rik; isoform NCX1.13; isoform NCX1.3; isoform NCX1.9; Na(+)/Ca(2+)-exchange protein 1; Na/Ca exchanger; Na/Ca exchanger NACA1 isoform; Na+/C2+ exchanger; Na+/Ca++ exchanger; Na+/Ca2+ exchanger; NACA; Na-Ca exchanger; Ncx; Ncx1; NKX; renal Na/Ca exchanger NACA-2; sarcolemmal sodium/calcium exchanger; SLC8A1; sodium/calcium exchanger; sodium/calcium exchanger 1; sodium/calcium exchanger isoform NaCa13; sodium/calcium exchanger isoform NaCa3; sodium/calcium exchanger isoform NaCa7; sodium/calcium exchanger isoform NaCa9; sodium-calcium exchanger; solute carrier family 8 (sodium/calcium exchanger), member 1; solute carrier family 8 member 1; solute carrier family 8 member A1; solute carrier family 8, member 1

Host Species

Mouse

Purification Method

Affinity chromatography - MBP

Regulatory Status

RUO

Gene ID (Entrez)

100135620, 100328570, 20541, 29715, 475738, 6546

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA3-926 detects sodium/calcium exchanger from human, canine, rabbit, mouse, guinea pig and rat kidney and cardiac tissues
  • MA3-926 has been successfully used in Western blot, immunofluorescence, immunohistochemistry, and immunoprecipitation procedures
  • By Western blot, this antibody detects a 120 kDa protein representing the sodium/calcium exchanger from guinea pig cardiac extract
  • The bands seen at 70 kDa and 160 kDa represent a proteolytic fragment and non-reduced exchanger respectively
  • MA3-926 is not recommended for Western blot procedures of rat tissues
  • Immunohistochemical staining of the sodium/calcium exchanger in rat heart with MA3-926 results in staining of the plasma membrane and intense staining of cardiac T-tubular membrane
  • The MA3-926 antigen is purified canine cardiac sodium/calcium exchanger
  • This antibody recognizes an epitope between amino acids 371-525, which is on the intracellular side of the plasma membrane
  • Ca2+ plays a critical role in intracellular signaling and thus regulation of calcium balance is critical for the maintenance of this signaling function
  • The plasma membrane Na+/Ca2+ (NaCX) exchangers mediate Na+-dependent Ca2+ efflux in a wide variety of cell types
  • NaCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane
  • In mammals, at least 5 distinct genes code for the exchangers: Three NaCX (NaCX-1, NaCX-2, and NaCX-3), and two in the NaCKX family (NaCKX-1 and NaCKX-2)
  • NaCX-1 is most prominently expressed in the heart where it plays a major role in excitation-contraction coupling (Matsuoka et al., 1993)
  • NACX-1 may also be a target for protection of the heart and brain from ischemia and reperfusion injury (Hagihara et al., 2005; Bano et al., 2005; Choi, 2005).

Compare Similar Items

Show Difference

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Thermo Scientific

MA3926

--


Antigen:
Sodium/Calcium Exchanger

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P23685, P32418, P48766, P70414, Q01728

Gene Symbols:
SLC8A1

Immunogen:
Purified canine cardiac sodium/calcium exchanger.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Guinea Pig, Human, Mouse, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
C2C12

Conjugate:
Unconjugated

Gene:
SLC8A1

Gene Alias:
AI852629; AV344025; cardiac sarcolemmal sodium-calcium exchanger; CNC; D930008O12Rik; isoform NCX1.13; isoform NCX1.3; isoform NCX1.9; Na(+)/Ca(2+)-exchange protein 1; Na/Ca exchanger; Na/Ca exchanger NACA1 isoform; Na+/C2+ exchanger; Na+/Ca++ exchanger; Na+/Ca2+ exchanger; NACA; Na-Ca exchanger; Ncx; Ncx1; NKX; renal Na/Ca exchanger NACA-2; sarcolemmal sodium/calcium exchanger; SLC8A1; sodium/calcium exchanger; sodium/calcium exchanger 1; sodium/calcium exchanger isoform NaCa13; sodium/calcium exchanger isoform NaCa3; sodium/calcium exchanger isoform NaCa7; sodium/calcium exchanger isoform NaCa9; sodium-calcium exchanger; solute carrier family 8 (sodium/calcium exchanger), member 1; solute carrier family 8 member 1; solute carrier family 8 member A1; solute carrier family 8, member 1

Host Species:
Mouse

Purification Method:
Affinity chromatography - MBP

Regulatory Status:
RUO

Gene ID (Entrez):
100135620, 100328570, 20541, 29715, 475738, 6546

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3927

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Antigen:
Triadin

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
E9Q9K5, Q28820, Q9QX75

Gene Symbols:
TRDN

Immunogen:
Purified rabbit fast skeletal muscle triadin.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
GE 4.90

Conjugate:
Unconjugated

Gene:
TRDN

Gene Alias:
2310045H21Rik; cardiac triadin; cardiac triadin isoform 1; cardiac triadin isoform 2; cardiac triadin isoform 3; CPVT5; EG432451; junctional sarcoplasmic reticulum glycoprotein; TDN; Trdn; Triadin; triadin 1; triadin 32 kDa (TRISK 32); triadin 49 kDa (TRISK 49); triadin 95; TRISK

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
100009519, 59299, 76757

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3934

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Antigen:
OATP2

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant with 0.09% sodium azide

Gene Accession No.:
Q9Y6L6

Gene Symbols:
SLCO1B1

Immunogen:
Synthetic peptide corresponding to residues E(671) S L N K N K H F V P S A G A D S E T H C(691) of human OATP2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
ESL

Conjugate:
Unconjugated

Gene:
SLCO1B1

Gene Alias:
HBLRR; liver-specific organic anion transporter 1; LST1; LST-1; OATP1B1; OATP2; OATP-2; OATPC; OATP-C; SLC01B1; SLC21A6; SLCO1B1; Sodium-independent organic anion-transporting polypeptide 2; solute carrier family 21 (organic anion transporter), member 6; Solute carrier family 21 member 6; Solute carrier organic anion transporter family member 1B1; solute carrier organic anion transporter family, member 1B1

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
10599

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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Thermo Scientific

MA3940

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Antigen:
Mu-Calpain

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
O35350, P06815, P07384, P35750, P97571, Q27970

Gene Symbols:
CAPN1

Immunogen:
Purified bovine skeletal muscle 80 kDa mu-calpain subunit.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Hamster, Human, Mouse, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
9A4H8D3

Conjugate:
Unconjugated

Gene:
CAPN1

Gene Alias:
calcium activated neutral protease; calcium-activated neutral protease 1; calcium-activated neutral proteinase 1; calcium-dependent protease; calpain; calpain 1; calpain 1 large subunit; calpain 1, (mu/I) large subunit; calpain 1, large subunit; calpain mu-type; calpain, large polypeptide L1; calpain-1 catalytic subunit; Calpain-1 large subunit; Calpain-I; Calpain-II; CANP; CANP 1; Canp1; CANPL1; Capa1; Capa-1; Capn1; Cell proliferation-inducing gene 30 protein; cell proliferation-inducing protein 30; Cls1; I79_024883; micromolar calcium-activated neutral protease 1; micromolar calcium-activated neutral protease 1 isoform A; micromolar calcium-activated neutral protease 1 isoform B; micromolar calcium-dependent neutral protease large subunit; micromolar-calpain; mucalpain; mu-calpain; mu-calpin; muCANP; muCL; PIG30; SPG76

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100009089, 100758636, 12333, 281661, 29153, 397027, 823

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid