MA3920

CaV1.1 Monoclonal Antibody (1A), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA3920-Each-of-1 In Stock ₹ 44,448.42

MA3920 - Each of 1

₹ 44,448.42

In Stock

Quantity

1

Base Price: ₹ 44,448.42

GST (18%): ₹ 8,000.716

Total Price: ₹ 52,449.136

Antigen

CaV1.1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide; pH 7.4

Gene Accession No.

P07293, Q02485, Q02789, Q13698

Gene Symbols

CACNA1S

Immunogen

Purified rabbit muscle T-tubule dihydropyridine receptor.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Guinea Pig, Human, Mouse, Rabbit, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

1A

Conjugate

Unconjugated

Gene

CACNA1S

Gene Alias

AW493108; CACH1; Cacn1; Cacna1s; Cacnl1a3; calcium channel, L type, alpha 1 polypeptide, isoform 3 (skeletal muscle, hypokalemic periodic paralysis); calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle; calcium channel, voltage-dependent, L type, alpha 1S subunit; calcium voltage-gated channel subunit alpha1 S; Cav1.1; Cav1.1 alpha-1; CCHL1A3; DHP; DHPR; DHPR alpha1s; dihydropyridine calcium channel receptor protein; dihydropyridine receptor; dihydropyridine receptor alpha 1 subunit; dihydropyridine receptor alpha 1S; dihydropyridine receptor alpha-1S subunit; dihydropyridine-sensitive L-type calcium channel alpha-1 subunit; fmd; HOKPP; HOKPP1; hypoPP; mdg; MHS5; muscle dysgenesis; ROB1; sj; TTPP1; unnamed protein product; voltage-dependent L-type calcium channel subunit alpha-1S; Voltage-gated calcium channel subunit alpha Cav1.1

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100009585, 100734741, 12292, 682930, 779

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA3-920 detects 1,4-dihydropyridine (DHP) receptor alpha-1 subunit in human, rat, mouse, guinea pig and rabbit skeletal muscle
  • The DHP Receptor alpha-1 protein is also known as CACNA1S or Cav1.1 alpha-1 subunit
  • MA3-920 has been successfully used in Western blot, FACS, immunohistochemistry and immunoprecipitation procedures
  • By Western blot, this antibody detects an ∽200 kDa protein representing the DHP receptor in rat skeletal muscle extracts
  • Immunohistochemical staining of DHP receptor in rabbit skeletal muscle with MA3-920 results in double rows of discrete punctate staining representing pairs of triads on the opposing sides of the Z-lines
  • This product can be used to inhibit the DHP-sensitive calcium current in BC3H1 mouse muscle cells
  • The MA3-920 antigen is purified rabbit muscle T-tubule DHP receptor
  • Voltage-sensitive calcium channels mediate the entry of calcium into many types of excitable cells and thus play a key role in neurotransmitter release and excitation-contraction (E-C) coupling
  • The 1,4-dihydropyridines (DHPs) are synthetic organic compounds which can be used to identify the L-type calcium channels that are found in all types of vertebrate muscle, neuronal and neuroendocrine cells
  • The DHP receptor is part of the L-type calcium channel complex and is thought to be the voltage sensor in E-C coupling
  • The purified DHP receptor isolated from triads is composed of at least four subunits
  • The alpha-1 subunit contains the binding site for the DHPs and shows high sequence homology to the voltage gated sodium channel
  • The alpha-2 subunit is a large glycoprotein associated with the DHP receptor which was first described in skeletal muscle and is also found in high concentrations in other excitable tissues such as cardiac muscle and brain and in low concentrations in most other tissues studied
  • The other two subunits that co-purify with the DHP receptor are termed beta and gamma.

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Thermo Scientific

MA3920

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Antigen:
CaV1.1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide; pH 7.4

Gene Accession No.:
P07293, Q02485, Q02789, Q13698

Gene Symbols:
CACNA1S

Immunogen:
Purified rabbit muscle T-tubule dihydropyridine receptor.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Guinea Pig, Human, Mouse, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
1A

Conjugate:
Unconjugated

Gene:
CACNA1S

Gene Alias:
AW493108; CACH1; Cacn1; Cacna1s; Cacnl1a3; calcium channel, L type, alpha 1 polypeptide, isoform 3 (skeletal muscle, hypokalemic periodic paralysis); calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle; calcium channel, voltage-dependent, L type, alpha 1S subunit; calcium voltage-gated channel subunit alpha1 S; Cav1.1; Cav1.1 alpha-1; CCHL1A3; DHP; DHPR; DHPR alpha1s; dihydropyridine calcium channel receptor protein; dihydropyridine receptor; dihydropyridine receptor alpha 1 subunit; dihydropyridine receptor alpha 1S; dihydropyridine receptor alpha-1S subunit; dihydropyridine-sensitive L-type calcium channel alpha-1 subunit; fmd; HOKPP; HOKPP1; hypoPP; mdg; MHS5; muscle dysgenesis; ROB1; sj; TTPP1; unnamed protein product; voltage-dependent L-type calcium channel subunit alpha-1S; Voltage-gated calcium channel subunit alpha Cav1.1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100009585, 100734741, 12292, 682930, 779

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3922

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Antigen:
Phospholamban

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P26677, P26678, P61012, P61013, P61014, P61015, P61016

Gene Symbols:
PLN

Immunogen:
Synthetic peptide corresponding to residues D(2) K V Q Y L T R S A I R R A S T I E M P Q Q A R(25) of canine Phospholamban.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Chicken, Guinea Pig, Human, Mouse, Ovine, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
2D12

Conjugate:
Unconjugated

Gene:
PLN

Gene Alias:
cardiac CMH18; Cardiac phospholamban; CMD1P; CMH18; phospholamban; Plb; Plm; PLN; unnamed protein product

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100009299, 100721387, 101102067, 18821, 396378, 397421, 414755, 5350, 64672

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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MA3926

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Antigen:
Sodium/Calcium Exchanger

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P23685, P32418, P48766, P70414, Q01728

Gene Symbols:
SLC8A1

Immunogen:
Purified canine cardiac sodium/calcium exchanger.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Guinea Pig, Human, Mouse, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
C2C12

Conjugate:
Unconjugated

Gene:
SLC8A1

Gene Alias:
AI852629; AV344025; cardiac sarcolemmal sodium-calcium exchanger; CNC; D930008O12Rik; isoform NCX1.13; isoform NCX1.3; isoform NCX1.9; Na(+)/Ca(2+)-exchange protein 1; Na/Ca exchanger; Na/Ca exchanger NACA1 isoform; Na+/C2+ exchanger; Na+/Ca++ exchanger; Na+/Ca2+ exchanger; NACA; Na-Ca exchanger; Ncx; Ncx1; NKX; renal Na/Ca exchanger NACA-2; sarcolemmal sodium/calcium exchanger; SLC8A1; sodium/calcium exchanger; sodium/calcium exchanger 1; sodium/calcium exchanger isoform NaCa13; sodium/calcium exchanger isoform NaCa3; sodium/calcium exchanger isoform NaCa7; sodium/calcium exchanger isoform NaCa9; sodium-calcium exchanger; solute carrier family 8 (sodium/calcium exchanger), member 1; solute carrier family 8 member 1; solute carrier family 8 member A1; solute carrier family 8, member 1

Host Species:
Mouse

Purification Method:
Affinity chromatography - MBP

Regulatory Status:
RUO

Gene ID (Entrez):
100135620, 100328570, 20541, 29715, 475738, 6546

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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Thermo Scientific

MA3927

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Antigen:
Triadin

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
E9Q9K5, Q28820, Q9QX75

Gene Symbols:
TRDN

Immunogen:
Purified rabbit fast skeletal muscle triadin.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
GE 4.90

Conjugate:
Unconjugated

Gene:
TRDN

Gene Alias:
2310045H21Rik; cardiac triadin; cardiac triadin isoform 1; cardiac triadin isoform 2; cardiac triadin isoform 3; CPVT5; EG432451; junctional sarcoplasmic reticulum glycoprotein; TDN; Trdn; Triadin; triadin 1; triadin 32 kDa (TRISK 32); triadin 49 kDa (TRISK 49); triadin 95; TRISK

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
100009519, 59299, 76757

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid