MA3028

mtHSP70 Monoclonal Antibody (JG1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA3028-Each-of-1 In Stock ₹ 45,817.38

MA3028 - Each of 1

₹ 45,817.38

In Stock

Quantity

1

Base Price: ₹ 45,817.38

GST (18%): ₹ 8,247.128

Total Price: ₹ 54,064.508

Antigen

mtHSP70

Classification

Monoclonal

Concentration

1.07 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P0DMV8, Q61696

Gene Symbols

HSPA1A

Immunogen

Synthetic peptide corresponding to residues G(615) S G S S G T G E Q K E D Q K E E K Q(633) of mouse mtHSP70.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG3

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

JG1

Conjugate

Unconjugated

Gene

HSPA1A

Gene Alias

68 kDa heat shock protein; dnaK-type molecular chaperone HSP70-1; epididymis secretory protein Li 103; heat shock 70 kDa protein 1; heat shock 70 kDa protein 1/2; heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1B; Heat shock 70 kDa protein 2; Heat shock 70 kDa protein 3; heat shock 70kD protein 1A; heat shock 70kDa protein 1A; heat shock protein 1A; heat shock protein family A (Hsp70) member 1A; heat shock protein, 70 kDa 3; heat shock-induced protein; HEL-S-103; Hsp68; HSP70.1; HSP70.1/HSP70.2; Hsp70.3; HSP70-1; HSP70-1/HSP70-2; HSP70-1A; HSP70-2; Hsp70-3; Hsp70A1; HSP70I; Hsp72; HSPA1; Hspa1a; HSPA1B; HSX70; inducible heat shock protein 70

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

193740, 3303

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA3-028 detects mitochondrial heat shock protein 70 kDa (mtHSP70) from human, non-human primate, canine and mouse tissues
  • MA3-028 has been successfully used in Western blot, immunocytochemical, immunofluorescence, immunohistochemical (paraffin), and immunoprecipitation procedures
  • By Western blot, this antibody detects a single ∽75 kDa band representing mtHSP70 from U2OS cell homogenate
  • Immunocytochemical staining of mtHSP70 in DAP.3 cells with MA3-028 results in a worm-like staining pattern, consistent with mitochondrial localization
  • Antibodies to this protein (and modification) were previously sold as part of a Thermo Scientific Cellomics High Content Screening Kit
  • This replacement antibody is now recommended for researchers who need an antibody for high content cell based assays
  • It has been thoroughly tested and validated for cellular immunofluorescence (IF) applications
  • Further optimization including the selection of the most appropriate fluorescent Dylight conjugated secondary antibody may have to be performed for your high content assay
  • The HSP70 family is a set of highly conserved proteins that are induced by a variety of biological stresses, including heat stress, in every organism in which the proteins have been examined
  • The human HSP70 family members include: HSP70, a 70 kDa protein which is strongly inducible in all organisms but which is also constitutively expressed in primate cells; HSP72, a 72 kDa protein which is induced exclusively under stress conditions; HSC70, or cognate protein, is a 72 kDa constitutively expressed protein which is involved in uncoating clathrin-coated vesicles; GRP78, or BiP, is a glucose-regulated 78 kDa protein localized to the endoplasmic reticulum; and mitochondrial HSP70 (mtHSP70, GRP75 or mortalin) a 75 kDa protein that is found within the mitochondria
  • mtHSP70 is a mitochondrial resident protein that is involved in protein translocation into the mitochondria
  • Preproteins cross the mitochondrial membranes in an extended conformation
  • This requires unfolding of preproteins before entering translocation pores in the mitochondrial outer membrane
  • Preprotein unfolding is thought to be mediated by mtHSP70 and other inner membrane proteins of the mitochondria.

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Show Difference

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Thermo Scientific

MA3028

--


Antigen:
mtHSP70

Classification:
Monoclonal

Concentration:
1.07 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P0DMV8, Q61696

Gene Symbols:
HSPA1A

Immunogen:
Synthetic peptide corresponding to residues G(615) S G S S G T G E Q K E D Q K E E K Q(633) of mouse mtHSP70.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG3

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
JG1

Conjugate:
Unconjugated

Gene:
HSPA1A

Gene Alias:
68 kDa heat shock protein; dnaK-type molecular chaperone HSP70-1; epididymis secretory protein Li 103; heat shock 70 kDa protein 1; heat shock 70 kDa protein 1/2; heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1B; Heat shock 70 kDa protein 2; Heat shock 70 kDa protein 3; heat shock 70kD protein 1A; heat shock 70kDa protein 1A; heat shock protein 1A; heat shock protein family A (Hsp70) member 1A; heat shock protein, 70 kDa 3; heat shock-induced protein; HEL-S-103; Hsp68; HSP70.1; HSP70.1/HSP70.2; Hsp70.3; HSP70-1; HSP70-1/HSP70-2; HSP70-1A; HSP70-2; Hsp70-3; Hsp70A1; HSP70I; Hsp72; HSPA1; Hspa1a; HSPA1B; HSX70; inducible heat shock protein 70

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
193740, 3303

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3030

--


Antigen:
uNOS

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
P29473, P29474, P29475, P29476, P29477, P35228, P70313, Q06518, Q27995, Q62600, Q9Z0J4

Gene Symbols:
NOS1, NOS2, Nos3

Immunogen:
Purified bovine bNOS.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
NOS-3F7-B11 B5

Conjugate:
Unconjugated

Gene:
NOS2

Gene Alias:
2310005C01Rik; 2310065A03Rik; bNOS; cNOS; constitutive NOS; Ecnos; EC-NOS; endothelial nitric oxide synthase; endothelial nitric oxide synthase 3; endothelial NOS; eNOS; Hepatocyte NOS; HEP-NOS; IHPS1; inducible nitric oxid synthase; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; INOS; i-NOS; Inosl; MAC-NOS; macrophage inducible nitric oxide synthase; macrophage NOS; NC-NOS; Neuronal NOS; nitric oxidase synthase; nitric oxide synthase; nitric oxide synthase 1; nitric oxide synthase 1 (neuronal); nitric oxide synthase 1, neuronal; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase 3; nitric oxide synthase 3 (endothelial cell); nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3, endothelial cell; nitric oxide synthase II; nitric oxide synthase, brain; Nitric oxide synthase, endothelial; nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric-oxide synthase; nNOS; N-NOS; NO; NOS; NOS type I; NOS type II; NOS type III; NOS, type II; Nos1; Nos-1; NOS2; Nos-2; Nos2a; Nos3; Nos-3; NOS-I; NOSII; NOS-II; NOSIII; Peptidyl-cysteine S-nitrosylase NOS1; peptidyl-cysteine S-nitrosylase NOS2

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
18125, 18126, 18127, 24598, 24599, 24600, 282876, 287024, 4842, 4843, 4846, 536132

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3031

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Antigen:
GAL4

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
P04386

Gene Symbols:
GAL4

Immunogen:
Gal4 DNA Binding Domain aa1-147

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Yeast

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Immunocytochemistry, Western Blot

Clone:
2GV-3

Conjugate:
Unconjugated

Gene:
GAL4

Gene Alias:
antigen NY-CO-27; GAL4; Gal-4; GAL81; galactose-responsive transcription factor GAL4; galectin 4; galectin-4; L-36 lactose-binding protein; L36LBP; Lactose-binding lectin 4; lectin, galactoside binding soluble 4; lectin, galactoside-binding, soluble, 4; LGALS4; Regulatory protein GAL4; YPL248C

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
855828

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

MA3038

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Antigen:
GSK3 alpha/beta

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
P18265, P18266, P49840, P49841, P83101, Q2NL51, Q9WV60

Gene Symbols:
GSK3A, GSK3B, gskt, Pk34A

Immunogen:
Synthetic peptide corresponding to residues 203-219 of drosophila GSK-3 coupled to ovalbumin: KQLLHGEPNVSYICSRY

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Canine, Drosophila, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Immunoprecipitation, Western Blot

Clone:
4G-1E

Conjugate:
Unconjugated

Gene:
GSK3B

Gene Alias:
2700086H06Rik; 7330414F15Rik; 8430431H08Rik; C86142; FA; factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 alpha; Glycogen synthase kinase-3 beta; GSK3; GSK-3; GSK-3 alpha; GSK-3 beta; Gsk3a; gsk-3-alpha; Gsk3b; GSK-3beta; GSK3beta isoform; serine/threonine-protein kinase GSK3A; Serine/threonine-protein kinase GSK3B

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
2931, 2932, 318552, 34705, 478575, 484476, 50686, 56637, 606496, 84027

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid