MA3038
GSK3 alpha/beta Monoclonal Antibody (4G-1E), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3038-Each-of-1 | In Stock | ₹ 48,041.94 |
MA3038 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,041.94
GST (18%): ₹ 8,647.549
Total Price: ₹ 56,689.489
Antigen
GSK3 alpha/beta
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.05% sodium azide
Gene Accession No.
P18265, P18266, P49840, P49841, P83101, Q2NL51, Q9WV60
Gene Symbols
GSK3A, GSK3B, gskt, Pk34A
Immunogen
Synthetic peptide corresponding to residues 203-219 of drosophila GSK-3 coupled to ovalbumin: KQLLHGEPNVSYICSRY
Regulatory Status
RUO
Gene ID (Entrez)
2931, 2932, 318552, 34705, 478575, 484476, 50686, 56637, 606496, 84027
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Immunoprecipitation, Western Blot
Clone
4G-1E
Conjugate
Unconjugated
Gene
GSK3B
Gene Alias
2700086H06Rik; 7330414F15Rik; 8430431H08Rik; C86142; FA; factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 alpha; Glycogen synthase kinase-3 beta; GSK3; GSK-3; GSK-3 alpha; GSK-3 beta; Gsk3a; gsk-3-alpha; Gsk3b; GSK-3beta; GSK3beta isoform; serine/threonine-protein kinase GSK3A; Serine/threonine-protein kinase GSK3B
Host Species
Mouse
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Canine, Drosophila, Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA3-038 detects GSK3 alpha/beta in Human, Mouse, Rat Canine, and Non-human primate samples
- Immunogen is a synthetic peptide corresponding to residues 203-219 of drosophila GSK-3, which is highly conserved across multiple species
- Glycogen synthase kinase-3 (GSK3) is a protein kinase that was originally identified as a regulator of glycogen synthase, a key enzyme in glycogen metabolism
- Since then, it has been shown to be involved in the regulation of a diverse array of cellular functions, including protein synthesis, cell proliferation, cell differentiation, microtubule assembly/disassembly, and apoptosis
- GSK3's substrate specificity is unique in that phosphorylation of the substrate only occurs if a phosphoserine or phosphotyrosine is present - four residues C-terminal to the site of GSK phosphorylation
- There exists two isoforms of GSK3, GSK3 alpha and GSK3 beta, and they are strictly regulated via phosphorylation
- Phosphorylation of GSK3 beta on Ser9 (Ser21 in GSK3alpha) by protein kinase B (PKB) causes its inactivation and is the primary mechanism responsible for growth factor inhibition of this kinase
- Activation of GSK3 beta is dependent upon the phosphorylation of Tyr216 (Tyr279 in GSK3 alpha)
- Upon activation, it has been shown to phosphorylate a number of different cellular proteins, including p53, c-Myc, c-Jun, heat shock factor-1 (HSF-1), and cyclin D1
- GSK3 beta also has been shown to phosphorylate aberrant sites on the microtubule associated protein tau, which is critical for the progression of Alzheimer's disease.
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Antigen: GSK3 alpha/beta
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.05% sodium azide
Gene Accession No.: P18265, P18266, P49840, P49841, P83101, Q2NL51, Q9WV60
Gene Symbols: GSK3A, GSK3B, gskt, Pk34A
Immunogen: Synthetic peptide corresponding to residues 203-219 of drosophila GSK-3 coupled to ovalbumin: KQLLHGEPNVSYICSRY
Regulatory Status: RUO
Gene ID (Entrez): 2931, 2932, 318552, 34705, 478575, 484476, 50686, 56637, 606496, 84027
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Immunoprecipitation, Western Blot
Clone: 4G-1E
Conjugate: Unconjugated
Gene: GSK3B
Gene Alias: 2700086H06Rik; 7330414F15Rik; 8430431H08Rik; C86142; FA; factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 alpha; Glycogen synthase kinase-3 beta; GSK3; GSK-3; GSK-3 alpha; GSK-3 beta; Gsk3a; gsk-3-alpha; Gsk3b; GSK-3beta; GSK3beta isoform; serine/threonine-protein kinase GSK3A; Serine/threonine-protein kinase GSK3B
Host Species: Mouse
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Canine, Drosophila, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG1
Antigen:
GSK3 alpha/beta
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.05% sodium azide
Gene Accession No.:
P18265, P18266, P49840, P49841, P83101, Q2NL51, Q9WV60
Gene Symbols:
GSK3A, GSK3B, gskt, Pk34A
Immunogen:
Synthetic peptide corresponding to residues 203-219 of drosophila GSK-3 coupled to ovalbumin: KQLLHGEPNVSYICSRY
Regulatory Status:
RUO
Gene ID (Entrez):
2931, 2932, 318552, 34705, 478575, 484476, 50686, 56637, 606496, 84027
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Immunoprecipitation, Western Blot
Clone:
4G-1E
Conjugate:
Unconjugated
Gene:
GSK3B
Gene Alias:
2700086H06Rik; 7330414F15Rik; 8430431H08Rik; C86142; FA; factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 alpha; Glycogen synthase kinase-3 beta; GSK3; GSK-3; GSK-3 alpha; GSK-3 beta; Gsk3a; gsk-3-alpha; Gsk3b; GSK-3beta; GSK3beta isoform; serine/threonine-protein kinase GSK3A; Serine/threonine-protein kinase GSK3B
Host Species:
Mouse
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Canine, Drosophila, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG1
Antigen: Huntingtin
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.05% sodium azide
Gene Accession No.: P42858, P42859, P51111
Gene Symbols: Htt
Immunogen: Huntingtin fragment from aa 181 to 810
Regulatory Status: RUO
Gene ID (Entrez): 15194, 29424, 3064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: 1HU-4C8
Conjugate: Unconjugated
Gene: Htt
Gene Alias: AI256365; C430023I11Rik; Hd; HD protein; HD protein homolog; Hdh; HTT; Huntingtin; huntingtin (Huntington disease); Huntingtin, myristoylated N-terminal fragment; Huntington disease gene homolog; huntington disease protein; huntington disease protein homolog; IT15; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Host Species: Mouse
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Huntingtin
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.05% sodium azide
Gene Accession No.:
P42858, P42859, P51111
Gene Symbols:
Htt
Immunogen:
Huntingtin fragment from aa 181 to 810
Regulatory Status:
RUO
Gene ID (Entrez):
15194, 29424, 3064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
1HU-4C8
Conjugate:
Unconjugated
Gene:
Htt
Gene Alias:
AI256365; C430023I11Rik; Hd; HD protein; HD protein homolog; Hdh; HTT; Huntingtin; huntingtin (Huntington disease); Huntingtin, myristoylated N-terminal fragment; Huntington disease gene homolog; huntington disease protein; huntington disease protein homolog; IT15; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Host Species:
Mouse
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CHRM2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: antibody with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P06199, P08172, P10980, Q9ERZ4
Gene Symbols: CHRM2
Immunogen: Purified porcine cardiac m2 muscarinic acetylcholine receptor.
Regulatory Status: RUO
Gene ID (Entrez): 1129, 243764, 397498, 81645
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 31-1D1
Conjugate: Unconjugated
Gene: CHRM2
Gene Alias: 7TM receptor; acetylcholine receptor; acetylcholine receptor, muscarinic 2; AChR M2; AChR-M2; Acm2; cardiac muscarinic acetylcholine receptor; cholinergic receptor; cholinergic receptor muscarinic 2; cholinergic receptor, muscarinic 2; cholinergic receptor, muscarinic 2, cardiac; cholinergic receptor, muscarinic 2, isoform a; Chrm2; Chrm-2; FLJ43243; HM2; M2; M2 muscarinic acetylcholine receptor; m2AChR; M2-mAChR; MGC120006; MGC120007; muscarinic acetylcholine receptor 2; muscarinic acetylcholine receptor m2; muscarinic M2 receptor; muscarinic receptor m2; unnamed protein product
Host Species: Mouse
Quantity: 250 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine, Rat
Product Type: Antibody
Isotype: IgG1
Antigen:
CHRM2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
antibody with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P06199, P08172, P10980, Q9ERZ4
Gene Symbols:
CHRM2
Immunogen:
Purified porcine cardiac m2 muscarinic acetylcholine receptor.
Regulatory Status:
RUO
Gene ID (Entrez):
1129, 243764, 397498, 81645
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
31-1D1
Conjugate:
Unconjugated
Gene:
CHRM2
Gene Alias:
7TM receptor; acetylcholine receptor; acetylcholine receptor, muscarinic 2; AChR M2; AChR-M2; Acm2; cardiac muscarinic acetylcholine receptor; cholinergic receptor; cholinergic receptor muscarinic 2; cholinergic receptor, muscarinic 2; cholinergic receptor, muscarinic 2, cardiac; cholinergic receptor, muscarinic 2, isoform a; Chrm2; Chrm-2; FLJ43243; HM2; M2; M2 muscarinic acetylcholine receptor; m2AChR; M2-mAChR; MGC120006; MGC120007; muscarinic acetylcholine receptor 2; muscarinic acetylcholine receptor m2; muscarinic M2 receptor; muscarinic receptor m2; unnamed protein product
Host Species:
Mouse
Quantity:
250 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG1
Antigen: GCN5
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.05% sodium azide
Gene Accession No.: Q92830
Gene Symbols: KAT2A
Immunogen: Synthetic peptide coupled to ovalbumin corresponding to amino acids 118-132 of human GCN5: CKCNGWKNPKPPTAP.
Regulatory Status: RUO
Gene ID (Entrez): 2648
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ChIP Assay, Western Blot
Clone: 2GC-2C11
Conjugate: Unconjugated
Gene: KAT2A
Gene Alias: 1110051E14Rik; AAS104; ADA4; AW212720; GCN5; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5 general control of amino acid synthesis-like 2; Gcn5l2; general control of amino acid synthesis 5-like 2; general control of amino acid synthesis protein 5-like 2; general control of amino acid synthesis, yeast homolog-like 2; General control of amino acid synthesis, yeast, homolog-like 2; general control of amino acid synthesis-like 2; hGCN5; Histone acetyltransferase GCN5; histone acetyltransferase KAT2A; Histone succinyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; KAT2; Kat2a; KATA2; Lysine acetyltransferase 2A; MmGCN5; PCAF-b; PCAF-B/GCN5; STAF97; SWI9; YGR252W
Host Species: Mouse
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
GCN5
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.05% sodium azide
Gene Accession No.:
Q92830
Gene Symbols:
KAT2A
Immunogen:
Synthetic peptide coupled to ovalbumin corresponding to amino acids 118-132 of human GCN5: CKCNGWKNPKPPTAP.
Regulatory Status:
RUO
Gene ID (Entrez):
2648
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ChIP Assay, Western Blot
Clone:
2GC-2C11
Conjugate:
Unconjugated
Gene:
KAT2A
Gene Alias:
1110051E14Rik; AAS104; ADA4; AW212720; GCN5; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5 general control of amino acid synthesis-like 2; Gcn5l2; general control of amino acid synthesis 5-like 2; general control of amino acid synthesis protein 5-like 2; general control of amino acid synthesis, yeast homolog-like 2; General control of amino acid synthesis, yeast, homolog-like 2; general control of amino acid synthesis-like 2; hGCN5; Histone acetyltransferase GCN5; histone acetyltransferase KAT2A; Histone succinyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; KAT2; Kat2a; KATA2; Lysine acetyltransferase 2A; MmGCN5; PCAF-b; PCAF-B/GCN5; STAF97; SWI9; YGR252W
Host Species:
Mouse
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1