MA1720
GRK1 Monoclonal Antibody (G8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA1720-Each-of-1 | In Stock | ₹ 44,448.42 |
MA1720 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,448.42
GST (18%): ₹ 8,000.716
Total Price: ₹ 52,449.136
Antigen
GRK1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
antibody with 0.05% sodium azide
Gene Accession No.
P28327, Q15835, Q63651, Q9WVL4
Gene Symbols
GRK1
Immunogen
Full length human GRK1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Bovine, Chicken, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone
G8
Conjugate
Unconjugated
Gene
GRK1
Gene Alias
G protein-coupled receptor kinase 1; G protein-coupled receptpr kinase 1; GPRK1; G-protein coupled receptor kinase 1; G-protein receptor kinase 1; GRK 1a/b; GRK1; GRK1a; rhodopsin kinase; rhodopsin kinase GRK1; Rhok; RK
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
24013, 281457, 395431, 6011, 81760
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-720 detects G-protein-associated rhodopsin kinase 1a (GRK1a) from human, mouse, rat, bovine and chicken tissues
- MA1-720 has been successfully used in Western blot, immunofluorescence and immunoprecipitation procedures
- By Western blot, this antibody detects an ∽60 kDa protein representing GRK1a from bovine rod outer segments
- Immunofluorescence staining of GRK1a in bovine retina with MA1-720 results in intense staining primarily in cone outer segments, but also in rod outer segments
- Weak staining is observed in somata and synaptic terminals of cones and inner segments of rods
- The MA1-720 immunogen is full length human GRK1
- This antibody recognizes an epitope in the C-terminal region of GRK1a
- GRK1 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinases
- GRK1 mediates rapid desensitization of rod photoreceptors to light by catalyzing phosphorylation of the visual pigment rhodopsin which leads to its deactivation
- Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2)
- GRK1 can be phosphorylated by PKA and this reduces the ability of GRK1 to phosphorylate rhodopsin in vitro
- It is speculated that phosphorylation of GRK1 by PKA in vivo occurs in the dark when cAMP levels in photoreceptor cells are elevated.
Compare Similar Items
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Antigen: GRK1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: antibody with 0.05% sodium azide
Gene Accession No.: P28327, Q15835, Q63651, Q9WVL4
Gene Symbols: GRK1
Immunogen: Full length human GRK1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Chicken, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: G8
Conjugate: Unconjugated
Gene: GRK1
Gene Alias: G protein-coupled receptor kinase 1; G protein-coupled receptpr kinase 1; GPRK1; G-protein coupled receptor kinase 1; G-protein receptor kinase 1; GRK 1a/b; GRK1; GRK1a; rhodopsin kinase; rhodopsin kinase GRK1; Rhok; RK
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 24013, 281457, 395431, 6011, 81760
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
GRK1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
antibody with 0.05% sodium azide
Gene Accession No.:
P28327, Q15835, Q63651, Q9WVL4
Gene Symbols:
GRK1
Immunogen:
Full length human GRK1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Chicken, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
G8
Conjugate:
Unconjugated
Gene:
GRK1
Gene Alias:
G protein-coupled receptor kinase 1; G protein-coupled receptpr kinase 1; GPRK1; G-protein coupled receptor kinase 1; G-protein receptor kinase 1; GRK 1a/b; GRK1; GRK1a; rhodopsin kinase; rhodopsin kinase GRK1; Rhok; RK
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
24013, 281457, 395431, 6011, 81760
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: GRK1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: antibody with 0.05% sodium azide
Gene Accession No.: P28327, Q15835, Q9WVL4
Gene Symbols: GRK1
Immunogen: Full length human GRK1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: D11
Conjugate: Unconjugated
Gene: GRK1
Gene Alias: G protein-coupled receptor kinase 1; G protein-coupled receptpr kinase 1; GPRK1; G-protein coupled receptor kinase 1; G-protein receptor kinase 1; GRK 1a/b; GRK1; GRK1a; rhodopsin kinase; rhodopsin kinase GRK1; Rhok; RK
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 24013, 281457, 6011
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
GRK1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
antibody with 0.05% sodium azide
Gene Accession No.:
P28327, Q15835, Q9WVL4
Gene Symbols:
GRK1
Immunogen:
Full length human GRK1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
D11
Conjugate:
Unconjugated
Gene:
GRK1
Gene Alias:
G protein-coupled receptor kinase 1; G protein-coupled receptpr kinase 1; GPRK1; G-protein coupled receptor kinase 1; G-protein receptor kinase 1; GRK 1a/b; GRK1; GRK1a; rhodopsin kinase; rhodopsin kinase GRK1; Rhok; RK
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
24013, 281457, 6011
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: RGS9
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: O46469, O54828
Gene Symbols: RGS9
Immunogen: Full length, bacterially expressed RGS9-1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: D7
Conjugate: Unconjugated
Gene: RGS9
Gene Alias: GTPase accelerating protein for heterotrimeric G-proteins; MGC111763; MGC26458; PERRS; regulator of G protein signaling 9; regulator of G protein signaling 9; regulator of G-protein signaling 9; regulator of G-protein signaling 9; regulator of G-protein signalling 9; Rgs9; RGS9-1; Rgs9-2; RGS9L; ROS GAP
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 19739, 281453
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
RGS9
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
O46469, O54828
Gene Symbols:
RGS9
Immunogen:
Full length, bacterially expressed RGS9-1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
D7
Conjugate:
Unconjugated
Gene:
RGS9
Gene Alias:
GTPase accelerating protein for heterotrimeric G-proteins; MGC111763; MGC26458; PERRS; regulator of G protein signaling 9; regulator of G protein signaling 9; regulator of G-protein signaling 9; regulator of G-protein signaling 9; regulator of G-protein signalling 9; Rgs9; RGS9-1; Rgs9-2; RGS9L; ROS GAP
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
19739, 281453
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: GCAP1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P43080, P46065
Gene Symbols: Guca1a
Immunogen: Bacterial expressed full length GCAP-1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Human, Non-human Primate
Product Type: Antibody
Isotype: IgG2a
Applications: Western Blot
Clone: G2
Conjugate: Unconjugated
Gene: Guca1a
Gene Alias: C6orf131; COD3; cone dystrophy 3; CORD14; GC-A; GCAP; GCAP 1; GCAP1; Guanylate cyclase activator 1A; guanylate cyclase activator 1a (retina); guanylate cyclase-activating protein, photoreceptor 1; guanylin 1, retina; guanylyl cyclase-activating protein; guanylyl cyclase-activating protein 1; GUCA; GUCA1; GUCA1A; mGCAP1
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 282243, 2978
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
GCAP1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P43080, P46065
Gene Symbols:
Guca1a
Immunogen:
Bacterial expressed full length GCAP-1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Western Blot
Clone:
G2
Conjugate:
Unconjugated
Gene:
Guca1a
Gene Alias:
C6orf131; COD3; cone dystrophy 3; CORD14; GC-A; GCAP; GCAP 1; GCAP1; Guanylate cyclase activator 1A; guanylate cyclase activator 1a (retina); guanylate cyclase-activating protein, photoreceptor 1; guanylin 1, retina; guanylyl cyclase-activating protein; guanylyl cyclase-activating protein 1; GUCA; GUCA1; GUCA1A; mGCAP1
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
282243, 2978
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid