MA3014

HSC70 Monoclonal Antibody (13D3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA3014-Each-of-1 In Stock ₹ 46,245.18

MA3014 - Each of 1

₹ 46,245.18

In Stock

Quantity

1

Base Price: ₹ 46,245.18

GST (18%): ₹ 8,324.132

Total Price: ₹ 54,569.312

Antigen

HSC70

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P11142, P63017, P63018

Gene Symbols

Hspa8

Immunogen

Mouse spermatogenic cell protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Feline, Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgM

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone

13D3

Conjugate

Unconjugated

Gene

Hspa8

Gene Alias

2410008N15Rik; AAG2; constitutive heat shock protein 70; constitutively expressed heat shock protein; epididymis luminal protein 33; epididymis secretory sperm binding protein Li 72p; FAM10A1; Heat shock 70 kDa protein 8; heat shock 70kd protein 10; heat shock 70kd protein 10 (HSC71); heat shock 70kD protein 8; heat shock 70kDa protein 8; heat shock cognate; heat shock cognate 70; heat shock cognate 71 kD protein; heat shock cognate 71 kDa protein; heat shock cognate 71 kDa protein-like protein; heat shock cognate 71-kd protein; heat shock cognate hsc73; heat shock cognate protein 54; Heat shock cognate protein 70; heat shock protein 70 cognate; heat shock protein 8; heat shock protein A8; heat shock protein cognate 70; heat shock protein family A (Hsp70) member 8; HEL-33; HEL-S-72p; HIP; HSC54; Hsc70; Hsc70 ATPase; HSC70 protein; Hsc71; Hsc73; HSP70; HSP71; HSP73; Hspa10; Hspa8; hspa8 protein; I79_022974; LAP; LAP1; LAP-1; lipopolysaccharide-associated protein 1; LPS-associated protein 1; MGC131511; MGC29929; NIP71; N-myristoyltransferase inhibitor protein 71; Protein FAM10A1; similar to 7O KDa heat shock cognate protein; SNC6; unnamed protein product; wu:fb01g06; wu:fi48b06

Host Species

Mouse

Purification Method

Affinity chromatography - MBP

Regulatory Status

RUO

Gene ID (Entrez)

101087422, 15481, 24468, 3312

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Thermo Scientific

MA110890

--

Img

Thermo Scientific

MA3028

--

Img

Thermo Scientific

PA1014A

--

Img

Thermo Scientific

MA3013

--

Img

Thermo Scientific

PA129794

--

Img

Thermo Scientific

PA1017

--

Img

Thermo Scientific

MA3012

--

Img

Thermo Scientific

PA1018

--

Description

  • MA3-014 detects heat shock cognate protein 70 kDa (HSC70) from human, feline, primate, rat, and mouse tissues
  • This antibody displays slight cross-reactivity to HSP70
  • MA3-014 has been successfully used in Western blot, immunohistochemistry, immunofluorescence, and immunoprecipitation procedures By Western blot, this antibody detects a 70 kDa protein representing HSC70
  • By 2D gel electrophoresis, MA3-014 was found to bind strongly to HSC70 and faintly to HSP70 both before and after heat shock
  • Immunohistochemical staining of HSC70 in mouse spermatids/spermatozoa with MA3-014 results in staining restricted to the post acrosomal region in condensing spermatids and to the midpiece in spermatozoa
  • The MA3-014 antigen is mouse spermatogenic cell protein
  • The HSP70 family is a set of highly conserved proteins that are induced by a variety of biological stresses, including heat stress, in every organism in which the proteins have been examined
  • The human HSP70 family members include: HSP70, a protein which is strongly inducible in all organisms but which is also constitutively expressed in primate cells; HSP72, a 72 kDa protein that is induced exclusively under stress conditions; HSC70, or cognate protein, is a 72 kDa, constitutively expressed, protein which is involved in the uncoating of clathrin coated vesicles; GRP78, or BiP, is a glucose regulated 78 kDa protein localized in the endoplasmic reticulum; and p75, or HSP75, a 75 kDa protein that is found within the mitochondria
  • HSC70 (also known as HSC71, HSC73, HSP73, p72, prp73) is expressed constitutively and is slightly heat-inducible
  • HSC70 binds to the exposed loop of clathrin light chains to promote uncoating and can also bind the cytoskeleton which may facilitate cytoskeletal rearrangements
  • HSC70 has been shown to stimulate lysosomal degradation of intracellular proteins and to retard both aggregation and folding of mitochondrial precursor proteins in vitro.

Compare Similar Items

Show Difference

Img

Thermo Scientific

MA3014

--


Antigen:
HSC70

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P11142, P63017, P63018

Gene Symbols:
Hspa8

Immunogen:
Mouse spermatogenic cell protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Feline, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
13D3

Conjugate:
Unconjugated

Gene:
Hspa8

Gene Alias:
2410008N15Rik; AAG2; constitutive heat shock protein 70; constitutively expressed heat shock protein; epididymis luminal protein 33; epididymis secretory sperm binding protein Li 72p; FAM10A1; Heat shock 70 kDa protein 8; heat shock 70kd protein 10; heat shock 70kd protein 10 (HSC71); heat shock 70kD protein 8; heat shock 70kDa protein 8; heat shock cognate; heat shock cognate 70; heat shock cognate 71 kD protein; heat shock cognate 71 kDa protein; heat shock cognate 71 kDa protein-like protein; heat shock cognate 71-kd protein; heat shock cognate hsc73; heat shock cognate protein 54; Heat shock cognate protein 70; heat shock protein 70 cognate; heat shock protein 8; heat shock protein A8; heat shock protein cognate 70; heat shock protein family A (Hsp70) member 8; HEL-33; HEL-S-72p; HIP; HSC54; Hsc70; Hsc70 ATPase; HSC70 protein; Hsc71; Hsc73; HSP70; HSP71; HSP73; Hspa10; Hspa8; hspa8 protein; I79_022974; LAP; LAP1; LAP-1; lipopolysaccharide-associated protein 1; LPS-associated protein 1; MGC131511; MGC29929; NIP71; N-myristoyltransferase inhibitor protein 71; Protein FAM10A1; similar to 7O KDa heat shock cognate protein; SNC6; unnamed protein product; wu:fb01g06; wu:fi48b06

Host Species:
Mouse

Purification Method:
Affinity chromatography - MBP

Regulatory Status:
RUO

Gene ID (Entrez):
101087422, 15481, 24468, 3312

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3016

--


Antigen:
GRP94

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
P08110, P08113, P14625, Q66HD0, Q95M18

Gene Symbols:
HSP90B1

Immunogen:
Chick oviduct GRP94.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Chicken, Hamster, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
9G10

Conjugate:
Unconjugated

Gene:
HSP90B1

Gene Alias:
108K heat shock protein; 108K HSP; 94 kDa glucose-regulated protein; 94 kDa glucose-regulated protein {ECO:0000250; 98 kDa protein kinase; ecgp; endoplasmic reticulum resident protein 99; Endoplasmin; endoplasmin {ECO:0000250; endoplasmin-like protein; endothelial cell (HBMEC) glycoprotein; epididymis luminal protein 35; epididymis secretory sperm binding protein Li 125m; ERp99; glucose-regulated protein; glucose-regulated protein GRP94; glucose-regulated protein GRP94 precursor; GP96; gp96 homolog; gp96/GRP94; GRP94; GRP-94; heat shock 108 kDa protein; heat shock protein 108; heat shock protein 108.; heat shock protein 90 beta family member 1; heat shock protein 90 kDa beta member 1; heat shock protein 90 kDa beta member 1 {ECO:0000250; heat shock protein 90, beta (Grp94), member 1; heat shock protein 90, beta, member 1; heat shock protein 90kDa beta (Grp94), member 1; heat shock protein 90kDa beta family member 1; heat shock protein 90kDa beta family member 1 L homeolog; heat shock protein 90kDa beta, member 1; heat shock protein gp96; HEL35; HEL-S-125m; HSP 108; hsp108; HSP90 beta; hsp90b1; hsp90b1 {ECO:0000250; hsp90b1.L; Polymorphic tumor rejection antigen 1; PPK 98; Ppk 98; a protein kinase; ppk98; stress-inducible tumor rejection antigen gp96; TA-3; Targ2; tra1; Tra-1; transferrin-binding protein; transforming growth factor alpha regulated gene 2; tumor rejection antigen; tumor rejection antigen (gp96) 1; tumor rejection antigen 1; Tumor rejection antigen gp96; UniProtKB:P08113}; XELAEV_18017384mg

Host Species:
Rat

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
100773331, 22027, 282646, 362862, 374163, 7184

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3017

--


Antigen:
CRABP2

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
P29373

Gene Symbols:
CRABP2

Immunogen:
recombinant protein corresponding to full length human CRABPII

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Immunocytochemistry, Western Blot

Clone:
5CRA-3B3

Conjugate:
Unconjugated

Gene:
CRABP2

Gene Alias:
AI893628; cellular lipid-binding protein; cellular retinoic acid binding protein 2; cellular retinoic acid binding protein II; cellular retinoic acid-binding protein 2; Cellular retinoic acid-binding protein II; Crabp2; Crabp-2; CrabpII; CRABP-II; RBP6; RP11-66D17.4

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
1382

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA3018

--


Antigen:
PDI

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites diluted in PBS with 0.05% sodium azide

Gene Accession No.:
P04785, P07237, P09103, Q8R4U2

Gene Symbols:
P4hb, p4hb.L, pdia2.L

Immunogen:
Purified rat PDI protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Hamster, Human, Mouse, Porcine, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
RL77

Conjugate:
Unconjugated

Gene:
P4hb

Gene Alias:
1810041F13Rik; AI661267; CaO19.12595; cellular thyroid hormone binding protein; cellular thyroid hormone-binding protein; CLCRP1; collagen prolyl 4-hydroxylase beta; DSI; Endoplasmic reticulum resident protein 59; Eps1p; ER protein 59; ERBA2L; ERp59; GIT; glutathione-insulin transhydrogenase; I79_002399; LOW QUALITY PROTEIN: protein disulfide-isomerase A2; MFP1; P4HB; p4hb.L; P4Hbeta; p55; p58; Pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; PDA2; PDI; PDI (E.C.5.3.4.1); PDI1; PDI1P; Pdia1; pdia2; pdia2.L; PDIP; Pdipl; PDIR; PHDB; PO4DB; PO4HB; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; PROHB; prolyl 4-hydroxylase beta polypeptide; Prolyl 4-hydroxylase subunit beta; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase, beta polypeptide L homeolog; prolyl 4-hydroxylase, beta polypeptide; prolyl 4-hydroxylase, beta subunit; protein disulfide isomerase; protein disulfide isomerase (pancreas) like; Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide); protein disulfide isomerase A2; protein disulfide isomerase associated 2; protein disulfide isomerase family A member 2; protein disulfide isomerase family A member 2 L homeolog; protein disulfide isomerase family A, member 1; protein disulfide isomerase family A, member 2; protein disulfide isomerase PDI1; protein disulfide isomerase, pancreatic; protein disulfide isomerase/oxidoreductase; protein disulfide isomerase-associated 1; protein disulfide isomerase-associated 2; protein disulfide-isomerase; Protein disulfide-isomerase A2; protocollagen hydroxylase; Rho GDP dissociation inhibitor gamma; testicular secretory protein Li 32; Thbp; Thioredoxin-related glycoprotein 1; thyroid hormone-binding protein p55; TRG1; XELAEV_18043753mg; XELAEV_18045582mg; XPDIp; YCL043C; YCL313; YCL43C

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
100689433, 110255932, 18453, 25506, 399040, 399248, 483369, 5034

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid