MAB1618AF55

MilliporeSigma™ Mouse anti-Dynein, Clone: 74.1, Alexa Fluor 555,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MAB1618AF55-Each-of-1 In Stock ₹ 40,196.94

MAB1618AF55 - Each of 1

₹ 40,196.94

In Stock

Quantity

1

Base Price: ₹ 40,196.94

GST (18%): ₹ 7,235.449

Total Price: ₹ 47,432.389

Antigen

Dynein

Classification

Monoclonal

Conjugate

Alexa Fluor 555

Gene Accession No.

Q29RQ3; Q0III3

Host Species

Mouse

Purification Method

Protein A Purfied

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Bovine, Drosophila, Fish, Human, Mouse, Rat, Sheep, Xenopus species

Form

Purified

Applications

Immunocytochemistry

Clone

74.1

Formulation

Purified mouse monoclonal IgG2b antibody conjugate in PBS with 15mg/mL BSA and 0.1% sodium azide.

Gene Symbols

DYNC1I1; DYNC1I2

Immunogen

Bovine brain cytoplasmic dynein.

Quantity

100 μL

Research Discipline

Cell Structure

Gene ID (Entrez)

NM_012144.2

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2b

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Description

  • Specifically detects Dynein clone: 74.1 in Bovine, Drosophila, Fish, Human, Mouse, Rat, Sheep, Xenopus samples, and it is validated for Immunocytochemistry Cytoplasmic dynein 1 intermediate chain 1 (UniProt Q29RQ3; also known as Cytoplasmic dynein intermediate chain 1, Dynein intermediate chain 1, cytosolic, DH IC-1) and Cytoplasmic dynein 1 intermediate chain 2 (UniProt Q0III3; also known as Cytoplasmic dynein intermediate chain 2, Dynein intermediate chain 2, cytosolic, DH IC-2) are encoded by the DYNC1I1 gene (Gene ID 613724) and DYNC1I2 gene (Gene ID 526329) in bovine, respectively
  • Cytoplasmic dynein complexes are microtubules-associated retrograde transport motors
  • Cytoplasmic dynein 1 is the more abundant motor in cells, while cytoplasmic dynein 2 takes part in intraflagellar transport
  • Cytoplasmic dynein 1 is a multisubunit complex of ∼1.5 MDa composed of a homodimer of heavy chains (encoded by DYNC1H1), two intermediate chains (encoded by DYNC1I1 and DYNC1I2), light-intermediate chains (encoded by DYNC1LI1, DYNC1LI2) and light chains (encoded by DYNLT1, DYNLT3, DYNLRB1, DYNLRB2, DYNLL1, DYNLLl2)
  • The heavy chain homodimer acts as the dynein complex core and binds microtubules to enable ATP-dependent cytoplasmic dynein movement
  • The other dynein subunits associate as homodimers and play regulatory roles in maintaining the complex stability, modulating its activity, and mediating its interaction with accessory and cargo proteins
  • The intermediate chain proteins (IC1 & IC2) are involved in cargo binding and specificity, either alone or via interaction with the dynactin complex
  • IC1 and IC2 share 69% protein identity
  • They interact with the dynein light chains and the p150 subunit of dynactin at the N-terminus and with the heavy chains through WD40 repeats at the intermediate chain C-terminus.

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Show Difference

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MilliporeSigma™

MAB1618AF55

--


Antigen:
Dynein

Classification:
Monoclonal

Conjugate:
Alexa Fluor 555

Gene Accession No.:
Q29RQ3; Q0III3

Host Species:
Mouse

Purification Method:
Protein A Purfied

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Bovine, Drosophila, Fish, Human, Mouse, Rat, Sheep, Xenopus species

Form:
Purified

Applications:
Immunocytochemistry

Clone:
74.1

Formulation:
Purified mouse monoclonal IgG2b antibody conjugate in PBS with 15mg/mL BSA and 0.1% sodium azide.

Gene Symbols:
DYNC1I1; DYNC1I2

Immunogen:
Bovine brain cytoplasmic dynein.

Quantity:
100 μL

Research Discipline:
Cell Structure

Gene ID (Entrez):
NM_012144.2

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b

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MilliporeSigma™

MAB1618AF64

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Antigen:
Dynein

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Gene Accession No.:
Q29RQ3; Q0III3

Host Species:
Mouse

Purification Method:
Protein A Purfied

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Bovine, Drosophila, Fish, Human, Mouse, Rat, Sheep, Xenopus species

Form:
Purified

Applications:
Immunocytochemistry

Clone:
74.1

Formulation:
Purified mouse monoclonal IgG2b antibody conjugate in PBS with 15mg/mL BSA and 0.1% sodium azide.

Gene Symbols:
DYNC1I1; DYNC1I2

Immunogen:
Bovine brain cytoplasmic dynein.

Quantity:
100 μL

Research Discipline:
Cell Structure

Gene ID (Entrez):
NM_012144.2

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b

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Fischer Scientific

MAB1619

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Antigen:
IL-23A/IL-23 P19

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
P43432 (p40) & Q9EQ14 (p19)

Host Species:
Rat

Purification Method:
Protein A or G purified from hybridoma culture supernatant

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

Applications:
Western Blot

Clone:
320229

Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative

Gene Symbols:
IL23A

Immunogen:
E. coli-derived recombinant mouse IL-23 p19 andS. frugiperdainsect ovarian cell lineSf21-derived recombinant mouse IL-23 heterodimers Met23-Ser335 (p40) & Leu20-Ala196 (p19) Accession # P43432 (p40) & Q9EQ14 (p19)

Quantity:
500 μg

Research Discipline:
__

Gene ID (Entrez):
51561

Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Isotype:
IgG2a

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MAB1619SP

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Antigen:
IL-23A/IL-23 P19

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
P43432 (p40) & Q9EQ14 (p19)

Host Species:
Rat

Purification Method:
Protein A or G purified from hybridoma culture supernatant

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

Applications:
Western Blot

Clone:
320229

Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative

Gene Symbols:
IL23A

Immunogen:
E. coli-derived recombinant mouse IL-23 p19 andS. frugiperdainsect ovarian cell lineSf21-derived recombinant mouse IL-23 heterodimers Met23-Ser335 (p40) & Leu20-Ala196 (p19) Accession # P43432 (p40) & Q9EQ14 (p19)

Quantity:
25 μg

Research Discipline:
__

Gene ID (Entrez):
51561

Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Isotype:
IgG2a