MAB374AF488

MilliporeSigma™ Mouse anti-GAPDH, Clone: 6C5, Alexa Fluor 488,

Manufacturer: MilliporeSigma™

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Pack Size SKU Availability Price
Each of 1 MAB374AF488-Each-of-1 In Stock ₹ 41,643.76

MAB374AF488 - Each of 1

₹ 41,643.76

In Stock

Quantity

1

Base Price: ₹ 41,643.76

GST (18%): ₹ 7,495.877

Total Price: ₹ 49,139.637

Antigen

GAPDH

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Gene Accession No.

P46406

Host Species

Mouse

Purification Method

Protein A Purfied

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Purified

Applications

Immunocytochemistry

Clone

6C5

Formulation

Purified mouse conjugate antibody in buffer containing PBS 15mg/mL BSA and 0.1% Sodium Azide.

Gene Symbols

GAPDH; GAPD

Immunogen

Glyceraldehyde-3-phosphate dehydrogenase from rabbit muscle.

Quantity

100 μL

Research Discipline

Signaling

Gene ID (Entrez)

NM_001082253.1

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG1

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Description

  • Specifically detects GAPDH clone: 6C5 in Human, Mouse samples, and it is validated for Immunocytochemistry Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is an ubiquitous glycolytic enzyme present in reasonably high levels in almost all tissues
  • The complete and functional enzyme is a tetramer with each of four identical subunits occupying the vertex of a tetrahedron
  • Its binding domains also include one principally interacting with NAD + and another interacting with glyceraldehyde 3-phosphate (GAP)
  • As a 'house-keeping' enzyme, it catalyzes the synthesis of 1,3-biphosphoglycerate, a 'high energy' intermediate used for the synthesis of ATP
  • Besides its cytoplasmic role in metabolism, it is also involved in the initial stages of apoptosis or oxidative stress response where it is translocated to the nucleus
  • Such actions may reflect the role of GAPDH in DNA repair or as one nuclear carrier for apoptotic molecules
  • GAPDH can also bind specifically to proteins implicated in the pathogenesis of a variety of neurodegenerative disorders, including the beta-amyloid precursor protein and the Huntingtin protein where reduced function of GAPDH is associated with Alzheimer's and Huntington's disease fibroblasts
  • GAPDH has also been identified as a potential target for nitric oxide (NO)-mediated cellular toxicity.

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Img

MilliporeSigma™

MAB374AF488

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Antigen:
GAPDH

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene Accession No.:
P46406

Host Species:
Mouse

Purification Method:
Protein A Purfied

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified

Applications:
Immunocytochemistry

Clone:
6C5

Formulation:
Purified mouse conjugate antibody in buffer containing PBS 15mg/mL BSA and 0.1% Sodium Azide.

Gene Symbols:
GAPDH; GAPD

Immunogen:
Glyceraldehyde-3-phosphate dehydrogenase from rabbit muscle.

Quantity:
100 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NM_001082253.1

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1

Img

MilliporeSigma

MAB374MI

--


Antigen:
Glyceraldehyde-3-Phosphate Dehydrogenase

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
NP_002037

Host Species:
Mouse

Purification Method:
Protein A purfied

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Canine, Feline, Fish, Human, Mouse, Porcine, Rabbit, Rat

Form:
Purified

Applications:
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
6C5

Formulation:
Purified Mouse monoclonal IgG1 in PBS, pH 7.4 with 0.1% sodium azide.

Gene Symbols:
GAPDH, G3PDH, GAPD, G3PD

Immunogen:
Glyceraldehyde-3-phosphate dehydrogenase from rabbit muscle.

Quantity:
200 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C in undiluted aliquots for up to 6 months.

Isotype:
IgG1

Img

MilliporeSigma

MAB3750MI

--


Antigen:
LEF-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
NM_016269.2

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
1C3.1D10

Formulation:
Purified immunoglobulin. Provided as solution in phosphate buffered saline with 0.08% sodium azide.

Gene Symbols:
LEF1, LEF-1, TCF1-alpha, TCF1ALPHA, DKFZp586H0919

Immunogen:
Recombinant full length LEF-1 protein.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
−20°C in undiluted aliquots for 12 months. Avoid repeated freeze/thaw cycles.

Isotype:
IgG1

Img

Fischer Scientific

MAB375100

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Antigen:
TRAIL/TNFSF10

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
P50591

Host Species:
Mouse

Purification Method:
Protein A or G purified from ascites

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry, Neutralization

Clone:
75411

Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative

Gene Symbols:
TNFSF10

Immunogen:
Mouse myeloma cell line NS0-derived recombinant human TRAIL/TNFSF10 Thr95-Gly281 Accession # P50591

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
8743

Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Isotype:
IgG1