MABE928MI
MilliporeSigma™ Mouse anti-N-methylpurine-DNA glycosylase, Clone: 9F7.1,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE928MI-Each-of-1 | In Stock | ₹ 36,371.63 |
MABE928MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,371.63
GST (18%): ₹ 6,546.893
Total Price: ₹ 42,918.523
Antigen
N-methylpurine-DNA glycosylase
Classification
Monoclonal
Formulation
Mouse monoclonal IgG1κ cell culture supernatant without preservatives.
Gene Symbols
MPG; AAG; ANPG; MID1
Immunogen
GST-tagged recombinant protein corresponding to human N-methylpurine-DNA glycosylase near the N-terminus.
Quantity
100 μL
Research Discipline
Epigenetics and Nuclear Function
Gene ID (Entrez)
NP_001015052
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype
IgG1 κ
Applications
Immunocytochemistry, Western Blot
Clone
9F7.1
Gene Accession No.
P29372
Host Species
Mouse
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Supernatant
Related Products
Description
- Specifically detects N-methylpurine-DNA glycosylase clone: 9F7.1 in Human samples, and it is validated for Immunocytochemistry, Western Blotting N-methylpurine-DNA glycosylase (also known as 3-alkyladenine DNA glycosylase, 3-methyladenine DNA glycosidase, ADPG, DNA-3-methyladenine glycosylase) is encoded by the MPG (also called AAG, ANPG, MID1) gene in human (NCBI Gene ID 4350)
- MPG/AAG protein is involved in repair of DNA damage due to alkylation both in the nucleus and mitochondria
- Specifically, MPG/AAG protein catalyzes the hydrolysis of the N-glycosyl bond between the alkylated base and deoxyribose, thereby removing 3-methyladenine and 7-methylguanine to form 'abasic sites' in the damaged DNA
- MPG/AAG protein is also found to exhibit DNA-O-glycosidase activity
- MPG/AAG protein is reported to remain associated with the abasic DNA after base removal and, in the presence of small alcohols, catalyze the formation of an O-glycosidic linkage between the alcohol hydroxyl group and C1' of the abasic deoxyribose
- Unpon alcohol removal, MPG/AAG protein is shown to catalyze the reverse reaction by hydrolyzing the O-glycosidic bonds of alcohol-DNA adducts
- (PMID 23290262 & 23688261)
- Clone 9F7.1 detects an epitope within human MPG/AAG protein (UniProt P29372) N-terminal region, which is not well conserved in murine protein (UniProt Q04841).
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Antigen: N-methylpurine-DNA glycosylase
Classification: Monoclonal
Formulation: Mouse monoclonal IgG1κ cell culture supernatant without preservatives.
Gene Symbols: MPG; AAG; ANPG; MID1
Immunogen: GST-tagged recombinant protein corresponding to human N-methylpurine-DNA glycosylase near the N-terminus.
Quantity: 100 μL
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_001015052
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG1 κ
Applications: Immunocytochemistry, Western Blot
Clone: 9F7.1
Gene Accession No.: P29372
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Supernatant
Antigen:
N-methylpurine-DNA glycosylase
Classification:
Monoclonal
Formulation:
Mouse monoclonal IgG1κ cell culture supernatant without preservatives.
Gene Symbols:
MPG; AAG; ANPG; MID1
Immunogen:
GST-tagged recombinant protein corresponding to human N-methylpurine-DNA glycosylase near the N-terminus.
Quantity:
100 μL
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_001015052
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Western Blot
Clone:
9F7.1
Gene Accession No.:
P29372
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Supernatant
Antigen: Tudor-SN
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: SND1, TDRD11
Immunogen: Recombinant protein corresponding to the C-terminus of human Tudor-SN.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: Western Blot
Clone: 13.14.1
Gene Accession No.: NP_055205
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Tudor-SN
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
SND1, TDRD11
Immunogen:
Recombinant protein corresponding to the C-terminus of human Tudor-SN.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
13.14.1
Gene Accession No.:
NP_055205
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: ASF-1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: SRSF1, ASF, SF2, SF2P33, SFRS1
Immunogen: Recombinant protein corresponding to human ASF-1.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG2b κ
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: AK-96
Gene Accession No.: NP_001071634
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
ASF-1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
SRSF1, ASF, SF2, SF2P33, SFRS1
Immunogen:
Recombinant protein corresponding to human ASF-1.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2b κ
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
AK-96
Gene Accession No.:
NP_001071634
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: phospho Histone H3 (Ser10)
Classification: Monoclonal
Formulation: Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: H3F3A, H3.3A, H3F3
Immunogen: KLH-conjugated linear peptide corresponding to human Histone H3 (Ser10).
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG2a κ
Applications: Immunocytochemistry, Western Blot
Clone: 6G8B7
Gene Accession No.: NP_002098
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
phospho Histone H3 (Ser10)
Classification:
Monoclonal
Formulation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
H3F3A, H3.3A, H3F3
Immunogen:
KLH-conjugated linear peptide corresponding to human Histone H3 (Ser10).
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Western Blot
Clone:
6G8B7
Gene Accession No.:
NP_002098
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified