MABF1680

MilliporeSigma™ Mouse anti-CD8a, Clone: RPA-T8, PE,

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MABF1680-Each-of-1 In Stock ₹ 18,768.44

MABF1680 - Each of 1

₹ 18,768.44

In Stock

Quantity

1

Base Price: ₹ 18,768.44

GST (18%): ₹ 3,378.319

Total Price: ₹ 22,146.759

Antigen

CD8a

Classification

Monoclonal

Conjugate

PE

Gene Accession No.

P01732

Host Species

Mouse

Purification Method

Purified by size-exclusion chromatography

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

RPA-T8

Formulation

Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.

Gene Symbols

CD8A; MAL

Immunogen

Immunogen information for this antibody is proprietary information.

Quantity

100 Tests

Research Discipline

Inflammation and Immunology

Target Species

Human

Form

Purified

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Description

  • Specifically detects CD8a clone: RPA-T8 in Human samples, and it is validated for Flow Cytometry The RPA-T8 antibody is specific for the 32-34kDa alpha chain of human CD8, known as CD8a or CD8 alpha
  • CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta
  • CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules
  • The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions
  • CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.The RPA-T8 antibody is widely used as a phenotypic marker for CD8 on cytotoxic T cells, thymocytes, as well as on certain cell types that do not also express the TCR, including some NK cells and lymphoid dendritic cells
  • It is cross-reactive with CD8 in several non-human species, including Baboon, Chimpanzee, Cynomolgus and Rhesus
  • If used together with an alternative Anti-Human CD8a clone, Hit8a, the RPA-T8 antibody will not block binding of Hit8a to CD8a.

Compare Similar Items

Show Difference

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Fischer Scientific

MABF1680

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Antigen:
CD8a

Classification:
Monoclonal

Conjugate:
PE

Gene Accession No.:
P01732

Host Species:
Mouse

Purification Method:
Purified by size-exclusion chromatography

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
RPA-T8

Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.

Gene Symbols:
CD8A; MAL

Immunogen:
Immunogen information for this antibody is proprietary information.

Quantity:
100 Tests

Research Discipline:
Inflammation and Immunology

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

MABF1681

--


Antigen:
CD8a

Classification:
Monoclonal

Conjugate:
PE

Gene Accession No.:
P01732

Host Species:
Mouse

Purification Method:
Purified by size-exclusion chromatography

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
RPA-T8

Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.

Gene Symbols:
CD8A; MAL

Immunogen:
Immunogen information for this antibody is proprietary information.

Quantity:
500 Tests

Research Discipline:
Inflammation and Immunology

Target Species:
Human

Form:
Purified

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