MABF172B

Anti-CD4 (human), PerCP, clone SK3 Antibody

clone SK3, from mouse, Peridinin-Chlorophyll-Protein Complex

Manufacturer: Sigma Aldrich

Synonym(S): T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD antigen CD4, CD4

Select a Size

Pack Size SKU Availability Price
25 TESTS MABF172B-25-TESTS In Stock ₹ 24,340.00
100 TESTS MABF172B-100-TESTS In Stock ₹ 57,670.00
500 TESTS MABF172B-500-TESTS In Stock ₹ 2,60,030.00

MABF172B - 25 TESTS

₹ 24,340.00

In Stock

Quantity

1

Base Price: ₹ 24,340.00

GST (18%): ₹ 4,381.20

Total Price: ₹ 28,721.20

biological source

mouse

Quality Level

100

conjugate

Peridinin-Chlorophyll-Protein Complex

antibody form

purified antibody

antibody product type

primary antibodies

clone

SK3, monoclonal

species reactivity

human

technique(s)

flow cytometry: suitable

UniProt accession no.

P01730

target post-translational modification

unmodified

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Description

  • General description: The SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.
  • Immunogen: Immunogen information for this antibody is proprietary information.
  • Application: Anti-CD4 (human), PerCP, clone SK3 Antibody is an antibody against CD4 for use in Flow Cytometry.
  • Quality: This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.Flow Cytometry Analysis: 0.06 μg from a representative lot detected CD4 in one million human peripheral blood lymphocytes.
  • Physical form: Purified Mouse monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
  • Storage and Stability: Stable for 1 year at 2-8°C from date of receipt.Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
  • Other Notes: Concentration: Please refer to lot specific datasheet.
  • Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

SAFETY INFORMATION

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