MABF2005100
CCR5 (CD195), Rat anti-Human, Clone: HEK/1/85a/7a, Millipore Sigma™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF2005100-Each-of-1 | In Stock | ₹ 41,308.37 |
MABF2005100 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,308.37
GST (18%): ₹ 7,435.507
Total Price: ₹ 48,743.877
Antigen
CCR5 (CD195)
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
Purified rat monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
CCR5;CMKBR5
Immunogen
CHO cells transfected with full length human CCR-5 (CD195).
Quantity
100 μg
Research Discipline
Inflammation & Immunology
Gene ID (Entrez)
NP_000570.1
Target Species
Human
Form
Purified
Applications
Flow Cytometry, Immunocytochemistry
Clone
HEK/1/85a/7a
Dilution
Immunocytochemistry Analysis: A representative lot detected CCR5 (CD195) in Immunocytochemistry applications (Mueller, A., et. al. (2002). Blood. 99(3):785-91).Flow Cytometry Analysis: A representative lot detected CCR5 (CD195) in Flow Cytometry applications (Mueller, A., et. al. (2002). Blood. 99(3):785-91).
Gene Alias
C-C chemokine receptor type 5;C-C CKR-5;CC-CKR-5;CCR-5;CCR5;CHEMR13;HIV-1 fusion coreceptor;CD195
Host Species
Rat
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone HEK/1/85a/7a is a rat monoclonal antibody that specifically detects human C-C-chemokine receptor 5 (CD195).
Content And Storage
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype
IgG2b κ
Related Products
Description
- Anti-CCR5 (CD195), clone HEK/1/85a/7a, Cat
- No
- MABF2005, is a rat monoclonal antibody that detects C-C chemokine receptor type 5 (CCR5) and has been tested for use in Flow Cytometry and Immunocytochemistry
- C-C chemokine receptor type 5 (UniProt: P51681; also known as C-C CKR-5, CC-CKR-5, CCR-5, CCR5, CHEMR13, HIV-1 fusion coreceptor, CD195) is encoded by the CCR5 (also known as CMKBR5) gene (Gene ID: 1234) in human
- CCR-5 is a multi-pass membrane protein that is expressed in memory T-cells, macrophages, and immature dendritic cells, and is upregulated by proinflammatory cytokines
- It is also shown to be highly expressed in spleen, thymus, and on THP-1 and KG-1a cells
- Lower expression is observed in ovary and lung
- CCR-5 serves as a receptor for a number of inflammatory CC-chemokines and subsequently transduces a signal by increasing intracellular calcium levels
- It also plays a role in the control of granulocytic lineage proliferation or differentiation
- CCR-5 is acts as a co-receptor (CD4 being the primary receptor) of HIV-1 and HIV-2
- It also couples to Gi class of G-proteins to inhibit cAMP production and stimulate calcium release
- CCR-5 undergoes sulfation on two tyrosine residues in the N-terminal region, which increases efficiency of HIV-1 entry into cells
- It also undergoes phosphorylation at C-terminal serine residues following binding to CC chemokines, especially APO-RANTES
- Mutations in CCR5 gene have been linked to insulin-dependent diabetes mellitus
- (Ref.: Blanpain, C., et al
- (2002)
- Receptors Channels
- 8(1);19-31).
Compare Similar Items
Show Difference
Antigen: CCR5 (CD195)
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified rat monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: CCR5;CMKBR5
Immunogen: CHO cells transfected with full length human CCR-5 (CD195).
Quantity: 100 μg
Research Discipline: Inflammation & Immunology
Gene ID (Entrez): NP_000570.1
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry
Clone: HEK/1/85a/7a
Dilution: Immunocytochemistry Analysis: A representative lot detected CCR5 (CD195) in Immunocytochemistry applications (Mueller, A., et. al. (2002). Blood. 99(3):785-91).Flow Cytometry Analysis: A representative lot detected CCR5 (CD195) in Flow Cytometry applications (Mueller, A., et. al. (2002). Blood. 99(3):785-91).
Gene Alias: C-C chemokine receptor type 5;C-C CKR-5;CC-CKR-5;CCR-5;CCR5;CHEMR13;HIV-1 fusion coreceptor;CD195
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone HEK/1/85a/7a is a rat monoclonal antibody that specifically detects human C-C-chemokine receptor 5 (CD195).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG2b κ
Antigen:
CCR5 (CD195)
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified rat monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
CCR5;CMKBR5
Immunogen:
CHO cells transfected with full length human CCR-5 (CD195).
Quantity:
100 μg
Research Discipline:
Inflammation & Immunology
Gene ID (Entrez):
NP_000570.1
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry
Clone:
HEK/1/85a/7a
Dilution:
Immunocytochemistry Analysis: A representative lot detected CCR5 (CD195) in Immunocytochemistry applications (Mueller, A., et. al. (2002). Blood. 99(3):785-91).Flow Cytometry Analysis: A representative lot detected CCR5 (CD195) in Flow Cytometry applications (Mueller, A., et. al. (2002). Blood. 99(3):785-91).
Gene Alias:
C-C chemokine receptor type 5;C-C CKR-5;CC-CKR-5;CCR-5;CCR5;CHEMR13;HIV-1 fusion coreceptor;CD195
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone HEK/1/85a/7a is a rat monoclonal antibody that specifically detects human C-C-chemokine receptor 5 (CD195).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG2b κ
Antigen: CCR5 (CD195)
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified rat monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: CCR5;CMKBR5
Immunogen: CHO cells transfected with full length human CCR-5 (CD195).
Quantity: 25 μg
Research Discipline: Inflammation & Immunology
Gene ID (Entrez): NP_000570.1
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry
Clone: HEK/1/85a/7a
Dilution: Immunocytochemistry Analysis: A representative lot detected CCR5 (CD195) in Immunocytochemistry applications (Mueller, A., et. al. (2002). Blood. 99(3):785-91).Flow Cytometry Analysis: A representative lot detected CCR5 (CD195) in Flow Cytometry applications (Mueller, A., et. al. (2002). Blood. 99(3):785-91).
Gene Alias: C-C chemokine receptor type 5;C-C CKR-5;CC-CKR-5;CCR-5;CCR5;CHEMR13;HIV-1 fusion coreceptor;CD195
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone HEK/1/85a/7a is a rat monoclonal antibody that specifically detects human C-C-chemokine receptor 5 (CD195).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG2b κ
Antigen:
CCR5 (CD195)
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified rat monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
CCR5;CMKBR5
Immunogen:
CHO cells transfected with full length human CCR-5 (CD195).
Quantity:
25 μg
Research Discipline:
Inflammation & Immunology
Gene ID (Entrez):
NP_000570.1
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry
Clone:
HEK/1/85a/7a
Dilution:
Immunocytochemistry Analysis: A representative lot detected CCR5 (CD195) in Immunocytochemistry applications (Mueller, A., et. al. (2002). Blood. 99(3):785-91).Flow Cytometry Analysis: A representative lot detected CCR5 (CD195) in Flow Cytometry applications (Mueller, A., et. al. (2002). Blood. 99(3):785-91).
Gene Alias:
C-C chemokine receptor type 5;C-C CKR-5;CC-CKR-5;CCR-5;CCR5;CHEMR13;HIV-1 fusion coreceptor;CD195
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone HEK/1/85a/7a is a rat monoclonal antibody that specifically detects human C-C-chemokine receptor 5 (CD195).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG2b κ
Antigen: CD1b
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: CD1B
Immunogen: Isolated human CD1+ monocytes.
Quantity: 25 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): __
Target Species: Human, Guinea Pig
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Inhibition Assays, Neutralization
Clone: __
Dilution: __
Gene Alias: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone BCD1b3.1 detects T-cell surface glycoprotein CD1b in human and guinea pig.
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG1
Antigen:
CD1b
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
CD1B
Immunogen:
Isolated human CD1+ monocytes.
Quantity:
25 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
__
Target Species:
Human, Guinea Pig
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Inhibition Assays, Neutralization
Clone:
__
Dilution:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone BCD1b3.1 detects T-cell surface glycoprotein CD1b in human and guinea pig.
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG1
Antigen: __
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Formulation: __
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Applications: __
Clone: __
Dilution: __
Gene Alias: __
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Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Antigen:
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Classification:
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Formulation:
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Gene Symbols:
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Immunogen:
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Quantity:
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Research Discipline:
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Gene ID (Entrez):
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Target Species:
__
Form:
__
Applications:
__
Clone:
__
Dilution:
__
Gene Alias:
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Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
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Test Specificity:
__
Content And Storage:
__
Isotype:
__