MABF216625

Chlamydial MOMP, Mouse anti-Bacteria, Clone: L21-10, Millipore Sigma™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MABF216625-Each-of-1 In Stock ₹ 16,456.61

MABF216625 - Each of 1

₹ 16,456.61

In Stock

Quantity

1

Base Price: ₹ 16,456.61

GST (18%): ₹ 2,962.19

Total Price: ₹ 19,418.80

Antigen

Chlamydial MOMP

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols

N/A

Immunogen

Formalin killed Chlamydia trachomatis (L2/LGV-434).

Quantity

25 μg

Research Discipline

Inflammation & Immunology

Test Specificity

Clone L21-10 specifically detects outer membrane protein from Chlamydia genus. It displays strong reactivity with serovars D and L3 and weak reactivity with Ba, E, G, L1, and L2.

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG2a λ

Applications

Dot Blot, Immunofluorescence, Immunoprecipitation, Western Blot

Clone

L21-10

Dilution

Immunoprecipitation Analysis: A representative lot immunoprecipiated Chlamydial MOMP in Immunoprecipitation applications (Zhang, Y.X., et. al. (1987). J Immunol. 138(2):575-81).Immunofluorescence Analysis: A representative lot detected Chlamydial MOMP in Immunofluorescence applications (Weber, M.M., et. al. (2017). Cell Rep. 19(7):1406-1417; Zhang, Y.X., et. al. (1987). J Immunol. 138(2):575-81).Western Blotting Analysis: A representative lot detected Chlamydial MOMP in Western Blotting applications (Baehr, W., et. al. (1988). Proc Natl Acad Sci USA. 85(11):4000-4; Zhang, Y.X., et. al. (1987). J Immunol. 138(2):575-81).Dot Blot Analysis: A representative lot detected Chlamydial MOMP in Dot Blot applications (Zhang, Y.X., et. al. (1987). J Immunol. 138(2):575-81).

Gene Alias

Chlamydia major membrane protein

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Bacteria

Form

Purified

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Description

  • Anti-Chlamydial MOMP, clone L21-10, Cat
  • No
  • MABF2166, is a mouse monoclonal antibody that detects Chlamydial major outer membrane protein (MOMP) and has been tested for use in Dot Blot, Immunofluorescence, Immunoprecipitation, and Western Blotting
  • Chlamydia trachomatis is a Gram-negative bacterium that is responsible for sexually transmitted diseases leading to pelvic inflammatory disease, ectopic pregnancy, infertility, and outbreaks of trachoma-associated blindness and lymphogranuloma venereum (LGV)
  • Chlamydia trachomatis consists of eighteen different serological variants (serovars) that include a few subvariants
  • These are identified based on serological reactivity of the epitopes on their outer membrane
  • Intracellularly chlamydia replicates within a vacuole
  • Chlamydia infection is initiated with the expression of a chlamydial early gene product(s), which isolate the inclusion from the endocytic-lysosomal pathway and makes it fusogenic with sphingomyelin-containing exocytic vesicles
  • This change in vesicular interaction allows the delivery of the vacuole to the peri-Golgi region of the host cell
  • Antigens from all members of the Chlamydia genus display heat resistance and sensitivity to oxidation by sodium periodate
  • Clone L21-10 specifically detects major outer membrane protein (MOMP) from Chlamydia genus
  • It displays strong reactivity with Chlamydial serovars D and L3 and weak reactivity with Ba, E, G, L1, and L2
  • MOMP, a cysteine-rich molecule, plays a vital role in maintaining the structural and functional properties of the chlamydial outer membrane
  • It contains determinants that confer type, subspecies, and species antigenic properties to the protein
  • (Ref.: Zhang, YX et al., (1987)
  • J
  • Immunol
  • 138(2); 575-581).

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Show Difference

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Fischer Scientific

MABF216625

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Antigen:
Chlamydial MOMP

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
N/A

Immunogen:
Formalin killed Chlamydia trachomatis (L2/LGV-434).

Quantity:
25 μg

Research Discipline:
Inflammation & Immunology

Test Specificity:
Clone L21-10 specifically detects outer membrane protein from Chlamydia genus. It displays strong reactivity with serovars D and L3 and weak reactivity with Ba, E, G, L1, and L2.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2a λ

Applications:
Dot Blot, Immunofluorescence, Immunoprecipitation, Western Blot

Clone:
L21-10

Dilution:
Immunoprecipitation Analysis: A representative lot immunoprecipiated Chlamydial MOMP in Immunoprecipitation applications (Zhang, Y.X., et. al. (1987). J Immunol. 138(2):575-81).Immunofluorescence Analysis: A representative lot detected Chlamydial MOMP in Immunofluorescence applications (Weber, M.M., et. al. (2017). Cell Rep. 19(7):1406-1417; Zhang, Y.X., et. al. (1987). J Immunol. 138(2):575-81).Western Blotting Analysis: A representative lot detected Chlamydial MOMP in Western Blotting applications (Baehr, W., et. al. (1988). Proc Natl Acad Sci USA. 85(11):4000-4; Zhang, Y.X., et. al. (1987). J Immunol. 138(2):575-81).Dot Blot Analysis: A representative lot detected Chlamydial MOMP in Dot Blot applications (Zhang, Y.X., et. al. (1987). J Immunol. 138(2):575-81).

Gene Alias:
Chlamydia major membrane protein

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Bacteria

Form:
Purified

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MABF216MI

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Antigen:
Microsialin/CD68

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Cd68

Immunogen:
Recombinant protein corresponding to mouse Microsialin/CD68.

Quantity:
100 μg

Research Discipline:
__

Test Specificity:
__

Content And Storage:
2-8°C for one year

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
9

Dilution:
__

Gene Alias:
__

Host Species:
Rat

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

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MABF21811MI

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Antigen:
CXCR3 (CD183)

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
Cxcr3, Cmkar3

Immunogen:
A multiple antigen peptide (MAPS8) corresponding to 37 amino acids from the N-terminal region of murine C-X-C chemokine receptor 3 (CXCR3).

Quantity:
100 μL

Research Discipline:
Inflammation and Immunology

Test Specificity:
Clone 173 is an Armenian Hamster monoclonal antibody that specifically detects CXCR3 on cells from wild-type, but not from CXCR3-/- mice.

Content And Storage:
Stable for 1 year at -20°C from date of receipt.

Isotype:
IgG

Applications:
Flow Cytometry, Inhibition Assays, Radioimmune Assays (RIA)

Clone:
173

Dilution:
__

Gene Alias:
C-X-C chemokine receptor type 3;CXC-R3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183

Host Species:
Armenian Hamster

Purification Method:
Protein G Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

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MABF21812MI

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Antigen:
CXCR3 (CD183)

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
Cxcr3, Cmkar3

Immunogen:
A multiple antigen peptide (MAPS8) corresponding to 37 amino acids from the N-terminal region of murine C-X-C chemokine receptor 3 (CXCR3).

Quantity:
25 μL

Research Discipline:
Inflammation and Immunology

Test Specificity:
Clone 173 is an Armenian Hamster monoclonal antibody that specifically detects CXCR3 on cells from wild-type, but not from CXCR3-/- mice.

Content And Storage:
Stable for 1 year at -20°C from date of receipt.

Isotype:
IgG

Applications:
Flow Cytometry, Inhibition Assays, Radioimmune Assays (RIA)

Clone:
173

Dilution:
__

Gene Alias:
C-X-C chemokine receptor type 3;CXC-R3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183

Host Species:
Armenian Hamster

Purification Method:
Protein G Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified