MABN2185MI

MilliporeSigma™ LGMN, Mouse, Unlabeled, Clone: 6A7.2,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABN2185MI-Each-of-1 In Stock ₹ 37,817.52

MABN2185MI - Each of 1

₹ 37,817.52

In Stock

Quantity

1

Base Price: ₹ 37,817.52

GST (18%): ₹ 6,807.154

Total Price: ₹ 44,624.674

Antigen

LGMN

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse monoclonal antibody IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q99538

Immunogen

GST-tagged recombinant fragment corresponding to 95 amino acids from the internal region of human LGMN.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_001008530

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

6A7.2

Conjugate

Unconjugated

Gene

LGMN, PRCS1

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 6A7.2 of detects LGMN in multiple human tissues by Western blotting and immunohistochemistry.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG2a κ

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Description

  • Legumain (UniProt: Q99538; EC:3.4.22.34, also known as Asparaginyl endopeptidase; Protease, cysteine 1) is encoded by LGMN (also known as PRSC1) gene (Gene ID 5641) in human
  • Legumain is a lysosomal enzyme with strict specificity of the hydrolysis of asparaginyl bonds
  • It is shown to be ubiquitously distributed with abundance in kidney, heart, and placenta
  • In the zymogen form, the uncleaved propeptide blocks access to the active site
  • It is activated autocatlytically by acidic pH and the active form is shown to be monomeric
  • Legumain plays a pivotal role in the endosomal/lysosomal degradation system and is involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation
  • Legumain deficiency causes the accumulation of pro-cathepsins B, H and L
  • Overexpression of legumain is associated with invasion and metastasis in a majority of solid tumors.

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MilliporeSigma™

MABN2185MI

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Antigen:
LGMN

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q99538

Immunogen:
GST-tagged recombinant fragment corresponding to 95 amino acids from the internal region of human LGMN.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_001008530

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
6A7.2

Conjugate:
Unconjugated

Gene:
LGMN, PRCS1

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 6A7.2 of detects LGMN in multiple human tissues by Western blotting and immunohistochemistry.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ

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MABN2186MI

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Antigen:
DPP6

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
GST-tagged recombinant fragement corresponding to 72 amino acids from the N-terminal half of human DPP6.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_570629

Target Species:
Mouse, Human, Rat

Form:
Purified

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
7G1.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 7G1.1 detected DPP6 in mouse brain.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Img

Fischer Scientific

MABN2249-100

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Antigen:
CHRNA2

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
GST/His-tagged recombinant fragment corresponding to 52 amino acids from the N-terminal region of human Neuronal acetylcholine receptor subunit alpha-2 (CHRNA2).

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000733

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Clone:
5B2.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 5B2.1 detects human Neuronal acetylcholine receptor subunit alpha-2 (CHRNA2). It targets an epitope within 52 amino acids from the N-terminal region extracellular domain.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Img

Fischer Scientific

MABN2249-25

--


Antigen:
CHRNA2

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
GST/His-tagged recombinant fragment corresponding to 52 amino acids from the N-terminal region of human Neuronal acetylcholine receptor subunit alpha-2 (CHRNA2).

Quantity:
25 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000733

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Clone:
5B2.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 5B2.1 detects human Neuronal acetylcholine receptor subunit alpha-2 (CHRNA2). It targets an epitope within 52 amino acids from the N-terminal region extracellular domain.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ