MABS204625
ApoB, Mouse anti-Mouse, Rat, Hamster, Clone: 2G11, Millipore Sigma™
Manufacturer: MilliporeSigma
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS204625-Each-of-1 | In Stock | ₹ 16,456.61 |
MABS204625 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
ApoB
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
Apob
Immunogen
ApoB-containing lipoproteins isolated from Apoe -/- Apob 48/48 mice.
Quantity
25 μg
Research Discipline
Signaling
Test Specificity
Clone 2G11 detects Apolipoprotein B in Mouse, Rat, and Hamster plasma and tissues. It binds to ApoB-48 and ApoB-100, but not to ApoB-39.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Isotype
IgG1 κ
Applications
ELISA, Western Blot
Clone
2G11
Dilution
Western Blotting Analysis: 4 μg/mL from a representative lot detected ApoB in 10μg of rat liver and mouse liver tissue lysate. Western Blotting Analysis: A representative lot detected ApoB in Western Blotting applications (Nguyen, A.T., et. al. (2006). Biochem Biophys Acta. 1761(2):182-5; Cheng, D., et. al. (2016). J Biol Chem. 291(45):23793-23803). ELISA Analysis: A representative lot detected ApoB in ELISA applications (Nguyen, A.T., et. al. (2006). Biochem Biophys Acta. 1761(2):182-5).
Gene Alias
Apolipoprotein B-100
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Mouse, Rat, Hamster
Form
Purified
Description
- Detects Apolipoprotein B using this mouse monoclonal Anti-ApoB, clone 2G11 , Cat
- No
- MABS2046, is a mouse monoclonal antibody that detects Apolipoprotein B in Mouse, Rat, and Hamster and is tested for use in ELISA and Western Blotting
- Apolipoprotein B-100 (UniProt: E9Q414; also known as Apo B-100) is encoded by the Apob gene (Gene ID: 238055) in murine species
- Apolipoprotein B is a major protein constituent of chylomicrons
- Apo B particles are made up of lipids and proteins and each Apo B is bordered by a phospholipid monolayer with an inner core composed of variable amounts of triglycerides and cholesterol esters
- Apo B is synthesized with a signal peptide (aa 1-27) that is subsequently cleaved off
- Two isoforms of Apo B are produced- Apo B-100 is synthesized in the liver and Apo B-48 is produced in the intestine
- Apo B-100 contains the region that binds to the LDL receptor
- It contains VLDL particles, VLDL remnant particles and LDL particles
- On the other hand, the Apo B-48 particles are made of chylomicrons and chylomicron remnant particles
- Generally, LDL particles account for approximately 90% of Apo B particles in plasma
- Abnormal trapping of an Apo B is a major factor in the development of atherosclerotic lesions
- When Apo B particles degrade cholesterol is retained with macrophages that induce inflammatory response
- Further entry and entrapment of Apo B can promote cardiovascular pathology over time
- (Ref.: Sniderman, A et al
- (2010)
- Nat
- Rev
- Endocrinol
- 6(6); 335-346).
Compare Similar Items
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Antigen: ApoB
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: Apob
Immunogen: ApoB-containing lipoproteins isolated from Apoe -/- Apob 48/48 mice.
Quantity: 25 μg
Research Discipline: Signaling
Test Specificity: Clone 2G11 detects Apolipoprotein B in Mouse, Rat, and Hamster plasma and tissues. It binds to ApoB-48 and ApoB-100, but not to ApoB-39.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Applications: ELISA, Western Blot
Clone: 2G11
Dilution: Western Blotting Analysis: 4 μg/mL from a representative lot detected ApoB in 10μg of rat liver and mouse liver tissue lysate. Western Blotting Analysis: A representative lot detected ApoB in Western Blotting applications (Nguyen, A.T., et. al. (2006). Biochem Biophys Acta. 1761(2):182-5; Cheng, D., et. al. (2016). J Biol Chem. 291(45):23793-23803). ELISA Analysis: A representative lot detected ApoB in ELISA applications (Nguyen, A.T., et. al. (2006). Biochem Biophys Acta. 1761(2):182-5).
Gene Alias: Apolipoprotein B-100
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Rat, Hamster
Form: Purified
Antigen:
ApoB
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
Apob
Immunogen:
ApoB-containing lipoproteins isolated from Apoe -/- Apob 48/48 mice.
Quantity:
25 μg
Research Discipline:
Signaling
Test Specificity:
Clone 2G11 detects Apolipoprotein B in Mouse, Rat, and Hamster plasma and tissues. It binds to ApoB-48 and ApoB-100, but not to ApoB-39.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
ELISA, Western Blot
Clone:
2G11
Dilution:
Western Blotting Analysis: 4 μg/mL from a representative lot detected ApoB in 10μg of rat liver and mouse liver tissue lysate. Western Blotting Analysis: A representative lot detected ApoB in Western Blotting applications (Nguyen, A.T., et. al. (2006). Biochem Biophys Acta. 1761(2):182-5; Cheng, D., et. al. (2016). J Biol Chem. 291(45):23793-23803). ELISA Analysis: A representative lot detected ApoB in ELISA applications (Nguyen, A.T., et. al. (2006). Biochem Biophys Acta. 1761(2):182-5).
Gene Alias:
Apolipoprotein B-100
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Rat, Hamster
Form:
Purified
Antigen: MT-ND2
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal antibody IgG2a in buffer containing HEPES-Buffered Saline (150 mM NaCl, 15 mM HEPES, pH 7.2) with 0.02% sodium azide.
Gene Symbols: MT-ND2;MTND2;NADH2;ND2
Immunogen: Synthetic peptide corresponding to the N-terminus of human MT-ND2.
Quantity: 25 μg
Research Discipline: Signaling
Test Specificity: Clone 9E12-1B3 detects NADH-ubiquinone oxidoreductase chain 2 (MT-ND2) in mitochondria from human cells. It targets an epitope within the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2a κ
Applications: Western Blot
Clone: 9E12-1B3
Dilution: Western Blotting Analysis: 2μg/mL from a representative lot detected MT-ND2 in mitochondria from human neonatal dermal fibroblasts and mitochondria from human neonatal dermal fibroblasts depleted of mtDNA (Courtesy of Michael F. Marusich, Ph.D., mAbDx, Inc., Eugene, OR USA).
Gene Alias: NADH-ubiquinone oxidoreductase chain 2;EC: 1.6.5.3;NADH dehydrogenase subunit 2;MT-ND2
Host Species: Mouse
Purification Method: Protein L
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
MT-ND2
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing HEPES-Buffered Saline (150 mM NaCl, 15 mM HEPES, pH 7.2) with 0.02% sodium azide.
Gene Symbols:
MT-ND2;MTND2;NADH2;ND2
Immunogen:
Synthetic peptide corresponding to the N-terminus of human MT-ND2.
Quantity:
25 μg
Research Discipline:
Signaling
Test Specificity:
Clone 9E12-1B3 detects NADH-ubiquinone oxidoreductase chain 2 (MT-ND2) in mitochondria from human cells. It targets an epitope within the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Western Blot
Clone:
9E12-1B3
Dilution:
Western Blotting Analysis: 2μg/mL from a representative lot detected MT-ND2 in mitochondria from human neonatal dermal fibroblasts and mitochondria from human neonatal dermal fibroblasts depleted of mtDNA (Courtesy of Michael F. Marusich, Ph.D., mAbDx, Inc., Eugene, OR USA).
Gene Alias:
NADH-ubiquinone oxidoreductase chain 2;EC: 1.6.5.3;NADH dehydrogenase subunit 2;MT-ND2
Host Species:
Mouse
Purification Method:
Protein L
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: Adenylate Cyclase 5
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: Adcy5
Immunogen: KLH-conjugated linear peptide corresponding to 20 amino acids from the cytoplasmic domain of murine adenylate cyclase V.
Quantity: 25 μg
Research Discipline: Signaling
Test Specificity: Clone 19D5.C1 detects Adnylate Cyclase 5 in murine, rat, and procine cells. It targets an epitope within 20 amino acids from the cytoplasmic domain.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Applications: ELISA, Western Blot
Clone: 19D5.C1
Dilution: __
Gene Alias: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Porcine, Rat
Form: Purified
Antigen:
Adenylate Cyclase 5
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
Adcy5
Immunogen:
KLH-conjugated linear peptide corresponding to 20 amino acids from the cytoplasmic domain of murine adenylate cyclase V.
Quantity:
25 μg
Research Discipline:
Signaling
Test Specificity:
Clone 19D5.C1 detects Adnylate Cyclase 5 in murine, rat, and procine cells. It targets an epitope within 20 amino acids from the cytoplasmic domain.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
ELISA, Western Blot
Clone:
19D5.C1
Dilution:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Porcine, Rat
Form:
Purified
Antigen: TFF3
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: TFF3, ITF, TFI
Immunogen: Recombinant human dimeric TFF3.
Quantity: 100 μg
Research Discipline: Signaling
Test Specificity: Clone TFF-286 is a mouse monoclonal antibody that detects human Trefoil factor 3 (TFF3).
Content And Storage: Stable for 1 year at 2 to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: ELISA, Western Blot
Clone: TFF-286
Dilution: __
Gene Alias: Trefoil factor 3;Intestinal trefoil factor;hITF;Polypeptide P1.B;hP1.B
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
TFF3
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
TFF3, ITF, TFI
Immunogen:
Recombinant human dimeric TFF3.
Quantity:
100 μg
Research Discipline:
Signaling
Test Specificity:
Clone TFF-286 is a mouse monoclonal antibody that detects human Trefoil factor 3 (TFF3).
Content And Storage:
Stable for 1 year at 2 to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
ELISA, Western Blot
Clone:
TFF-286
Dilution:
__
Gene Alias:
Trefoil factor 3;Intestinal trefoil factor;hITF;Polypeptide P1.B;hP1.B
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified