MABS529MI

MilliporeSigma™ Rat anti-MEKK5, Clone: TC003,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS529MI-Each-of-1 In Stock ₹ 38,734.72

MABS529MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

MEKK5

Classification

Monoclonal

Formulation

Purified rat monoclonal IgG2bκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

Map3k5; Ask1; Mekk5

Immunogen

Recombinant protein corresponding to the C-terminus of mouse MEKK5.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_032606

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2b κ

Applications

Western Blot

Clone

TC003

Gene Accession No.

O35099

Host Species

Rat

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Mouse

Form

Purified

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Description

  • Specifically detects MEKK5 clone: TC003 in Mouse samples, and it is validated for Western Blotting MEKK5 (MAP3K5) is a key kinase for our innate immunity and for mediating cellular signaling cascades evoked by changes in the external cellular environment
  • As such, MEKK5 is critical for cell fate during development, apoptosis, and cell survival as well as in modulating the host defense responses from a wide range of pathogens
  • MEKK5 acts as an upstream activator of the MKK/JNK signaling pathways and the p38 MAPK signaling pathways that ultimately results in activating multiple kinases such as MAP2K3/Mkk3 or MKK6/MMK7
  • MEKK5 is inactive as an unphosphorylated homodimer, and MEKK5 binds both upstream activators and downstream substrates in multi-molecular complexes
  • Expression is widespread and localized in the cytoplasmic in the perinuclear endoplasmic reticulum region, and MEKK5 is abundantly expressed in heart and pancreas
  • MEKK5 is regulated via phosphorylation and ubiquitination and degradation via the proteasome.

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MilliporeSigma™

MABS529MI

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Antigen:
MEKK5

Classification:
Monoclonal

Formulation:
Purified rat monoclonal IgG2bκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Map3k5; Ask1; Mekk5

Immunogen:
Recombinant protein corresponding to the C-terminus of mouse MEKK5.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_032606

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
Western Blot

Clone:
TC003

Gene Accession No.:
O35099

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

Img

MilliporeSigma

MABS62MI

--


Antigen:
GREB1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
GREB1

Immunogen:
Recombinant protein corresponding to human GREB1.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C for one year

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
GREB1Ab

Gene Accession No.:
NP_055483

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

MABS64MI

--


Antigen:
phospho-p38 (Thr180/Tyr182)

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgGκ in buffer containing 0.1MTris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide.

Gene Symbols:
SAPK2a, MAPK14, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, p38ALPHA, RK, Mxi2, EXIP

Immunogen:
Linear peptide corresponding to human p38 phosphorylated at Thr180 and Tyr182.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C for one year

Isotype:
__

Applications:
Immunocytochemistry, Western Blot

Clone:
6E5.2

Gene Accession No.:
NP_001306.1

Host Species:
Mouse

Purification Method:
Protein G purfied

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified

Img

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MABS65MI

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Antigen:
Insulin Receptor

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide.

Gene Symbols:
IMSR, CD220, HHF5, IR

Immunogen:
Recombinant protein corresponding to the C-terminus of human Insulin Receptor, beta subunit.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C for one year

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Western Blot

Clone:
CT-3

Gene Accession No.:
NP_000199.2

Host Species:
Mouse

Purification Method:
Protein G purfied

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified