MABS508MI
MilliporeSigma™ Mouse anti-GOT1, Clone: 1F5.2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS508MI-Each-of-1 | In Stock | ₹ 37,453.03 |
MABS508MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,453.03
GST (18%): ₹ 6,741.545
Total Price: ₹ 44,194.575
Antigen
GOT1
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
GOT1
Immunogen
GST-tagged Recombinant protein corresponding to the N-terminal region of human GOT1.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_002070
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2b κ
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
1F5.2
Gene Accession No.
P17174
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects GOT1 clone: 1F5.2 in Human samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting Aspartate aminotransferase, cytoplasmic (EC 2.6.2.1.; EC 2.6.2.3; UniProt P17174; also known as Aspartate aminotransferase 1, Aspartate transaminase 1, cAspAT, cCAT, Cysteine aminotransferase cytoplasmic, Cysteine transaminase cytoplasmic, Glutamate oxaloacetate transaminase 1, Growth-inhibiting protein 18, Transaminase A) is encoded by the GOT1 (also known as GIG18, ASTQTL1) gene (Gene ID 2805) in human
- Aspartate aminotransferase is expressed in many types of cells and tissues and is conserved among prokaryotic and eukaryotic organisms
- There exist two highly similar AST forms in mammals, the cytosolic cAST (encoded by the GOT1 gene) and the mitochondrial mAST (encoded by the GOT2 gene)
- Serum aspartate aminotransferase activity is largely that of cAST/GOT1, and elevated serum AST activity is associated with liver, heart, and muscle injury
- AST catalyzes the reversible conversion between aspartate/alpha-ketoglutarate and oxaloacetate/glutamate, increasing oxaloacetate concentration therefore shifts the equilibrium of AST-catalzed reaction toward aspartate/alpha-ketoglutarate and away from glutatmate
- Lowering blood glutamate concentration via oxaloacetate i.v
- injection prompts an efflux of excess extracellular brain glutamate into the blood, which is reported to allevate the infarct size and edema in a rat model of ischemia induced by transient occlusion of the middle cerebral artery occlusion (MCAO).
Compare Similar Items
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Antigen: GOT1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: GOT1
Immunogen: GST-tagged Recombinant protein corresponding to the N-terminal region of human GOT1.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_002070
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 1F5.2
Gene Accession No.: P17174
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
GOT1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
GOT1
Immunogen:
GST-tagged Recombinant protein corresponding to the N-terminal region of human GOT1.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_002070
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
1F5.2
Gene Accession No.:
P17174
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: CYP7B1
Classification: Monoclonal
Formulation: __
Gene Symbols: CYP7B1
Immunogen: Ovalbumin-conjugated linear peptide corresponding to 9 amino acids from the C-terminal end of human 25-hydroxycholesterol 7-alpha-hydroxylase (CYP7B1).
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_004811
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 λ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: M17P3F2
Gene Accession No.: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
CYP7B1
Classification:
Monoclonal
Formulation:
__
Gene Symbols:
CYP7B1
Immunogen:
Ovalbumin-conjugated linear peptide corresponding to 9 amino acids from the C-terminal end of human 25-hydroxycholesterol 7-alpha-hydroxylase (CYP7B1).
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_004811
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 λ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
M17P3F2
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: __
Classification: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: __
Isotype: __
Applications: __
Clone: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
__
Isotype:
__
Applications:
__
Clone:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Target Species:
__
Form:
__
Antigen: CBS
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CBS
Immunogen: Recombinant protein corresponding to the N-terminal of human CBS.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001171479
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 9F3.2
Gene Accession No.: P35520
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
CBS
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CBS
Immunogen:
Recombinant protein corresponding to the N-terminal of human CBS.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001171479
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
9F3.2
Gene Accession No.:
P35520
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified