MABN814MI
MilliporeSigma™ Mouse anti-Twinkle, Clone: 13A10.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN814MI-Each-of-1 | In Stock | ₹ 37,453.03 |
MABN814MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,453.03
GST (18%): ₹ 6,741.545
Total Price: ₹ 44,194.575
Antigen
Twinkle
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
EPO1; C10orf2
Immunogen
GST-tagged recombinant protein corresponding to the C-terminal of human Twinkle.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_068602
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2a κ
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
13A10.1
Gene Accession No.
Q96RR1
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects Twinkle clone: 13A10.1 in Human samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting Twinkle protein, mitochondrial (EC 3.6.4.12; UniProt Q96RR1; also known as Ataxin 8, Mitochondrial twinkle protein, Progressive external ophthalmoplegia 1 protein, T7 gp4-like protein with intramitochondrial nucleoid localization, T7 helicase-related protein with intramitochondrial nucleoid localization, T7-like mitochondrial DNA helicase) is encoded by the EPO1 (also known as ATXN8, C10orf2, IOSCA, MTDPS7, PEO, PEO1, PEOA3, PRLTS5, SANDO, SCA8, TWINL) gene (Gene ID 56662) in human
- Mitochondrial DNA (mtDNA) replication involves the catalytic and accessory subunits of DNA polymerase gamma, the mtDNA helicase Twinkle, the mitochondrial single-stranded DNA-binding protein, and the mitochondrial RNA polymerase
- Cells expressing Twinkle mutants accumulate double-stranded mtDNA replication intermediates with loss of RNA associated with the lagging strand, consistent with the role of Twinkle in unwinding double-stranded mtDNA
- Mutations in the human Twinkle gene (C10orf2) cause autosomal dominant progressive external ophthalmoplegia (PEO), associated with multiple mtDNA deletions.
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Antigen: Twinkle
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: EPO1; C10orf2
Immunogen: GST-tagged recombinant protein corresponding to the C-terminal of human Twinkle.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_068602
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 13A10.1
Gene Accession No.: Q96RR1
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Twinkle
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
EPO1; C10orf2
Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal of human Twinkle.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_068602
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
13A10.1
Gene Accession No.:
Q96RR1
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: Ninjurin-1/NINJ1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: NINJ1; NIN1; NINJURIN
Immunogen: GST-tagged recombinant human Ninjurin-1/NINJ1 N-terminal extracellular domain.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_004139
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 12H6.1
Gene Accession No.: Q92982
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Ninjurin-1/NINJ1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
NINJ1; NIN1; NINJURIN
Immunogen:
GST-tagged recombinant human Ninjurin-1/NINJ1 N-terminal extracellular domain.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_004139
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
12H6.1
Gene Accession No.:
Q92982
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: Tau, oligomeric
Classification: Monoclonal
Formulation: Purified mouse IgG2aκ in buffer containing PBS without preservatives.
Gene Symbols: __
Immunogen: Recombinant human Tau-441 (Tau-F, Tau-4, 2N4R isoform) oligomers (Lasagna-Reeves, C. A., et al. (2012). FASEB J. 26(5):1946-1959).
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_058519.3
Content And Storage: Stable for 1 year at -20°C from date of receipt.
Isotype: IgG2a κ
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Neutralization, Western Blot
Clone: TOMA-1
Gene Accession No.: P10636
Host Species: Mouse
Purification Method: Protein A Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Tau, oligomeric
Classification:
Monoclonal
Formulation:
Purified mouse IgG2aκ in buffer containing PBS without preservatives.
Gene Symbols:
__
Immunogen:
Recombinant human Tau-441 (Tau-F, Tau-4, 2N4R isoform) oligomers (Lasagna-Reeves, C. A., et al. (2012). FASEB J. 26(5):1946-1959).
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_058519.3
Content And Storage:
Stable for 1 year at -20°C from date of receipt.
Isotype:
IgG2a κ
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Neutralization, Western Blot
Clone:
TOMA-1
Gene Accession No.:
P10636
Host Species:
Mouse
Purification Method:
Protein A Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: polyQ Disease Proteins
Classification: Monoclonal
Formulation: Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: N-terminally GST-tagged human Huntingtin (Htt) fragment corresponding to exon 1-coded seqeunce containing a stretch of 66 glutamines (GST-171-Q66; Miller, J., et al. (2011). Nat. Chem. Biol. 7(12):925-934).
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): __
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry, Inhibition Assays, Western Blot
Clone: 3B5H10
Gene Accession No.: P42858
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
polyQ Disease Proteins
Classification:
Monoclonal
Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
N-terminally GST-tagged human Huntingtin (Htt) fragment corresponding to exon 1-coded seqeunce containing a stretch of 66 glutamines (GST-171-Q66; Miller, J., et al. (2011). Nat. Chem. Biol. 7(12):925-934).
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
__
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry, Inhibition Assays, Western Blot
Clone:
3B5H10
Gene Accession No.:
P42858
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified