MABT419MI

MilliporeSigma™ Mouse anti-CD2AP, Clone: 2A2.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABT419MI-Each-of-1 In Stock ₹ 41,307.51

MABT419MI - Each of 1

₹ 41,307.51

In Stock

Quantity

1

Base Price: ₹ 41,307.51

GST (18%): ₹ 7,435.352

Total Price: ₹ 48,742.862

Antigen

CD2AP

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

CD2AP

Immunogen

GST-tagged recombinant protein corresponding to the C-terminal half of human CD2AP.

Quantity

100 μg

Research Discipline

Cell Structure

Gene ID (Entrez)

NP_036252

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG1 κ

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

2A2.1

Gene Accession No.

Q9Y5K6

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects CD2AP clone: 2A2.1 in Human samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting CD2-associated protein (UniProt Q9Y5K6; also known as Adapter protein CMS, Cas ligand with multiple SH3 domains) is encoded by the CD2AP (also known as CMS) gene (Gene ID 23607) in human
  • CD2AP is an adapter protein expressed in all tissues except brain
  • CD2AP harbors three SH3 domains at its N-terminal, a proline-rich domain, and a C-terminal leucine-zipper domain that mediates CD2AP homodimerization
  • CD2AP is known to interact with actin-associated proteins, such as cortactin, and actin capping protein CAPZ
  • The SH3 domains of CD2AP mediate its association to the hypervariable C terminal region of Rac1, allowing CD2AP to act as a linker between Rac1 and the actin-binding proteins cortactin and CAPZ
  • CD2AP also plays an important role in the formation of the slit diaphragm in the kidney glomerulus between podocyte foot processes by linking the cell-cell adhesion protein nephrin to the cytoskeleton
  • CD2AP gene mutations are associated with kidney diseases such as sporadic nephrotic syndrome and focal segmental glomerulosclerosis.

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MilliporeSigma™

MABT419MI

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Antigen:
CD2AP

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
CD2AP

Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal half of human CD2AP.

Quantity:
100 μg

Research Discipline:
Cell Structure

Gene ID (Entrez):
NP_036252

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
2A2.1

Gene Accession No.:
Q9Y5K6

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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Sigma Aldrich

MABT42

clone M18/2, from rat...


Antigen:
__

Classification:
__

Formulation:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
__

Isotype:
__

Applications:
__

Clone:
__

Gene Accession No.:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Target Species:
__

Form:
__

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MABT457MI

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Antigen:
ALPP

Classification:
Monoclonal

Formulation:
Mouse monoclonal IgG2b ascitic fluid containing up to 0.1% sodium azide.

Gene Symbols:
ALP, PALP, PLAP, FLJ61142, ALPP

Immunogen:
Purified recombinant fragment of human ALPP expressed in E. Coli.

Quantity:
100 μL

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Isotype:
IgG2b

Applications:
Immunohistochemistry, Western Blot

Clone:
3E5

Gene Accession No.:
__

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Ascites

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Antigen:
IL-34

Classification:
Monoclonal

Formulation:
Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.

Gene Symbols:
IL34

Immunogen:
Purified recombinant fragment of human IL-34 expressed in E. Coli

Quantity:
100 μL

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Isotype:
IgG1

Applications:
Flow Cytometry, Immunofluorescence

Clone:
1D12

Gene Accession No.:
__

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Ascites