MABN842MI

MilliporeSigma™ Mouse anti-PERK, Clone: 4F6.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABN842MI-Each-of-1 In Stock ₹ 39,063.27

MABN842MI - Each of 1

₹ 39,063.27

In Stock

Quantity

1

Base Price: ₹ 39,063.27

GST (18%): ₹ 7,031.389

Total Price: ₹ 46,094.659

Antigen

PERK

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

EIF2AK3; PEK; PERK

Immunogen

GST-tagged recombinant protein corresponding to the Internal (C-terminal half) of human PERK.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_004827

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2b κ

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

4F6.1

Gene Accession No.

Q9NZJ5

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Related Products

Img

MilliporeSigma™

MABN814MI

--

Img

MilliporeSigma™

MABN361MI

--

Img

MilliporeSigma™

MABC603MI

--

Img

MilliporeSigma™

MABS508MI

--

Img

MilliporeSigma™

MABT419MI

--

Img

MilliporeSigma™

MABN804MI

--

Img

MilliporeSigma™

MABS518MI

--

Img

MilliporeSigma™

MABC974MI

--

Description

  • Specifically detects PERK clone: 4F6.1 in Human samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1; UniProt Q9NZJ5; also known as Eukaryotic translation initiation factor 2 alpha kinase 3, HsPEK, Pancreatic EIF2-alpha kinase, PRKR-like endoplasmic reticulum kinase) is encoded by the EIF2AK3 (also known as PEK, PERK, WRS) gene (Gene ID 9451) in human
  • The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) induces the activation of three main unfold protein response (UPR) pathways, the inositol requiring enzyme-1 (IRE1) pathway, the activating transcription factor 6 (ATF6) pathway, and the protein kinase-like ER kinase (PERK) pathway
  • The PERK pathway involves PERK auto-phosphorylation/activation, resulting in PERK phosphorylation of eIF2α, which in turn leads to increased ATF4 transcription and ATF4-mediated CAAT/enhancer binding protein (C/EBP) homologous protein (CHOP) upregulation.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

MABN842MI

--


Antigen:
PERK

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
EIF2AK3; PEK; PERK

Immunogen:
GST-tagged recombinant protein corresponding to the Internal (C-terminal half) of human PERK.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_004827

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
4F6.1

Gene Accession No.:
Q9NZJ5

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

MABN844MI

--


Antigen:
Neurophysin 1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Oxt; Ot

Immunogen:
KLH-conjugated acid soluble extract of rat (Sprague-Dawley) intermediate lobes corresponding to rat Neurophysin 1.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_037128

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
Western Blot

Clone:
PS 38

Gene Accession No.:
P01179

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Rat

Form:
Purified

Img

MilliporeSigma™

MABN845MI

--


Antigen:
Neurophysin 2/NP-AVP

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Avp

Immunogen:
KLH-conjugated acid soluble extract of rat (Sprague-Dawley) intermediate lobes.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_058688

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG2b κ

Applications:
Immunoassay, ELISA, Immunohistochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot

Clone:
PS 41

Gene Accession No.:
P01186

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Rat

Form:
Purified

Img

MilliporeSigma™

MABN851MI

--


Antigen:
CRALBP

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
RLBP1, CRALBP

Immunogen:
GST-tagged recombinant protein corresponding to the N-terminal half of human CRALBP.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000317

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
3H9.1

Gene Accession No.:
P12271

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified