MABN851MI

MilliporeSigma™ anti-CRALBP Clone: 3H9.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABN851MI-Each-of-1 In Stock ₹ 38,734.72

MABN851MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

CRALBP

Classification

Monoclonal

Conjugate

Unconjugated

Gene Accession No.

P12271

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Mouse

Form

Purified

Applications

Western Blot

Clone

3H9.1

Formulation

Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

RLBP1, CRALBP

Immunogen

GST-tagged recombinant protein corresponding to the N-terminal half of human CRALBP.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_000317

Content And Storage

2°C to 8°C for one year from date of shipment

Isotype

IgG1 κ

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Description

  • Specifically detects CRALBP Clone: 3H9.1 in Mouse samples, and it is validated for Western Blotting Retinaldehyde-binding protein 1 (UniProt P12271; also known as Cellular retinaldehyde-binding protein) is encoded by the RLBP1 (also known as CRALBP) gene (Gene ID 6017) in human
  • CRALBP is a retinoid-binding protein expressed in retinal pigment epithelial (RPE) cells and Müller glia involved in the retinal visual cycle
  • Photoactivation of a visual pigment molecule in vertebrate rod and cone photoreceptors renders the pigment molecule into a bleached all-trans retinal form, which must be exported out of the photoreceptors to be converted back to the light-sensitive 11-cis retinal form in RPE cells (for both rods and cones) or in retinal Müller glia (for cones only)
  • The 11-cis chromophore is then imported back into photoreceptors, where it combines with a free opsin to regenerate the visual pigment
  • CRALBP is a 36kDa water-soluble protein that facilitates the intracellular transport of hydrophobic 11-cis retinoids
  • Mutations in human RLBP1 cause several autosomal recessive retinal diseases, such as retinitis pigmentosa, Bothnia dystrophy, retinitis punctata albescens, fundus albipunctatus, and Newfoundland rod-cone dystrophy
  • Likewise, Rlbp1-knockout mice exhibit M-opsin mislocalization, M-cone loss, and impaired cone-driven visual behavior and light responses
  • Viral expression of CRALBP in Müller cells, but not RPE cells, is reported to rescue the retinal visual cycle and M-cone sensitivity in Rlbp1-knockout mice.

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MilliporeSigma™

MABN851MI

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Antigen:
CRALBP

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
P12271

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

Applications:
Western Blot

Clone:
3H9.1

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
RLBP1, CRALBP

Immunogen:
GST-tagged recombinant protein corresponding to the N-terminal half of human CRALBP.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000317

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG1 κ

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MABN852-100

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Antigen:
APP

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse, Human

Form:
Purified

Applications:
ELISA, Immunocytochemistry, Inhibition Assays, Western Blot

Clone:
2B3

Formulation:
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Gene Symbols:
APP,A4,AD1

Immunogen:
A linear peptide corresponding to 15 amino acids from the C-terminal region of human Amyloid-beta A4 protein.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000475

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Isotype:
IgG1 κ

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MABN852-25UG

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Antigen:
APP

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
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Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse, Human

Form:
Purified

Applications:
ELISA, Immunocytochemistry, Inhibition Assays, Western Blot

Clone:
2B3

Formulation:
__

Gene Symbols:
APP,A4,AD1

Immunogen:
A linear peptide corresponding to 15 amino acids from the C-terminal region of human Amyloid-beta A4 protein.

Quantity:
25 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000475

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Isotype:
IgG1 κ

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Antigen:
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Classification:
Monoclonal

Conjugate:
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Gene Accession No.:
Q6ZWR6;Q63128

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Rat

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
200A6

Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
Synthetic peptide corresponding to a sequence within the third coiled coil of rat spliced isoform CPG2 or the tenth Spectrin domain of mouse spliced isoform 1 (a.k.a. Enaptin or Nesprin-1 Giant).

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NM_001079686;CAA64740

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ