MABN866MI
MilliporeSigma™ Mouse anti-Myocilin (NT), Clone: 7.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN866MI-Each-of-1 | In Stock | ₹ 40,486.99 |
MABN866MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,486.99
GST (18%): ₹ 7,287.658
Total Price: ₹ 47,774.648
Antigen
Myocilin (NT)
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
MYOC; GLC1A; TIGR
Immunogen
Recombinant protein corresponding to the N-terminal fragment (aa 33-214) of human Myocilin.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_000252
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG1 κ
Applications
Immunohistochemistry, Western Blot
Clone
7.1
Gene Accession No.
Q99972
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Purified
Related Products
Description
- Specifically detects Myocilin (NT) clone: 7.1 in Human, Mouse samples, and it is validated for Immunohistochemistry, Western Blotting Myocilin (mutated trabecular meshwork-induced glucocorticoid response protein) is encoded by the MYOC gene (also known as GLC1A, GPOA, JOAG, JOAG1, TIGR) in human (Entrez Gene ID 4653)
- Myocilin is produced as a 504 amino acid glycoprotein containing an N-terminal hydrophobic signal peptide sequence, a coiled-coiled leucine zipper domain, and a C-terminal domain with homology to olfactomedins
- Myocilin is commonly identified as a 53/57kDa doublet by gel electrophoresis, and a 66kDa form of the protein is also reported
- Myocilin is known to undergo intracellular endoproteolytic cleavage between Glu214 and Leu215, resulting in a 20kDa N-terminal and a 35kDa C-terminal fragment
- Myocilin is identified as a Lingo-1 receptor ligand and MYOC gene mutations are linked to 10% of juvenile open-angle glaucoma cases and 3-4% of those with primary open-angle glaucoma (PMID 24732711 24741044, 24837143)
- Clone 7.1 is a mouse monoclonal antibody that recognizes an epitope within the N-terminal fragment (aa33-214) and is demonstrated to be suitable for Western blotting, immuncytochemistry, and immunhistochemistry applications
- This clone is reactive toward both human and murine species
- (PMID 18674535 & 23979599).
Compare Similar Items
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Antigen: Myocilin (NT)
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: MYOC; GLC1A; TIGR
Immunogen: Recombinant protein corresponding to the N-terminal fragment (aa 33-214) of human Myocilin.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_000252
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunohistochemistry, Western Blot
Clone: 7.1
Gene Accession No.: Q99972
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Antigen:
Myocilin (NT)
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
MYOC; GLC1A; TIGR
Immunogen:
Recombinant protein corresponding to the N-terminal fragment (aa 33-214) of human Myocilin.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_000252
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Western Blot
Clone:
7.1
Gene Accession No.:
Q99972
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Antigen: Kallikrein 6/KLK6
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in 0.1M Sodium bicarbonate buffer, pH 8.2 with 0.02% Sodium Azide.
Gene Symbols: __
Immunogen: Recombinant full-length human Kallikrein 6.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_002765.1
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: ELISA, Immunohistochemistry (Paraffin), Inhibition Assays
Clone: E24
Gene Accession No.: Q92876
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Kallikrein 6/KLK6
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in 0.1M Sodium bicarbonate buffer, pH 8.2 with 0.02% Sodium Azide.
Gene Symbols:
__
Immunogen:
Recombinant full-length human Kallikrein 6.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_002765.1
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
ELISA, Immunohistochemistry (Paraffin), Inhibition Assays
Clone:
E24
Gene Accession No.:
Q92876
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: GABAA, γ2 subunit
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: GABRG2
Immunogen: GST-tagged recombinant protein corresponding to the cytoplasmic domain of human GABAA γ2 Subunit.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_944494
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: KC4-8A7
Gene Accession No.: P18507
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Bovine, Human, Mouse, Rat
Form: Purified
Antigen:
GABAA, γ2 subunit
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
GABRG2
Immunogen:
GST-tagged recombinant protein corresponding to the cytoplasmic domain of human GABAA γ2 Subunit.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_944494
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
KC4-8A7
Gene Accession No.:
P18507
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mouse, Rat
Form:
Purified
Antigen: phospho-Amyloid beta (Ser26)
Classification: Monoclonal
Formulation: Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: KLH-conjugated linear peptide corresponding to human amyloid beta peptide target region sequence with phosphorylated Ser26.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_000475
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunofluorescence, Western Blot
Clone: 5H11C10
Gene Accession No.: P05067
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
phospho-Amyloid beta (Ser26)
Classification:
Monoclonal
Formulation:
Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
KLH-conjugated linear peptide corresponding to human amyloid beta peptide target region sequence with phosphorylated Ser26.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_000475
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunofluorescence, Western Blot
Clone:
5H11C10
Gene Accession No.:
P05067
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified