MABN873MI
MilliporeSigma™ Kallikrein 6/KLK6, Mouse, Unlabeled, Clone: E24,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN873MI-Each-of-1 | In Stock | ₹ 40,292.08 |
MABN873MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,292.08
GST (18%): ₹ 7,252.574
Total Price: ₹ 47,544.654
Antigen
Kallikrein 6/KLK6
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG1κ antibody in 0.1M Sodium bicarbonate buffer, pH 8.2 with 0.02% Sodium Azide.
Gene Accession No.
Q92876
Immunogen
Recombinant full-length human Kallikrein 6.
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone E24 reacts with kallikrein-6, but not other kallikrein family members. Reactivity against kallikrein-6 spliced isoforms 2&3 reported by UniProt (Q92876) has not been determined.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Applications
ELISA, Immunohistochemistry (Paraffin), Inhibition Assays
Clone
E24
Conjugate
Unconjugated
Gene
KLK6, PRSS18, PRSS9
Host Species
Mouse
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_002765.1
Target Species
Human
Form
Purified
Related Products
Description
- Kallikrein-6 (UniProt Q92876; also known as hK6, Neurosin, Protease M, Serine protease 18, Serine protease 9, SP59, Zyme) is encoded by the KLK6 (also known as PRSS18, PRSS9) gene (Gene ID 5653) in human
- Kallikrein-6 belongs to the kallikrein subfamily of serine proteases, members of which are involved in diverse physiological functions and many are used clinically as biomarkers for cancers
- Originally identified due to its aberrant expression in mammary and ovarian cancers, kallikrein-6 is expressed in a wide range of tissues, including breast, kidney, and the central nervous system
- Kallikrein-6 is known to cleave components of the extracellular matrix (ECM) and is reported to be involved in multiple cellular processes, including inflammation, receptor activation, and apoptosis
- In addition, deregulated KLK6 expression occurs in neurodegenerative and skin disorders, and is a common event in many types of human cancers
- Consequently, KLK6 represents a promising biomarker of early diagnosis and/or unfavorable prognosis in these human malignancies
- Kallikrein-6 is initially produced as a preproprotein with a signal (aa 1-16) and a propeptide (aa 17-21), cleavage of which releases the mature protein (aa 22-244).
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Antigen: Kallikrein 6/KLK6
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ antibody in 0.1M Sodium bicarbonate buffer, pH 8.2 with 0.02% Sodium Azide.
Gene Accession No.: Q92876
Immunogen: Recombinant full-length human Kallikrein 6.
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone E24 reacts with kallikrein-6, but not other kallikrein family members. Reactivity against kallikrein-6 spliced isoforms 2&3 reported by UniProt (Q92876) has not been determined.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: ELISA, Immunohistochemistry (Paraffin), Inhibition Assays
Clone: E24
Conjugate: Unconjugated
Gene: KLK6, PRSS18, PRSS9
Host Species: Mouse
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_002765.1
Target Species: Human
Form: Purified
Antigen:
Kallikrein 6/KLK6
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ antibody in 0.1M Sodium bicarbonate buffer, pH 8.2 with 0.02% Sodium Azide.
Gene Accession No.:
Q92876
Immunogen:
Recombinant full-length human Kallikrein 6.
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone E24 reacts with kallikrein-6, but not other kallikrein family members. Reactivity against kallikrein-6 spliced isoforms 2&3 reported by UniProt (Q92876) has not been determined.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
ELISA, Immunohistochemistry (Paraffin), Inhibition Assays
Clone:
E24
Conjugate:
Unconjugated
Gene:
KLK6, PRSS18, PRSS9
Host Species:
Mouse
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_002765.1
Target Species:
Human
Form:
Purified
Antigen: GABAA, γ2 subunit
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: P18507
Immunogen: GST-tagged recombinant protein corresponding to the cytoplasmic domain of human GABAA γ2 Subunit.
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: KC4-8A7
Conjugate: __
Gene: __
Host Species: Mouse
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_944494
Target Species: Bovine, Human, Mouse, Rat
Form: Purified
Antigen:
GABAA, γ2 subunit
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
P18507
Immunogen:
GST-tagged recombinant protein corresponding to the cytoplasmic domain of human GABAA γ2 Subunit.
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
KC4-8A7
Conjugate:
__
Gene:
__
Host Species:
Mouse
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_944494
Target Species:
Bovine, Human, Mouse, Rat
Form:
Purified
Antigen: phospho-Amyloid beta (Ser26)
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P05067
Immunogen: KLH-conjugated linear peptide corresponding to human amyloid beta peptide target region sequence with phosphorylated Ser26.
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 5H11C10 recognizes Aβ1-40 and Aβ1-42 peptides with phosphorylated Ser26, but not the non-phosphorylated peptides.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunofluorescence, Western Blot
Clone: 5H11C10
Conjugate: Unconjugated
Gene: APP, A4, AD1
Host Species: Mouse
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_000475
Target Species: Human
Form: Purified
Antigen:
phospho-Amyloid beta (Ser26)
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P05067
Immunogen:
KLH-conjugated linear peptide corresponding to human amyloid beta peptide target region sequence with phosphorylated Ser26.
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 5H11C10 recognizes Aβ1-40 and Aβ1-42 peptides with phosphorylated Ser26, but not the non-phosphorylated peptides.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunofluorescence, Western Blot
Clone:
5H11C10
Conjugate:
Unconjugated
Gene:
APP, A4, AD1
Host Species:
Mouse
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_000475
Target Species:
Human
Form:
Purified
Antigen: C9ORF72/C9RANT (poly-GA)
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: Q96LT7
Immunogen: Polyethylene glycol-conjugated linear peptide containing poly-GA sequence.
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: ELISA, Immunohistochemistry, Western Blot
Clone: 5E9
Conjugate: __
Gene: __
Host Species: Mouse
Quantity: 50 μL
Research Discipline: Neuroscience
Gene ID (Entrez): NP_001242983
Target Species: Human
Form: Purified
Antigen:
C9ORF72/C9RANT (poly-GA)
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
Q96LT7
Immunogen:
Polyethylene glycol-conjugated linear peptide containing poly-GA sequence.
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
ELISA, Immunohistochemistry, Western Blot
Clone:
5E9
Conjugate:
__
Gene:
__
Host Species:
Mouse
Quantity:
50 μL
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_001242983
Target Species:
Human
Form:
Purified