MABS1719

MilliporeSigma™ TMEM64, Mouse, Unlabeled, Clone: 7A2.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS1719-Each-of-1 In Stock ₹ 36,363.00

MABS1719 - Each of 1

₹ 36,363.00

In Stock

Quantity

1

Base Price: ₹ 36,363.00

GST (18%): ₹ 6,545.34

Total Price: ₹ 42,908.34

Antigen

TMEM64

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q6YI46

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human and rat TMEM64.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_001008495

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

7A2.1

Conjugate

Unconjugated

Gene

TMEM64

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

The immunogen sequence is 100% conserved between human and rat species and present in all four human spliced isoforms reported by UniProt (Q6YI46 & D3ZV19). Murine cross-reactivity is highly likely, but has not been confirmed.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG2a κ

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Description

  • Ras-related GTP-binding protein A (UniProt Q7L523; also known as Adenovirus E3 14.7 kDa-interacting protein 1, FIP-1
  • Rag A, RagA) is encoded by the RRAGA gene (Gene ID 10670) in human
  • Mammalian cells express four Rag GTPases that mediate amino acid sufficiency-dependent mTORC1 activation to support cell growth and proliferation
  • Rag GTPases assemble into heterodimers containing GTP-loaded RagA or RagB partnered with GDP-loaded RagC or RagD
  • Promoted by signal from an upstream amino acid-responsive supercomplex, the active Rag heterodimer accumulates on the cytoplasmic surface of the lysosome, where it recruits mTORC1 and initiates its activation
  • The pentameric Ragulator complex tethers Rag heterodimers to the lysosomal membrane and acts as RagA/B guanine nucleotide exchange factor (GEF), while the heterotrimeric GATOR1 complex and the heterodimeric FNIP-Folliculin complex function as RagA/B and RagC/D GTPase activating protein (GAP), respectively
  • Both lysosomal amino acid sensors, such as the multisubunit vacuolar ATPase (v-ATPase) and lysosomal amino acid transporter(s), and cytoplasmic amino acid sensors, such as the leucyl-tRNA synthetase (LeuRS), are part of the upstream amino acid-responsive supercomplex.

Compare Similar Items

Show Difference

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MilliporeSigma™

MABS1719

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Antigen:
TMEM64

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q6YI46

Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human and rat TMEM64.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001008495

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
7A2.1

Conjugate:
Unconjugated

Gene:
TMEM64

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
The immunogen sequence is 100% conserved between human and rat species and present in all four human spliced isoforms reported by UniProt (Q6YI46 & D3ZV19). Murine cross-reactivity is highly likely, but has not been confirmed.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ

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MilliporeSigma™

MABS1721

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Antigen:
Potassium Channel Kir3.4

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P48544

Immunogen:
GST-tagged human potassium channel Kir3.4 C-terminal end fragment.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_000881

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
8F4.1

Conjugate:
Unconjugated

Gene:
KCNJ5, GIRK4, LQT13

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 8F4.1 detects human potassium channel Kir3.4 by targeting an epitope within the C-terminal cytoplasmic domain.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

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Sigma Aldrich

MABS1753

clone 9E9.1, from mouse...


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Isotype:
__

Img

MilliporeSigma

MABS1753-25

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Antigen:
TC PTPase (PTPN2)

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
GST/His-tagged recombinant fragment corresponding to 79 amino acids from the C-terminal half of human T-cell protein-tyrosine phosphatase.

Quantity:
25 μg

Research Discipline:
Signaling

Gene ID (Entrez):
__

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Clone:
9E9.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 9E9.1 detects human T-cell protein-tyrosine phosphatase. It targets an epitope within 79 amino acids from the C-terminal half.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1