MABN1831MI
MilliporeSigma™ Atlastin-1, Mouse, Unlabeled, Clone: 3194,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN1831MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABN1831MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
Atlastin-1
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q8WXF7
Immunogen
Linear peptide corresponding to the N-terminal sequence of human Atlastin-1.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_056999
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
3194
Conjugate
Unconjugated
Gene
ATL1, GBP3, HSN1D, SPG3, SPG3A
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 3194 targets an N-terminal epitope present in both spliced isoforms of human Atlastin-1 reported by UniProt (Q8WXF7).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG2a κ
Related Products
Description
- Atlastin-1 (UniProt Q8WXF7; also known as Brain-specific GTP-binding protein, GBP-3, GTP-binding protein 3, Guanine nucleotide-binding protein 3, hGBP3, Spastic paraplegia 3 protein A) is encoded by the ATL1 (also known as GBP3, HSN1D, SPG3, SPG3A) gene (Gene ID 51062) in human
- Atlastin-1 is a dynamin/Mx/guanylate-binding protein superfamily member with three conserved guanylate-binding/GTPase active site motifs, P-loop (a.a
- 74-81), DxxG (a.a
- 146-149), and RD (217-218)
- Atlastin-1 is a multimeric integral membrane protein localized on ER and cis-Golgi apparatus and widely expressed in many tissues, including the smooth muscle, adrenal gland, kidney, testis, lung, and brain
- Atlastin-1 interacts with the microtubule-severing ATPase spastin as well as with the DP1/Yop1p and reticulon families of ER-shaping proteins, Atlastin-1 knockdown results in decreased number of neuronal processes and impaired axon formation in cultured cortical neurons, while atlastin-1 overexpression increases total dendrite length both in vivo and in vitro
- ALT1 gene mutations cause abnormal ER morphology and are linked to hereditary spastic paraplegias (HSPs), a genetically heterogeneous group of neurological disorders, includiing SPG3 (spastic paraplegia 3, autosomal dominan) and HSN1D (neuropathy, hereditary sensory, 1D), characterized by lower limb spasticity and weakness
- Human atlastin-1 is a 492-amino acid protein that passes through the ER membrane twice (a.a
- 450-470, 472-492), having both its N- and C-terminal ends at the cytoplasmic side (a.a
- 1-449, 493-558).
Compare Similar Items
Show Difference
Antigen: Atlastin-1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q8WXF7
Immunogen: Linear peptide corresponding to the N-terminal sequence of human Atlastin-1.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_056999
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 3194
Conjugate: Unconjugated
Gene: ATL1, GBP3, HSN1D, SPG3, SPG3A
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 3194 targets an N-terminal epitope present in both spliced isoforms of human Atlastin-1 reported by UniProt (Q8WXF7).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Atlastin-1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q8WXF7
Immunogen:
Linear peptide corresponding to the N-terminal sequence of human Atlastin-1.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_056999
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
3194
Conjugate:
Unconjugated
Gene:
ATL1, GBP3, HSN1D, SPG3, SPG3A
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 3194 targets an N-terminal epitope present in both spliced isoforms of human Atlastin-1 reported by UniProt (Q8WXF7).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: Filamin-A (Ser2152)
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: P21333
Immunogen: KLH-conjugated linear peptide corresponding to the Filamin repeat 20 of human phospho-Filamin-A (Ser2152).
Quantity: 100 μL
Research Discipline: Neuroscience
Gene ID (Entrez): NP_001447
Target Species: Human, Mouse
Form: Purified
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: PS2
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Ser2152 of human and murine Filamin-A isoform 1 (P21333-1 and Q8BTM8-1) corresponds to Ser2144 of human Filamin-A isoform 2 (P21333-2). Equivalent site is not present in murine spliced isoform 2.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG2b κ
Antigen:
Filamin-A (Ser2152)
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
P21333
Immunogen:
KLH-conjugated linear peptide corresponding to the Filamin repeat 20 of human phospho-Filamin-A (Ser2152).
Quantity:
100 μL
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_001447
Target Species:
Human, Mouse
Form:
Purified
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
PS2
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Ser2152 of human and murine Filamin-A isoform 1 (P21333-1 and Q8BTM8-1) corresponds to Ser2144 of human Filamin-A isoform 2 (P21333-2). Equivalent site is not present in murine spliced isoform 2.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG2b κ
Antigen: AGE
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: Carboxymethyl Lysine modified Keyhole Limpet Hemocyanin (KLH).
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): __
Target Species: Mouse
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: 6C7
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 6C7 specifically reacts with carboxymethyl lysine modified proteins.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
AGE
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
Carboxymethyl Lysine modified Keyhole Limpet Hemocyanin (KLH).
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
__
Target Species:
Mouse
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
6C7
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 6C7 specifically reacts with carboxymethyl lysine modified proteins.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: Neuritin (CPG15)
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: GST-tagged full-length human recombinant Neuritin.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_001265639
Target Species: Human, Rat
Form: Purified
Applications: Western Blot
Clone: A6.1
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone A6.1 detects human and rat Neuritin.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
Neuritin (CPG15)
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
GST-tagged full-length human recombinant Neuritin.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_001265639
Target Species:
Human, Rat
Form:
Purified
Applications:
Western Blot
Clone:
A6.1
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone A6.1 detects human and rat Neuritin.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ