MABC1040MI
MilliporeSigma™ MTH1, Mouse, Unlabeled, Clone: 11A3.2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC1040MI-Each-of-1 | In Stock | ₹ 41,307.51 |
MABC1040MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
MTH1
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P36639
Immunogen
GST-tagged recombinant human MTH1 C-terminal fragment.
Quantity
100 μg
Research Discipline
Apoptosis & Cancer
Gene ID (Entrez)
NP_002443
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
11A3.2
Conjugate
Unconjugated
Gene
NUDT1, MTH1
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 11A3.2 recognizes an epitope present in all four spliced isoforms of human NUDT1/MTH1 reported by UniProt (P36639).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- 7,8-dihydro-8-oxoguanine triphosphatase (EC 3.6.1.55; UniProt P36639; also known as 2-hydroxy-dATP diphosphatase, 8-oxo-dGTPase, Nucleoside diphosphate-linked moiety X motif 1, Nudix motif 1) is encoded by the NUDT1 (also known as MTH1) gene (Gene ID 4521) in human
- Human MTH1/NUDT1 is the bacterial mutT ortholog that functions as a nucleotide pool-sanitising enzyme
- MTH1/NUDT1 cleaves oxidized nucleotides such as 8-oxo-deoxyguanosinetri-phosphate (8-oxo-dGTP) and converts the triphosphates into the corresponding mono-phosphates
- The hydrolysis reaction assures that the oxidized nucleotides can no longer be recognized by DNA polymerase, thereby preventing bases mispairing and transversion mutations by avoiding their incorporation during DNA replication
- Upregulated MTH1 levels are found in cancer cells as a means to reduce 8-oxo-dGTP accumulation in the nucleotide pool due to high oxidative stress levels in these cells.
Compare Similar Items
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Antigen: MTH1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P36639
Immunogen: GST-tagged recombinant human MTH1 C-terminal fragment.
Quantity: 100 μg
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_002443
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 11A3.2
Conjugate: Unconjugated
Gene: NUDT1, MTH1
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 11A3.2 recognizes an epitope present in all four spliced isoforms of human NUDT1/MTH1 reported by UniProt (P36639).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
MTH1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P36639
Immunogen:
GST-tagged recombinant human MTH1 C-terminal fragment.
Quantity:
100 μg
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_002443
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
11A3.2
Conjugate:
Unconjugated
Gene:
NUDT1, MTH1
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 11A3.2 recognizes an epitope present in all four spliced isoforms of human NUDT1/MTH1 reported by UniProt (P36639).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Antigen: Kallistatin (PI-4)
Classification: Monoclonal
Concentration: __
Formulation: __
Gene Accession No.: NP_001275961
Immunogen: Kallistatin purified from human plasma.
Quantity: 100 μg
Research Discipline: Apoptosis and Cancer
Gene ID (Entrez): __
Target Species: Human, Mouse, Rat
Form: Purified
Applications: ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry, Western Blot
Clone: G4C10
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein A Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: Clone G4C10 is a mouse monoclonal antibody that specifically detects kallistatin.
Content And Storage: Stable for 1 year at -20°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Kallistatin (PI-4)
Classification:
Monoclonal
Concentration:
__
Formulation:
__
Gene Accession No.:
NP_001275961
Immunogen:
Kallistatin purified from human plasma.
Quantity:
100 μg
Research Discipline:
Apoptosis and Cancer
Gene ID (Entrez):
__
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry, Western Blot
Clone:
G4C10
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein A Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
Clone G4C10 is a mouse monoclonal antibody that specifically detects kallistatin.
Content And Storage:
Stable for 1 year at -20°C from date of receipt.
Isotype:
IgG1 κ
Antigen: Kallistatin (PI-4)
Classification: Monoclonal
Concentration: __
Formulation: __
Gene Accession No.: NP_001275961
Immunogen: Kallistatin purified from human plasma.
Quantity: 25 μg
Research Discipline: Apoptosis and Cancer
Gene ID (Entrez): __
Target Species: Human, Mouse, Rat
Form: Purified
Applications: ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry, Western Blot
Clone: G4C10
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein A Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: Clone G4C10 is a mouse monoclonal antibody that specifically detects kallistatin.
Content And Storage: Stable for 1 year at -20°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Kallistatin (PI-4)
Classification:
Monoclonal
Concentration:
__
Formulation:
__
Gene Accession No.:
NP_001275961
Immunogen:
Kallistatin purified from human plasma.
Quantity:
25 μg
Research Discipline:
Apoptosis and Cancer
Gene ID (Entrez):
__
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry, Western Blot
Clone:
G4C10
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein A Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
Clone G4C10 is a mouse monoclonal antibody that specifically detects kallistatin.
Content And Storage:
Stable for 1 year at -20°C from date of receipt.
Isotype:
IgG1 κ