MABC1211MI
MilliporeSigma™ Sorting Nexin-17, Mouse, Unlabeled, Clone: 4B8.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC1211MI-Each-of-1 | In Stock | ₹ 41,307.51 |
MABC1211MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
Sorting Nexin-17
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q15036
Immunogen
GST-tagged recombinant fragment from the FERM-like region of human Sorting Nexin-17.
Quantity
100 μg
Research Discipline
Apoptosis & Cancer
Gene ID (Entrez)
NP_001253989
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
4B8.1
Conjugate
Unconjugated
Gene
SNX17, KIAA0064
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 4B8.1 recognizes an internal epitope within the FERM-like region present in both spliced isoforms of human sorting nexin-17 reported by UniProt (Q15036).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG2b κ
Related Products
Description
- Sorting nexin-17 (UniProt Q15036) is encoded by the SNX17 (also known as KIAA0064) gene (Gene ID 9784) in human
- The sorting nexins (SNXs) constitute a family of adaptor proteins involved in proteins trafficking through the endosomal pathway
- Originally identified as a binding partner of the cell adhesion protein P-selectin, sorting nexin-17 (SNX17) has since been shown to mediate internalization and recycling of multiple cell surface proteins including P-selectin, amyloid precursor protein (APP), integrin β1, low density lipoprotein receptor (LDLR), LDLR related protein (Lrp1), ApoER2, and FEEL1
- All SNX proteins contain a conserved phox homology (PX) domain that mediates phosphoinositides binding in a SNX type-specific manner, as well as various scaffolding modules including SH3, BAR, and PDZ domains
- SNX17 PX domain (a.a
- 1-109) displays specificity for phosphatidylinositol 3-monophosphate, which is enriched at the cytoplasmic face of the early endosome
- SNX17 also contains a 4.1 protein/ezrin/radixin/moesin (FERM) domain (a.a
- 115-432) comprised of an ubiquitin/Ras association (RA) subdomain known as the F1 lobe (a.a
- 113-205), an F2 lobe (a.a
- 206-269) with a helical structure similar to acyl-CoA binding protein, and an F3 lobe (a.a
- 270-388) similar to the phosphotyrosine binding (PTB)/pleckstrin homology domain
- The FERM domain mediates interaction with Asn-Pro-Xaa-Tyr/Phe (NPX(Y/F) motif-containing proteins for internalization as well as interaction with adaptor proteins-containing PTB (or FERM) domains to trigger signaling events.
Compare Similar Items
Show Difference
Antigen: Sorting Nexin-17
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q15036
Immunogen: GST-tagged recombinant fragment from the FERM-like region of human Sorting Nexin-17.
Quantity: 100 μg
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_001253989
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 4B8.1
Conjugate: Unconjugated
Gene: SNX17, KIAA0064
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 4B8.1 recognizes an internal epitope within the FERM-like region present in both spliced isoforms of human sorting nexin-17 reported by UniProt (Q15036).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
Sorting Nexin-17
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q15036
Immunogen:
GST-tagged recombinant fragment from the FERM-like region of human Sorting Nexin-17.
Quantity:
100 μg
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_001253989
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
4B8.1
Conjugate:
Unconjugated
Gene:
SNX17, KIAA0064
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 4B8.1 recognizes an internal epitope within the FERM-like region present in both spliced isoforms of human sorting nexin-17 reported by UniProt (Q15036).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: RGS2
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: GST/His-tagged recombinant fragment corresponding to 82 amino acids from the N-terminal region of human Regulator of G-protein signaling 2 (RGS2).
Quantity: 25 μg
Research Discipline: Apoptosis and Cancer
Gene ID (Entrez): __
Target Species: Human, Rat
Form: Purified
Applications: Western Blot, Immunohistochemistry (Paraffin)
Clone: __
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 9D9.1 specifically detects Regulator of G-protein signaling 2 (RGS2) in human and rat cells. It targets an epitope within 82 amino acids from the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2a
Antigen:
RGS2
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
GST/His-tagged recombinant fragment corresponding to 82 amino acids from the N-terminal region of human Regulator of G-protein signaling 2 (RGS2).
Quantity:
25 μg
Research Discipline:
Apoptosis and Cancer
Gene ID (Entrez):
__
Target Species:
Human, Rat
Form:
Purified
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Clone:
__
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 9D9.1 specifically detects Regulator of G-protein signaling 2 (RGS2) in human and rat cells. It targets an epitope within 82 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2a
Antigen: Ephrin-B2
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Gene Accession No.: NP_004084
Immunogen: KLH-conjugated linear peptide corresponding to human Ephrin-B2.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Immunohistochemistry, Western Blot
Clone: 10H1.1
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Purified by ion-exchange chromatography
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgM κ
Antigen:
Ephrin-B2
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Gene Accession No.:
NP_004084
Immunogen:
KLH-conjugated linear peptide corresponding to human Ephrin-B2.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Immunohistochemistry, Western Blot
Clone:
10H1.1
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Purified by ion-exchange chromatography
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgM κ
Antigen: TRAIL/CD253
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: NP_001177871
Immunogen: GST-tagged recombinant protein corresponding to human TRAIL/CD253.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry
Clone: 6D12.2
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Antigen:
TRAIL/CD253
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
NP_001177871
Immunogen:
GST-tagged recombinant protein corresponding to human TRAIL/CD253.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry
Clone:
6D12.2
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ