MABS1161MI

MilliporeSigma™ PYCR1, Mouse, Unlabeled, Clone: 2D9.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS1161MI-Each-of-1 In Stock ₹ 38,734.72

MABS1161MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

PYCR1

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

P32322

Immunogen

GST-tagged recombinant protein corresponding to the C-terminal of human PYCR1.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_001269209

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

2D9.1

Conjugate

Unconjugated

Gene

PYCR1

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Expected to react with spliced isoforms 1 and 3, but not isoform 2, reported by UniProt P32322).

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG2b κ

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Description

  • Pyrroline-5-carboxylate reductase 1, mitochondrial (EC 1.5.1.2; UniProt P32322; also known as P5C reductase 1, P5CR 1) is encoded by the PYCR1 (also known as ARCL2B, ARCL3B) gene (Gene ID 5831) in human
  • Pyrroline-5-carboxylate (P5C) reductase (PYCR1) is a mitochondrial enzyme that utilizes NAD(P)H as cofactor and catalyzes the convertion of P5C to L-proline, as well as the coversion of δ1-piperideine-6-carboxylate (P6C) to L-pipecolic acid, both of which are intermediates in the catabolism pathway of the essential amino acid L-lysine
  • PYCR1 gene mutations are associated with the autosomal recessive disorder cutis laxa type II, menifested with premature aging features such as joint laxity and wrinkled/lax skin, as well as developmental delay.

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MilliporeSigma™

MABS1161MI

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Antigen:
PYCR1

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P32322

Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal of human PYCR1.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001269209

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
2D9.1

Conjugate:
Unconjugated

Gene:
PYCR1

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Expected to react with spliced isoforms 1 and 3, but not isoform 2, reported by UniProt P32322).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2b κ

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MilliporeSigma™

MABS1166MI

--


Antigen:
AdipoR2

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q86V24

Immunogen:
GST-tagged recombinant human AdipoR2 N-terminal fragment.

Quantity:
100 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_078827

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
4D3.2

Conjugate:
Unconjugated

Gene:
ADIPOR2, PAQR2

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 4D3.2 targets an epitope within the N-terminal cytoplasmic domain.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Img

MilliporeSigma™

MABS1182

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Antigen:
RagA/B

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q7L523

Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human/mouse/rat RagA.

Quantity:
100 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_006561

Target Species:
Human

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
1H7.1

Conjugate:
Unconjugated

Gene:
RRAGA

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 1H7.1 targets an epitope within the C-terminal end sequence highly conserved between RagA and RagB.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ

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MilliporeSigma™

MABS1183MI

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Antigen:
Periostin

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q15063

Immunogen:
GST-tagged recombinant human periostin C-terminal fragment.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_006466

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
5B2.3

Conjugate:
Unconjugated

Gene:
POSTN, OSF2

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 5B2.3 epitope lies within a region C-terminal to the FAS1 domains. Immunogen covered region is 100% present in isoforms 1 (OSF-2OS), 2 (OSF-2p1), and 5, but partially missing in spliced isoforms 3, 4 (PDL-POSTN), 6, and 7. Clone 5B2.3 immunoreactivity toward these latter isoforms is possible, but has not been confirmed.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ