MABS497MI
MilliporeSigma™ Cytochrome P450 26B1, Mouse, Unlabeled, Clone: 4B7.2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS497MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABS497MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
Cytochrome P450 26B1
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q9NR63
Immunogen
GST-tagged recombinant internal fragment from the C-terminal half of human Cytochrome P450 26B1.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_063938
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
4B7.2
Conjugate
Unconjugated
Gene
CYP26B1, CYP26A2, P450RAI2, RHFCA
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Expected to react with all three spliced isoforms of human CYP26B1 reported by UniProt (Q9NR63).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG2a κ
Related Products
Description
- Cytochrome P450 26B1 (UniProt Q9NR63; also known as Cytochrome P450 26A2, Cytochrome P450 retinoic acid-inactivating 2, Cytochrome P450, subfamily XXVIB, polypeptide 1, Cytochrome P450RAI-2, Retinoic acid-metabolizing cytochrome) is encoded by the CYP26B1 (also known as CYP26A2, P450RAI2, RHFCA) gene (Gene ID 56603) in human
- Cytochromes P450 (CYP) proteins are primarily membrane-associated oxidases located either in the inner membrane of mitochondria or in the endoplasmic reticulum
- In addition to processing endogenous substrates, CYPs also metabolize exogenous drugs and potentially toxic chemicals
- The human CYP superfamily consists of 57 genes and more than 59 pseudogenes divided into 18 families and 43 subfamilies
- The CYP26 subfamily of enzymes (CYP26A1, CYP26B1/CYP26A2, CYP26C1) are retinoic acid hydroxylases responsible for the inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid
- CYP26B1 is overexpressed in colorectal cancer (CRC) cells, high CYP26B1 expression level in CRC patients is associated with poor prognosis
- CYP26B1 mutations are found in radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA), a disease characterized by craniofacial malformations, occipital encephalocele, radiohumeral fusions, oligodactyly, advanced osseous maturation, and calvarial mineralization defects.
Compare Similar Items
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Antigen: Cytochrome P450 26B1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q9NR63
Immunogen: GST-tagged recombinant internal fragment from the C-terminal half of human Cytochrome P450 26B1.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_063938
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 4B7.2
Conjugate: Unconjugated
Gene: CYP26B1, CYP26A2, P450RAI2, RHFCA
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with all three spliced isoforms of human CYP26B1 reported by UniProt (Q9NR63).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Cytochrome P450 26B1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q9NR63
Immunogen:
GST-tagged recombinant internal fragment from the C-terminal half of human Cytochrome P450 26B1.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_063938
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
4B7.2
Conjugate:
Unconjugated
Gene:
CYP26B1, CYP26A2, P450RAI2, RHFCA
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with all three spliced isoforms of human CYP26B1 reported by UniProt (Q9NR63).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: Anoctamin-5
Classification: Monoclonal
Concentration: __
Formulation: Mouse monoclonal IgMκ in buffer containing supernatant without preservatives.
Gene Accession No.: Q75V66
Immunogen: Linear peptide corresponding to mouse Anoctamin-5 near the C-terminus.
Quantity: 200 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_998764
Target Species: Human, Mouse
Form: __
Applications: Western Blot
Clone: 5F7
Conjugate: __
Gene: __
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgM κ
Antigen:
Anoctamin-5
Classification:
Monoclonal
Concentration:
__
Formulation:
Mouse monoclonal IgMκ in buffer containing supernatant without preservatives.
Gene Accession No.:
Q75V66
Immunogen:
Linear peptide corresponding to mouse Anoctamin-5 near the C-terminus.
Quantity:
200 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_998764
Target Species:
Human, Mouse
Form:
__
Applications:
Western Blot
Clone:
5F7
Conjugate:
__
Gene:
__
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgM κ
Antigen: GOT1
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: P17174
Immunogen: GST-tagged Recombinant protein corresponding to the N-terminal region of human GOT1.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_002070
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 1F5.2
Conjugate: __
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
GOT1
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
P17174
Immunogen:
GST-tagged Recombinant protein corresponding to the N-terminal region of human GOT1.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_002070
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
1F5.2
Conjugate:
__
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: CYP7B1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: Ovalbumin-conjugated linear peptide corresponding to 9 amino acids from the C-terminal end of human 25-hydroxycholesterol 7-alpha-hydroxylase (CYP7B1).
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_004811
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: M17P3F2
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone M17P3F2 detects CYP7B1 in human cerebral cortex, testis, pancreatic cancer, and colon cancer.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 λ
Antigen:
CYP7B1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
Ovalbumin-conjugated linear peptide corresponding to 9 amino acids from the C-terminal end of human 25-hydroxycholesterol 7-alpha-hydroxylase (CYP7B1).
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_004811
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
M17P3F2
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone M17P3F2 detects CYP7B1 in human cerebral cortex, testis, pancreatic cancer, and colon cancer.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 λ