MABS1166MI
MilliporeSigma™ AdipoR2, Mouse, Unlabeled, Clone: 4D3.2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1166MI-Each-of-1 | In Stock | ₹ 52,621.11 |
MABS1166MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,621.11
GST (18%): ₹ 9,471.80
Total Price: ₹ 62,092.91
Antigen
AdipoR2
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q86V24
Immunogen
GST-tagged recombinant human AdipoR2 N-terminal fragment.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_078827
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
4D3.2
Conjugate
Unconjugated
Gene
ADIPOR2, PAQR2
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 4D3.2 targets an epitope within the N-terminal cytoplasmic domain.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Adiponectin receptor protein 2 (UniProt Q86V24; also known as Progestin and adipoQ receptor family member II) is encoded by the ADIPOR2 (also known as PAQR2) gene (Gene ID 79602) in human
- Adiponectin receptor protein 1 and 2 (AdipoR1 and AdipoR2) are receptors for adiponectin, a well knonwn anti-inflammatory adipokine highly abundant in serum
- Both AdipoR1 and AdipoR2 are reported to be ubiquitously expressed with the highest expression in skeletal muscle and liver, respectively
- Circulating adiponectin levels are reduced in obesity and type II diabetes, whereas weight loss elevates serum adiponectin
- Adiponectin deficiency in mice is reported to exacerbate metabolic dysfunction by diet-induced obesity in some studies, while adiponectin overexpression alleviates metabolic dysfunction independent of weight loss in both genetic and diet-induced animal models of obesity
- Adipor1-knockout (KO) results in increased adiposity and decreased glucose clearance in mice, whereas Adipor2-KO mice are lean and displayed improved glucose clearance
- In addition to its metabolic role, adiponectin deficiency is associated with various clinical cardiovascular disorders including myocardial infarction, peripheral artery disease, and endothelial dysfunction
- In a study of murine hind limb ischemia model, blood flow recovery after chronic hind limb ischemic surgery is similar among wild-type and AdipoR1-KO mice, while revascularization in AdipoR2-KO mice is severely attenuated
- Human AdipoR2 is a 7-transmembrane (a.a
- 148-168, 182-202, 214-234, 246-266, 274-294, 310-330, 349-369) protein with the opposite topology of G protein-coupled receptors (GPCRs), having its N-terminal end at the cytoplasmic side (a.a
- 1-147) and C-terminal end at the extracellular side (a.a
- 370-386)
- Unlike GPCRs also, adipoR1 and AdipoR2 transmembrane helices are not kinked or tilted relative to the plane of the membrane.
Compare Similar Items
Show Difference
Antigen: AdipoR2
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q86V24
Immunogen: GST-tagged recombinant human AdipoR2 N-terminal fragment.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_078827
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 4D3.2
Conjugate: Unconjugated
Gene: ADIPOR2, PAQR2
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 4D3.2 targets an epitope within the N-terminal cytoplasmic domain.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
AdipoR2
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q86V24
Immunogen:
GST-tagged recombinant human AdipoR2 N-terminal fragment.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_078827
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
4D3.2
Conjugate:
Unconjugated
Gene:
ADIPOR2, PAQR2
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 4D3.2 targets an epitope within the N-terminal cytoplasmic domain.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: RagA/B
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q7L523
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human/mouse/rat RagA.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_006561
Target Species: Human
Form: Purified
Applications: Immunocytochemistry, Western Blot
Clone: 1H7.1
Conjugate: Unconjugated
Gene: RRAGA
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 1H7.1 targets an epitope within the C-terminal end sequence highly conserved between RagA and RagB.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
RagA/B
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q7L523
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human/mouse/rat RagA.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_006561
Target Species:
Human
Form:
Purified
Applications:
Immunocytochemistry, Western Blot
Clone:
1H7.1
Conjugate:
Unconjugated
Gene:
RRAGA
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 1H7.1 targets an epitope within the C-terminal end sequence highly conserved between RagA and RagB.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: Periostin
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal antibody IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q15063
Immunogen: GST-tagged recombinant human periostin C-terminal fragment.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_006466
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 5B2.3
Conjugate: Unconjugated
Gene: POSTN, OSF2
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 5B2.3 epitope lies within a region C-terminal to the FAS1 domains. Immunogen covered region is 100% present in isoforms 1 (OSF-2OS), 2 (OSF-2p1), and 5, but partially missing in spliced isoforms 3, 4 (PDL-POSTN), 6, and 7. Clone 5B2.3 immunoreactivity toward these latter isoforms is possible, but has not been confirmed.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Periostin
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q15063
Immunogen:
GST-tagged recombinant human periostin C-terminal fragment.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_006466
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
5B2.3
Conjugate:
Unconjugated
Gene:
POSTN, OSF2
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 5B2.3 epitope lies within a region C-terminal to the FAS1 domains. Immunogen covered region is 100% present in isoforms 1 (OSF-2OS), 2 (OSF-2p1), and 5, but partially missing in spliced isoforms 3, 4 (PDL-POSTN), 6, and 7. Clone 5B2.3 immunoreactivity toward these latter isoforms is possible, but has not been confirmed.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: Glucokinase/GCK
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P35557
Immunogen: GST-tagged recombinant internal fragment from the C-terminal half of human Glucokinase/GCK.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_000153
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 9G1.2
Conjugate: Unconjugated
Gene: GCK, HHF3, MODY2
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 9G1.2 recognizes an epitope present in all three spliced isoforms of human Glucokinase/GCK reported by UniProt (P35557).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Glucokinase/GCK
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P35557
Immunogen:
GST-tagged recombinant internal fragment from the C-terminal half of human Glucokinase/GCK.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000153
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
9G1.2
Conjugate:
Unconjugated
Gene:
GCK, HHF3, MODY2
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 9G1.2 recognizes an epitope present in all three spliced isoforms of human Glucokinase/GCK reported by UniProt (P35557).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ