MABS1281
MilliporeSigma™ Itk, Mouse, Unlabeled, Clone: 2F12,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1281-Each-of-1 | In Stock | ₹ 43,200.96 |
MABS1281 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,200.96
GST (18%): ₹ 7,776.173
Total Price: ₹ 50,977.133
Antigen
Itk
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q08881
Immunogen
GST-tagged recombinant human/mouse/rat Itk N-terminal fragment.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_005537
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
2F12
Conjugate
Unconjugated
Gene
ITK, EMT, LPFS1, LYK
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 2F12 targets the N-terminal region of human, mouse, and rat Itk.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Dual specificity protein phosphatase 6 (EC 3.1.3.16; EC 3.1.3.48; UniProt Q16828; also known as Dual specificity protein phosphatase PYST1, MAP kinase phosphatase 3, Mitogen-activated protein kinase phosphatase 3, MKP-3) is encoded by the DUSP6 (also known as HH19, MKP3, PYST1) gene (Gene ID 1848) in human
- MPK-3 (DUSP6) belongs to the family of dual-specificity phosphatases (DUSPs) that mediate dephosphorylation of MAPKs on threonine/serine and tyrosine residues
- DUSP6 is upregulated in HER2+ carcinomas and is among several DUSPs thought to be involved in breast cancer metastasis
- DUSP1, DUSP4, and DUSP6 are induced during epithelial-to-mesenchymal transition (EMT) and are involved in forming and maintaining breast cancer stem cells (CSCs), DUSP1 knockdown reduces CSC formation, while DUSP4 or DUSP6 knockdown enhances CSC formation
- PKC CK2alpha is reported to phosphorylate DUSP6 and increase its dephosphatase activity
- ERK1/2, on the other hand, can phosphorylate DUSP6 to promote its proteosomal degradation.
Compare Similar Items
Show Difference
Antigen: Itk
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q08881
Immunogen: GST-tagged recombinant human/mouse/rat Itk N-terminal fragment.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_005537
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 2F12
Conjugate: Unconjugated
Gene: ITK, EMT, LPFS1, LYK
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 2F12 targets the N-terminal region of human, mouse, and rat Itk.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Itk
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q08881
Immunogen:
GST-tagged recombinant human/mouse/rat Itk N-terminal fragment.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_005537
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
2F12
Conjugate:
Unconjugated
Gene:
ITK, EMT, LPFS1, LYK
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 2F12 targets the N-terminal region of human, mouse, and rat Itk.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: phospho-GRASP65 (Thr220/Thr224)
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: His-tagged recombinant full-length wild type GRASP65 protein treated with mitotic cytosol.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): __
Target Species: Rat
Form: Purified
Applications: Western Blot, Immunocytochemistry
Clone: LX108
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone LX108 specifically recognizes GRASP65 phosphorylated on Thr220/Thr224.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
phospho-GRASP65 (Thr220/Thr224)
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
His-tagged recombinant full-length wild type GRASP65 protein treated with mitotic cytosol.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
__
Target Species:
Rat
Form:
Purified
Applications:
Western Blot, Immunocytochemistry
Clone:
LX108
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone LX108 specifically recognizes GRASP65 phosphorylated on Thr220/Thr224.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: MLN64/STARD3
Classification: Monoclonal
Concentration: __
Formulation: Mouse monoclonal IgG1κ ascites with 0.05% sodium azide.
Gene Accession No.: Q14849
Immunogen: Ovalbumin-conjugated linear peptide corresponding to human MLN64/STARD3 near the C-terminus.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001159409
Target Species: Human
Form: Ascites
Applications: Immunohistochemistry, Western Blot
Clone: 2BE-2F4
Conjugate: __
Gene: __
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG1 κ
Antigen:
MLN64/STARD3
Classification:
Monoclonal
Concentration:
__
Formulation:
Mouse monoclonal IgG1κ ascites with 0.05% sodium azide.
Gene Accession No.:
Q14849
Immunogen:
Ovalbumin-conjugated linear peptide corresponding to human MLN64/STARD3 near the C-terminus.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001159409
Target Species:
Human
Form:
Ascites
Applications:
Immunohistochemistry, Western Blot
Clone:
2BE-2F4
Conjugate:
__
Gene:
__
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__