MABS1228MI

MilliporeSigma™ ANKRD1/CARP, Mouse, Unlabeled, Clone: 12G8.2,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS1228MI-Each-of-1 In Stock ₹ 39,063.27

MABS1228MI - Each of 1

₹ 39,063.27

In Stock

Quantity

1

Base Price: ₹ 39,063.27

GST (18%): ₹ 7,031.389

Total Price: ₹ 46,094.659

Antigen

ANKRD1/CARP

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q15327

Immunogen

GST-tagged recombinant human ANKRD1/CARP fragment corresponding ankyrin repeats 4&5.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_055206

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG1 κ

Applications

Western Blot

Clone

12G8.2

Conjugate

Unconjugated

Gene

ANKRD1, C193, CARP, HA1A2

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Ankyrin repeat domain-containing protein 1 (UniProt Q15327; also known as Cardiac ankyrin repeat protein, Cytokine-inducible gene C-193 protein, Cytokine-inducible nuclear protein) is encoded by the ANKRD1 (also known as C193, CARP, HA1A2) gene (Gene ID 27063) in human
  • ANKRD1/CARP belongs to a family of conserved muscle ankyrin repeat proteins (MARPs), members of which also include ANKRD2 and diabetes ankyrin repeat protein (DARP, ANKRD23)
  • ANKRD1 is highly expressed in cardiomyocytes and known to interact with myopalladin and titin, implicating its roles in myopalladin complex-dependent sarcomere integrity maintenance and stress-induced gene regulations medidated by the titin complex
  • ANKRD1 is up-regulated in patients with dilated cardiomyopathy and in animal models of cardiac hypertrophy induced by pressure overload and adrenergic stimulation
  • ANKRD1 is shown to regulate the hypertrophic agonist phenylephrine-/PE-induced α-adrenergic signaling pathway in neonatal rat ventricular myocytes, where it recruits and localizes ERK1/2 and GATA4 in a sarcomeric complex, resulting in enhanced GATA4 phosphorylation and subsequent ANKRD1 complex nuclear translocation and gene activation.

Compare Similar Items

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MilliporeSigma™

MABS1228MI

--


Antigen:
ANKRD1/CARP

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q15327

Immunogen:
GST-tagged recombinant human ANKRD1/CARP fragment corresponding ankyrin repeats 4&5.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_055206

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
12G8.2

Conjugate:
Unconjugated

Gene:
ANKRD1, C193, CARP, HA1A2

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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MilliporeSigma™

MABS1229

--


Antigen:
SKP1

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
P63208

Immunogen:
GST-tagged recombinant human SKP1 internal fragment.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_008861

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ

Applications:
Immunocytochemistry, Western Blot

Clone:
3F3.1

Conjugate:
__

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified

Img

MilliporeSigma™

MABS1234MI

--


Antigen:
Progesterone Receptor B

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
P06401

Immunogen:
Recombinant protein corresponding to the N-terminal of human Progesterone Receptor B.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_000917

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
250/H11

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

MABS1235MI

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Antigen:
Progesterone Receptor A/B

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
P06401

Immunogen:
Recombinant protein corresponding to the N-terminal half fragment of human Progesterone Receptor B.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001189403 and NP_000917

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
488/H3

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified