MABS1198MI

MilliporeSigma™ SPINK1, Mouse, Unlabeled, Clone: 4D11.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS1198MI-Each-of-1 In Stock ₹ 41,307.51

MABS1198MI - Each of 1

₹ 41,307.51

In Stock

Quantity

1

Base Price: ₹ 41,307.51

GST (18%): ₹ 7,435.352

Total Price: ₹ 48,742.862

Antigen

SPINK1

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse monoclonal IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

P00995

Immunogen

GST-tagged recombinant human SPINK1.

Quantity

100 μL

Research Discipline

Signaling

Gene ID (Entrez)

NP_003113

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

4D11.1

Conjugate

Unconjugated

Gene

SPINK1, PCTT, PSTI, TCP

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Expected to react with both pro- and mature human SPINK1.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Serine protease inhibitor Kazal-type 1 (UniProt P00995; also known as Pancreatic secretory trypsin inhibitor, TATI, Tumor-associated trypsin inhibitor) is encoded by the SPINK1 (also known as PCTT, PSTI, TCP) gene (Gene ID 6690) in human
  • Serine protease inhibitor Kazal-type 1 encoded by the human SPINK1 gene functions as an acute-phase protein (APP) in the pancreas
  • Produced initially in a 79-a.a
  • proform, the signal peptide (a.a
  • 1-23) is removed posttranslationally to yield the 56-a.a
  • (a.a
  • 24-79) mature protein
  • SPINK1 protein blocks premature activation of trypsinogen (inactive form of trypsin), thereby ensuring the integrity of acinar cells to prevent auto-digestion of the pancreas
  • SPINK1 is also reported to play a role in tissue repair, apoptosis, reproduction, and behave as a growth factor in other human organs
  • In addition, SPINK1 protein is known as tumor-associated trypsin inhibitor or TATI and current research activities are focused on the association of various cancers to deregulated SPINK1 activity.

Compare Similar Items

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Img

MilliporeSigma™

MABS1198MI

--


Antigen:
SPINK1

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P00995

Immunogen:
GST-tagged recombinant human SPINK1.

Quantity:
100 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_003113

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
4D11.1

Conjugate:
Unconjugated

Gene:
SPINK1, PCTT, PSTI, TCP

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Expected to react with both pro- and mature human SPINK1.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Img

MilliporeSigma™

MABS1208MI

--


Antigen:
LDL Receptor

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P01130

Immunogen:
GST-tagged recombinant human LDL receptor extracellular fragment corresponding to class A domains 1-3.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_000518

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
2H7.1

Conjugate:
Unconjugated

Gene:
LDLR, FH, FHC

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Expected to react with spliced isoforms 1 and 5 reported by UniProt P01130). Reactivity toward spliced isoforms 2, 3, 4, and 6 has not been determined.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2b κ

Img

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MABS1212MI

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Antigen:
Geminin

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
O75496

Immunogen:
GST-tagged recombinant human geminin internal fragment.

Quantity:
100 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001238918

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
4B10.1

Conjugate:
Unconjugated

Gene:
GMNN

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 4B10.1 detects human geminin by targeting an internal epitope.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ

Img

MilliporeSigma™

MABS1215MI

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Antigen:
Calpain I/II, large subunit

Classification:
Monoclonal

Concentration:
__

Formulation:
Mouse monoclonal IgG2aκ ascites with 0.05% sodium azide.

Gene Accession No.:
P07384

Immunogen:
Purified m-calpain from rabbit skeletal muscle.

Quantity:
50 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001185797

Target Species:
Chicken, Human, Monkey, Rabbit, Rat

Form:
Ascites

Applications:
Immunocytochemistry, Western Blot

Clone:
1D10A7

Conjugate:
__

Gene:
__

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype:
IgG2a κ