MABS1215MI
MilliporeSigma™ Mouse anti-Calpain I/II, large subunit, Clone: 1D10A7,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1215MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABS1215MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
Calpain I/II, large subunit
Classification
Monoclonal
Formulation
Mouse monoclonal IgG2aκ ascites with 0.05% sodium azide.
Gene Symbols
CAPN1; CANPL1; PIG30
Immunogen
Purified m-calpain from rabbit skeletal muscle.
Quantity
50 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_001185797
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype
IgG2a κ
Applications
Immunocytochemistry, Western Blot
Clone
1D10A7
Gene Accession No.
P07384
Host Species
Mouse
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Chicken, Human, Monkey, Rabbit, Rat
Form
Ascites
Related Products
Description
- Specifically detects Calpain I/II, large subunit clone: 1D10A7 in Chicken, Human, Monkey, Rabbit, Rat samples, and it is validated for Immunocytochemistry, Western Blotting Calpains I & II are intracellular cysteine proteinases distributed in various tissues and cells
- Calpain I & II are also known as mu- and m-calpains, respectively, based on their calcium requirement, with calpain I being active at micromolar Ca 2+ concentrations and calpain II at millimolar Ca 2+ concentrations
- Both calpains are composed of a large catalytic (80kDa) and a small regulatory (30kDa) subunit, and each subunit contains a calmodulinlike domain at the C-terminus
- Upon Ca 2+ binding to the calmodulin-like domains, calpains become activated for catalyzing both substrate proteolytic degradation as well as autolysis
- Fourteen calpain large subunits have been identified in human (calpain 1-3 & 5-15 encoded by CAPN1-3 & 5-15 gene) and two small subunits encoded by the CAPNS1 & CAPSN2 genes
- The calpain small subunit 1 encoded by CAPNS1 is also known as calpain 4
- To date, calpain I & II remain the best characterized members of the calpain family
- Calpain activity was initially characterized as 'calcium-activated neutral protease' (CANP) detected in brain, lens of the eye, and other tissues
- The name 'calpain' was later adopted as a hybrid name from two well-known proteins at the time, calmodulin and papain.
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Antigen: Calpain I/II, large subunit
Classification: Monoclonal
Formulation: Mouse monoclonal IgG2aκ ascites with 0.05% sodium azide.
Gene Symbols: CAPN1; CANPL1; PIG30
Immunogen: Purified m-calpain from rabbit skeletal muscle.
Quantity: 50 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001185797
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG2a κ
Applications: Immunocytochemistry, Western Blot
Clone: 1D10A7
Gene Accession No.: P07384
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Chicken, Human, Monkey, Rabbit, Rat
Form: Ascites
Antigen:
Calpain I/II, large subunit
Classification:
Monoclonal
Formulation:
Mouse monoclonal IgG2aκ ascites with 0.05% sodium azide.
Gene Symbols:
CAPN1; CANPL1; PIG30
Immunogen:
Purified m-calpain from rabbit skeletal muscle.
Quantity:
50 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001185797
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Western Blot
Clone:
1D10A7
Gene Accession No.:
P07384
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Chicken, Human, Monkey, Rabbit, Rat
Form:
Ascites
Antigen: MAN1B1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: MAN1B1
Immunogen: GST-tagged recombinant protein corresponding to human MAN1B1.
Quantity: 200 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_057303
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 1D6
Gene Accession No.: Q9UKM7
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Rat
Form: Purified
Antigen:
MAN1B1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
MAN1B1
Immunogen:
GST-tagged recombinant protein corresponding to human MAN1B1.
Quantity:
200 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_057303
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
1D6
Gene Accession No.:
Q9UKM7
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Rat
Form:
Purified
Antigen: SUMO-1
Classification: Monoclonal
Formulation: Rat monoclonal hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant full-length human SUMO-1.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001005781
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG2a κ
Applications: Western Blot
Clone: 4D12
Gene Accession No.: P63165
Host Species: Rat
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: __
Antigen:
SUMO-1
Classification:
Monoclonal
Formulation:
Rat monoclonal hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant full-length human SUMO-1.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001005781
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG2a κ
Applications:
Western Blot
Clone:
4D12
Gene Accession No.:
P63165
Host Species:
Rat
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
__
Antigen: TXNIP
Classification: Monoclonal
Formulation: Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: Recombinant full-length human TXNIP protein.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_006463.3
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: Western Blot
Clone: JY2
Gene Accession No.: Q9H3M7
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
TXNIP
Classification:
Monoclonal
Formulation:
Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
Recombinant full-length human TXNIP protein.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_006463.3
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
JY2
Gene Accession No.:
Q9H3M7
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified