MABS1758MI

MilliporeSigma™ RAD9A, Mouse, Unlabeled, Clone: 5H8.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS1758MI-Each-of-1 In Stock ₹ 40,197.80

MABS1758MI - Each of 1

₹ 40,197.80

In Stock

Quantity

1

Base Price: ₹ 40,197.80

GST (18%): ₹ 7,235.604

Total Price: ₹ 47,433.404

Antigen

RAD9A

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse IgGκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q99638

Immunogen

GST-tagged recombinant human RAD9A ABL1-interacting domain fragment.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_001230153

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

5H8.1

Conjugate

Unconjugated

Gene

RAD9A, RAD9

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 5H8.1 targeted epitope lies within RAD9A ABL1-interacting domain.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2; UniProt Q99638; also known as DNA repair exonuclease rad9 homolog A, hRAD9, Rad9-like protein) is encoded by the RAD9A (also known as RAD9A) gene (Gene ID 5883) in human
  • RAD9A is a component of the trimeric PCNA-like 9-1-1 complex (Rad9A, Rad1, and Hus1) and plays an important role in maintaining genomic integrity
  • RAD9A participates in both ATR and ATM signaling pathways-mediated cell cycle checkpoints in mitosis
  • Evidences indicate that RAD9A participates in DNA damage repair by interacting with proteins involved in base excision repair, mismatch repair and homologous recombination repair
  • RAD9A is shown to colocalize with γH2AX following DNA damage induction in an ATM-independent manner, and RAD9A inactivation delays the appearance of ionizing radiation-induced γH2AX foci
  • Rad9a-knockout causes embryonic lethality in mice due to increased apoptotic activity and reduced cellular proliferation, while mice heterozygous for Rad9a are prone to spontaneous and radiation-induced cataractogenesis
  • In addition, conditional knockout in keratinocytes causes enhanced susceptibility to carcinogen-induced skin tumors, while conditional Rad9a deletion in undifferentiated spermatogonia results in drastic effects on meiosis.

Compare Similar Items

Show Difference

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MilliporeSigma™

MABS1758MI

--


Antigen:
RAD9A

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgGκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q99638

Immunogen:
GST-tagged recombinant human RAD9A ABL1-interacting domain fragment.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001230153

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
5H8.1

Conjugate:
Unconjugated

Gene:
RAD9A, RAD9

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 5H8.1 targeted epitope lies within RAD9A ABL1-interacting domain.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

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MilliporeSigma

MABS178MI

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Antigen:
STK39

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
NP_037365

Immunogen:
GST-tagged recombinant protein corresponding to the C-terminus of human STK39.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Immunohistochemistry, Western Blot

Clone:
5H7.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C for one year

Isotype:
IgG1 κ

Img

MilliporeSigma

MABS1805-25

--


Antigen:
Dach1

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
GST/His-tagged recombinant fragment coreesponding to 60 amino acids from the C-termnal region of human Dach1.

Quantity:
25 μg

Research Discipline:
Signaling

Gene ID (Entrez):
__

Target Species:
Human, Mouse

Form:
Purified

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Clone:
1F6.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 1F6.1 detects all isoforms of Dach1 in human and murine cells. It targets an epitope within 60 amino acids from the C-terminal region.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2a κ

Img

Sigma Aldrich

MABS1805M

clone 1F6.1, from mouse...


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Isotype:
__