MABS1697MI

MilliporeSigma™ WISP-3, Mouse, Unlabeled, Clone: 13C4.1,

Manufacturer: MilliporeSigma™

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Pack Size SKU Availability Price
Each of 1 MABS1697MI-Each-of-1 In Stock ₹ 41,307.51

MABS1697MI - Each of 1

₹ 41,307.51

In Stock

Quantity

1

Base Price: ₹ 41,307.51

GST (18%): ₹ 7,435.352

Total Price: ₹ 48,742.862

Antigen

WISP-3

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

O95389

Immunogen

GST-tagged recombinant human WISP-3 IGFBP domain fragment.

Quantity

100 μL

Research Discipline

Signaling

Gene ID (Entrez)

NP_003871

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

13C4.1

Conjugate

Unconjugated

Gene

WISP3, CCN6, LIBC, PPAC, PPRD, UNQ462/PRO790/PRO956

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 13C4.1 targets an epitope within the WISP-3 IGFBP domain.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Lymphocyte cytosolic protein 2 (UniProt: Q13094; also known as Lymphocyte cytosolic protein 2, SH2 domain-containing leukocyte protein of 76 kDa, SLP-76 tyrosine phosphoprotein, SLP76) is encoded by the gene LCP2 (Gene ID 3937) in human
  • SLP-76 is a cytoplasmic adaptor phosphoprotein that contains both SH2 and SAM domains and is involved in B and T cell receptor signaling
  • Its amino terminus contains an acidic region that includes a PEST domain and several tyrosine residues that are phosphorylated following TCR ligation
  • SLP-76 also contains a central proline-rich domain and a SH2 domain at its carboxy terminal
  • SLP-76 can be phosphorylated on multiple tyrosine residues by the upstream kinases ZAP-70 and Lck
  • SLP-76 phosphorylation plays an important role in T cell-mediated IL-2 production by allowing phosphorylated Vav to bind and this complex stimulates NFAT and IL-2 gene activation after TCR engagement
  • SLP-76 is highly expressed in spleen, thymus, and peripheral blood leukocytes and T cells
  • It is expressed in B cell lines at lower levels and is not detected in fibroblast and neuroblastoma cell lines
  • SLP-76 is reported to play a positive role in promoting T cell development and activation as well as mast cell and platelet function
  • Overexpression of SLP-76 is shown to enhance IL-2 transcription after TCR signaling.

Compare Similar Items

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MilliporeSigma™

MABS1697MI

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Antigen:
WISP-3

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
O95389

Immunogen:
GST-tagged recombinant human WISP-3 IGFBP domain fragment.

Quantity:
100 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_003871

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
13C4.1

Conjugate:
Unconjugated

Gene:
WISP3, CCN6, LIBC, PPAC, PPRD, UNQ462/PRO790/PRO956

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 13C4.1 targets an epitope within the WISP-3 IGFBP domain.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

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MilliporeSigma™

MABS1704MI

--


Antigen:
Potassium Channel Kir6.2

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q14654

Immunogen:
KLH-conjugated linear peptide corresponding an N-terminal cytoplasmic domain sequence of human potassium channel Kir6.2.

Quantity:
100 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001159762

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
10C1.1

Conjugate:
Unconjugated

Gene:
KCNJ11, BIR, HHF2, MODY13, PNDM, TNDM3

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 10C1.1 targets human Kir6.2 N-terminal cytoplasmic region not present in the alternatively spliced isoform 2.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Img

Sigma Aldrich

MABS1708

clone 3A1.1, from mouse...


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Isotype:
__

Img

MilliporeSigma

MABS1708-25

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Antigen:
SAV1

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
GST/His-tagged recombinant fragment corresponding to 101 amino acids from the C-terminal half of human Protein salvador homolog 1 (SAV1).

Quantity:
25 μg

Research Discipline:
Signaling

Gene ID (Entrez):
__

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Clone:
3A1.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 3A1.1 detects Protein salvador homolog 1 in human cells It targets an epitope with in 101 amino acids from the C-terminal half.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2a κ