MABS1182
MilliporeSigma™ RagA/B, Mouse, Unlabeled, Clone: 1H7.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1182-Each-of-1 | In Stock | ₹ 42,677.33 |
MABS1182 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,677.33
GST (18%): ₹ 7,681.919
Total Price: ₹ 50,359.249
Antigen
RagA/B
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q7L523
Immunogen
KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human/mouse/rat RagA.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_006561
Target Species
Human
Form
Purified
Applications
Immunocytochemistry, Western Blot
Clone
1H7.1
Conjugate
Unconjugated
Gene
RRAGA
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 1H7.1 targets an epitope within the C-terminal end sequence highly conserved between RagA and RagB.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG2a κ
Related Products
Description
- Ras-related GTP-binding protein A (UniProt Q7L523; also known as Adenovirus E3 14.7 kDa-interacting protein 1, FIP-1
- Rag A, RagA) is encoded by the RRAGA gene (Gene ID 10670) in human
- Mammalian cells express four Rag GTPases that mediate amino acid sufficiency-dependent mTORC1 activation to support cell growth and proliferation
- Rag GTPases assemble into heterodimers containing GTP-loaded RagA or RagB partnered with GDP-loaded RagC or RagD
- Promoted by signal from an upstream amino acid-responsive supercomplex, the active Rag heterodimer accumulates on the cytoplasmic surface of the lysosome, where it recruits mTORC1 and initiates its activation
- The pentameric Ragulator complex tethers Rag heterodimers to the lysosomal membrane and acts as RagA/B guanine nucleotide exchange factor (GEF), while the heterotrimeric GATOR1 complex and the heterodimeric FNIP-Folliculin complex function as RagA/B and RagC/D GTPase activating protein (GAP), respectively
- Both lysosomal amino acid sensors, such as the multisubunit vacuolar ATPase (v-ATPase) and lysosomal amino acid transporter(s), and cytoplasmic amino acid sensors, such as the leucyl-tRNA synthetase (LeuRS), are part of the upstream amino acid-responsive supercomplex.
Compare Similar Items
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Antigen: RagA/B
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q7L523
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human/mouse/rat RagA.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_006561
Target Species: Human
Form: Purified
Applications: Immunocytochemistry, Western Blot
Clone: 1H7.1
Conjugate: Unconjugated
Gene: RRAGA
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 1H7.1 targets an epitope within the C-terminal end sequence highly conserved between RagA and RagB.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
RagA/B
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q7L523
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human/mouse/rat RagA.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_006561
Target Species:
Human
Form:
Purified
Applications:
Immunocytochemistry, Western Blot
Clone:
1H7.1
Conjugate:
Unconjugated
Gene:
RRAGA
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 1H7.1 targets an epitope within the C-terminal end sequence highly conserved between RagA and RagB.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: Periostin
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal antibody IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q15063
Immunogen: GST-tagged recombinant human periostin C-terminal fragment.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_006466
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 5B2.3
Conjugate: Unconjugated
Gene: POSTN, OSF2
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 5B2.3 epitope lies within a region C-terminal to the FAS1 domains. Immunogen covered region is 100% present in isoforms 1 (OSF-2OS), 2 (OSF-2p1), and 5, but partially missing in spliced isoforms 3, 4 (PDL-POSTN), 6, and 7. Clone 5B2.3 immunoreactivity toward these latter isoforms is possible, but has not been confirmed.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Periostin
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q15063
Immunogen:
GST-tagged recombinant human periostin C-terminal fragment.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_006466
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
5B2.3
Conjugate:
Unconjugated
Gene:
POSTN, OSF2
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 5B2.3 epitope lies within a region C-terminal to the FAS1 domains. Immunogen covered region is 100% present in isoforms 1 (OSF-2OS), 2 (OSF-2p1), and 5, but partially missing in spliced isoforms 3, 4 (PDL-POSTN), 6, and 7. Clone 5B2.3 immunoreactivity toward these latter isoforms is possible, but has not been confirmed.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: Glucokinase/GCK
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P35557
Immunogen: GST-tagged recombinant internal fragment from the C-terminal half of human Glucokinase/GCK.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_000153
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 9G1.2
Conjugate: Unconjugated
Gene: GCK, HHF3, MODY2
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 9G1.2 recognizes an epitope present in all three spliced isoforms of human Glucokinase/GCK reported by UniProt (P35557).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Glucokinase/GCK
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P35557
Immunogen:
GST-tagged recombinant internal fragment from the C-terminal half of human Glucokinase/GCK.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000153
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
9G1.2
Conjugate:
Unconjugated
Gene:
GCK, HHF3, MODY2
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 9G1.2 recognizes an epitope present in all three spliced isoforms of human Glucokinase/GCK reported by UniProt (P35557).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: ABCB11
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: O95342
Immunogen: GST-tagged recombinant fragment derived from the fourth cytoplasmic domain of human ABCB11.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_003733
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 10D4.1
Conjugate: __
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
ABCB11
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
O95342
Immunogen:
GST-tagged recombinant fragment derived from the fourth cytoplasmic domain of human ABCB11.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003733
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
10D4.1
Conjugate:
__
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ