MABS1193
MilliporeSigma™ Mouse anti-ABCB11, Clone: 10D4.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1193-Each-of-1 | In Stock | ₹ 38,734.72 |
MABS1193 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
ABCB11
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
ABCB11; BRIC2; BSEP; PFIC2; SPGP
Immunogen
GST-tagged recombinant fragment derived from the fourth cytoplasmic domain of human ABCB11.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_003733
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG1 κ
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
10D4.1
Gene Accession No.
O95342
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects ABCB11 clone: 10D4.1 in Human samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting Bile salt export pump (UniProt O95342; also known as ATP-binding cassette sub-family B member 11, Sister of P-glycoprotein) is encoded by the ABCB11 (also known as BRIC2, BSEP, PFIC2, SPGP) gene (Gene ID 8647) in human
- Bile is produced by hepatocytes in the liver and released into the biliary system of ducts and gallbladder
- After food ingestion, bile is released in the form of mixed micelles of salts and phospholipids into the duodenum where its detergent properties act to solubilize lipids to help their absorption by the intestine
- Bile salt export pump is an ATP-binding cassette (ABC) family member localized to the hepatocyte canalicular membrane where it plays an important role in the bile salt-dependent bile flow and the normal enterohepatic circulation of bile salts from the distal intestine back to the liver
- ABCB11/BSEP gene mutations are associated with progressive familial intrahepatic cholestasis type 2 (PFIC2), benign recurrent intrahepatic cholestasis type 2 (BRIC2), drug-induced cholestasis, hormone-dependent intrahepatic cholestasis of pregnancy (ICP), biliary lithiasis, and transient neonatal cholestasis, as a result of impaired bile flow
- Bile salt export pump is a 12-transmembrane protein (a.a
- 63-83, 148-168, 216-236, 241-261, 320-340, 354-374, 756-776, 795-815, 870-890, 891-911, 980-1000, 1012-1032) with both its N- and C-terminal ends exposed cyroplasmically (a.a
- 1-62 and 1033-1321).
Compare Similar Items
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Antigen: ABCB11
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: ABCB11; BRIC2; BSEP; PFIC2; SPGP
Immunogen: GST-tagged recombinant fragment derived from the fourth cytoplasmic domain of human ABCB11.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_003733
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 10D4.1
Gene Accession No.: O95342
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
ABCB11
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
ABCB11; BRIC2; BSEP; PFIC2; SPGP
Immunogen:
GST-tagged recombinant fragment derived from the fourth cytoplasmic domain of human ABCB11.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003733
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
10D4.1
Gene Accession No.:
O95342
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: SSH1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: SSH1; KIAA1298; SSH1L
Immunogen: GST-tagged recombinant protein corresponding to an internal sequence of human SSH1.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_061857
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: Western Blot
Clone: 12C6.1
Gene Accession No.: Q8WYL5
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
SSH1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
SSH1; KIAA1298; SSH1L
Immunogen:
GST-tagged recombinant protein corresponding to an internal sequence of human SSH1.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_061857
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Western Blot
Clone:
12C6.1
Gene Accession No.:
Q8WYL5
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: SENP1
Classification: Monoclonal
Formulation: Mouse monoclonal IgG2bλ hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant fragment from the C-terminal half of human SENP1.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001254523
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG2b λ
Applications: Western Blot
Clone: 8B6.1
Gene Accession No.: Q9P0U3
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Culture Supernatant
Antigen:
SENP1
Classification:
Monoclonal
Formulation:
Mouse monoclonal IgG2bλ hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant fragment from the C-terminal half of human SENP1.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001254523
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG2b λ
Applications:
Western Blot
Clone:
8B6.1
Gene Accession No.:
Q9P0U3
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Culture Supernatant
Antigen: SPINK1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant human SPINK1.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_003113
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: Western Blot
Clone: 4D11.1
Gene Accession No.: P00995
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
SPINK1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant human SPINK1.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003113
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
4D11.1
Gene Accession No.:
P00995
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified