MABS1196MI
MilliporeSigma™ SENP1, Mouse, Unlabeled, Clone: 8B6.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1196MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABS1196MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
SENP1
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Mouse monoclonal IgG2bλ hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Accession No.
Q9P0U3
Immunogen
GST-tagged recombinant fragment from the C-terminal half of human SENP1.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_001254523
Target Species
Human
Form
Culture Supernatant
Applications
Western Blot
Clone
8B6.1
Conjugate
Unconjugated
Gene
SENP1
Host Species
Mouse
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Expected to react with both spliced isoforms of human SENP1 reported by UniProt (Q9P0U3).
Content And Storage
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype
IgG2b λ
Related Products
Description
- Sentrin-specific protease 1 (EC 3.4.22.68; UniProt Q9P0U3; also known as Sentrin/SUMO-specific protease SENP1) is encoded by the SENP1 gene (Gene ID 29843) in human
- SUMOylation, protein posttranslation modification by small ubiquitin-like modifier (SUMO), is a signaling event in many cellular processes
- As is the case with ubiquitination, SUMOylation is a reversible process
- SUMO E1 activating enzyme, E2 conjugating enzyme, and E3 ligase mediate SUMOylation of substrate proteins, while a family of SUMO-specific proteases (SENPs) are responsible for the deSUMOylation
- Seven SENPs are identified in human (SENP1-3 and SENP5-8)
- SENP1 processes full-length SUMO1, SUMO2 and SUMO3 to their mature forms and mediates their removal (deconjugation) from substrate proteins, including BHLHE40/DEC1, CCAR2, CLOCK, DBC1, HADC1, HIPK2, MTA1, p53, and SIRT1
- SENP1 is reported to be overexpressed and induced by IL-6 in multiple myeloma (MM) cells, and SENP1-knockdown triggers apoptosis and reduces viability, proliferation and colony forming ability of MM cells.
Compare Similar Items
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Antigen: SENP1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Mouse monoclonal IgG2bλ hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Accession No.: Q9P0U3
Immunogen: GST-tagged recombinant fragment from the C-terminal half of human SENP1.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001254523
Target Species: Human
Form: Culture Supernatant
Applications: Western Blot
Clone: 8B6.1
Conjugate: Unconjugated
Gene: SENP1
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with both spliced isoforms of human SENP1 reported by UniProt (Q9P0U3).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG2b λ
Antigen:
SENP1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Mouse monoclonal IgG2bλ hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Accession No.:
Q9P0U3
Immunogen:
GST-tagged recombinant fragment from the C-terminal half of human SENP1.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001254523
Target Species:
Human
Form:
Culture Supernatant
Applications:
Western Blot
Clone:
8B6.1
Conjugate:
Unconjugated
Gene:
SENP1
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with both spliced isoforms of human SENP1 reported by UniProt (Q9P0U3).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG2b λ
Antigen: SPINK1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P00995
Immunogen: GST-tagged recombinant human SPINK1.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_003113
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 4D11.1
Conjugate: Unconjugated
Gene: SPINK1, PCTT, PSTI, TCP
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with both pro- and mature human SPINK1.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
SPINK1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P00995
Immunogen:
GST-tagged recombinant human SPINK1.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003113
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
4D11.1
Conjugate:
Unconjugated
Gene:
SPINK1, PCTT, PSTI, TCP
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with both pro- and mature human SPINK1.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: LDL Receptor
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P01130
Immunogen: GST-tagged recombinant human LDL receptor extracellular fragment corresponding to class A domains 1-3.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_000518
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 2H7.1
Conjugate: Unconjugated
Gene: LDLR, FH, FHC
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with spliced isoforms 1 and 5 reported by UniProt P01130). Reactivity toward spliced isoforms 2, 3, 4, and 6 has not been determined.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
LDL Receptor
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P01130
Immunogen:
GST-tagged recombinant human LDL receptor extracellular fragment corresponding to class A domains 1-3.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000518
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
2H7.1
Conjugate:
Unconjugated
Gene:
LDLR, FH, FHC
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with spliced isoforms 1 and 5 reported by UniProt P01130). Reactivity toward spliced isoforms 2, 3, 4, and 6 has not been determined.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: Geminin
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: O75496
Immunogen: GST-tagged recombinant human geminin internal fragment.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001238918
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 4B10.1
Conjugate: Unconjugated
Gene: GMNN
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 4B10.1 detects human geminin by targeting an internal epitope.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Geminin
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
O75496
Immunogen:
GST-tagged recombinant human geminin internal fragment.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001238918
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
4B10.1
Conjugate:
Unconjugated
Gene:
GMNN
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 4B10.1 detects human geminin by targeting an internal epitope.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ