MABC616MI
MilliporeSigma™ NOX4, Mouse, Unlabeled, Clone: 10A8.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC616MI-Each-of-1 | In Stock | ₹ 41,307.51 |
MABC616MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
NOX4
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Mouse monoclonal IgG2bκ hybridoma culture supernatant without preservatives.
Gene Accession No.
Q9NPH5
Immunogen
GST-tagged recombinant protein corresponding to a fragment from the third extracellular loop of human NOX4.
Quantity
100 μL
Research Discipline
Apoptosis & Cancer
Gene ID (Entrez)
NP_001137308
Target Species
Human
Form
Culture Supernatant
Applications
Western Blot
Clone
10A8.1
Conjugate
Unconjugated
Gene
NOX4, RENOX
Host Species
Mouse
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Immunogen construct region is present in human NOX4 spliced isoform 1, 2 (Nox4A), and 8, missing in isoform 5 (Nox4C), 7, and 9, partially truncated in isoform 3 (Nox4E), 4 (Nox4D), and 6 (Nox4B) reported by UniProt (Q9NPH5).
Content And Storage
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype
IgG2b κ
Related Products
Description
- NADPH oxidase 4 (UniProt Q9NPH5; also known as Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX-1, Renal NAD(P)H-oxidase) is encoded by the NOX4 (also known as RENOX) gene (Gene ID 50507) in human
- NOX4 belongs to the family of NADPH oxidases that modulate redox-dependent cellular signalling pathways via intracellular reactive oxygen species (ROS) generation
- Seven family members have been identified in mammals (NOX1–5 and DUOX1/2) with member-specific cellular distribution, intracellular location, mechanisms of action and types of ROS produced
- NOX4 produces predominantly H2O2, and is widely expressed in many cell types and adult tissues, including kidney, liver, heart and aorta
- NOX4 plays an important role in homocysteine (Hcy) metabolism, which in turns is a determining factor that impacts on defence against environmental toxins
- Nox-knocout in mice results in significantly decreased total plasma Hcy levels, causing markedly increased susceptibility to acetaminophen- (APAP-, paracetamol-) induced hepatoxicity as a result of significantly decreased cysteine production and hepatic GSH stores
- Human NOX4 is a six-transmembrane (a.a
- 17-37, 63-83, 104-124, 155-175, 189-209, 425-445) protein, having both its N- and C-terminal ends at the cytoplasmic side (a.a
- 1-16 and 446-578).
Compare Similar Items
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Antigen: NOX4
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Mouse monoclonal IgG2bκ hybridoma culture supernatant without preservatives.
Gene Accession No.: Q9NPH5
Immunogen: GST-tagged recombinant protein corresponding to a fragment from the third extracellular loop of human NOX4.
Quantity: 100 μL
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_001137308
Target Species: Human
Form: Culture Supernatant
Applications: Western Blot
Clone: 10A8.1
Conjugate: Unconjugated
Gene: NOX4, RENOX
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Immunogen construct region is present in human NOX4 spliced isoform 1, 2 (Nox4A), and 8, missing in isoform 5 (Nox4C), 7, and 9, partially truncated in isoform 3 (Nox4E), 4 (Nox4D), and 6 (Nox4B) reported by UniProt (Q9NPH5).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG2b κ
Antigen:
NOX4
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Mouse monoclonal IgG2bκ hybridoma culture supernatant without preservatives.
Gene Accession No.:
Q9NPH5
Immunogen:
GST-tagged recombinant protein corresponding to a fragment from the third extracellular loop of human NOX4.
Quantity:
100 μL
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_001137308
Target Species:
Human
Form:
Culture Supernatant
Applications:
Western Blot
Clone:
10A8.1
Conjugate:
Unconjugated
Gene:
NOX4, RENOX
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Immunogen construct region is present in human NOX4 spliced isoform 1, 2 (Nox4A), and 8, missing in isoform 5 (Nox4C), 7, and 9, partially truncated in isoform 3 (Nox4E), 4 (Nox4D), and 6 (Nox4B) reported by UniProt (Q9NPH5).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG2b κ
Antigen: KLF4
Classification: Monoclonal
Concentration: __
Formulation: Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.: NP_004226
Immunogen: Purified recombinant fragment of human KLF4 expressed in E. coli.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Ascites
Applications: Immunohistochemistry, Western Blot
Clone: 1E06
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG1
Antigen:
KLF4
Classification:
Monoclonal
Concentration:
__
Formulation:
Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.:
NP_004226
Immunogen:
Purified recombinant fragment of human KLF4 expressed in E. coli.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Ascites
Applications:
Immunohistochemistry, Western Blot
Clone:
1E06
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG1
Antigen: MUM1
Classification: Monoclonal
Concentration: __
Formulation: Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.: __
Immunogen: Purified recombinant fragment of human MUM1 expressed in E. Coli.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Ascites
Applications: Immunohistochemistry, Western Blot
Clone: 4G10
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG1
Antigen:
MUM1
Classification:
Monoclonal
Concentration:
__
Formulation:
Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Accession No.:
__
Immunogen:
Purified recombinant fragment of human MUM1 expressed in E. Coli.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Ascites
Applications:
Immunohistochemistry, Western Blot
Clone:
4G10
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG1
Antigen: S100A4
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P26447
Immunogen: GST-tagged recombinant human S100A4 internal fragment.
Quantity: 100 μg
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_002952
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 9D5.1
Conjugate: Unconjugated
Gene: S100A4, CAPL, MTS1, P9KA, PEL98
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 9D5.1 was raised against human S100-A4 internal fragment that shares high sequence homology with the corresponding region in mouse (96%) and rat (93%) protein.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
S100A4
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P26447
Immunogen:
GST-tagged recombinant human S100A4 internal fragment.
Quantity:
100 μg
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_002952
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
9D5.1
Conjugate:
Unconjugated
Gene:
S100A4, CAPL, MTS1, P9KA, PEL98
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 9D5.1 was raised against human S100-A4 internal fragment that shares high sequence homology with the corresponding region in mouse (96%) and rat (93%) protein.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ