MABC786MI

MilliporeSigma™ TSG101, clone 4A10, Rabbit, Unlabeled, Clone: 4A10,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABC786MI-Each-of-1 In Stock ₹ 41,643.76

MABC786MI - Each of 1

₹ 41,643.76

In Stock

Quantity

1

Base Price: ₹ 41,643.76

GST (18%): ₹ 7,495.877

Total Price: ₹ 49,139.637

Antigen

TSG101, clone 4A10

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rabbit monoclonal containing PBS, pH 7.4.

Gene Accession No.

Q99816

Immunogen

TSG101 protein expressed in E. coli.

Quantity

100 μg

Research Discipline

Apoptosis & Cancer

Target Species

Human

Isotype

IgG1

Applications

Immunohistochemistry, Western Blot

Clone

4A10

Conjugate

Unconjugated

Gene

TSG101

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

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Description

  • Tumor susceptibility gene 101 protein (TSG101), also known as ESCRT-I complex subunit TSG101, refers to a series of cytosolic protein complexes that are needed for the proper recognition and sorting of ubiquitin modified carrier proteins into the internal vesicles of the things like endosomes, and other multivesicular bodies (MVBs)
  • TSG101 binds to the ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into MVBs
  • TSG101 also mediates the association between the ESCRT-0 and ESCRT-I complex in the passage of ubiquitin cargo proteins along the chain of ESCRTs
  • TSG101 interacts with a protein called stathmin, a cytoplasmic phosphoprotein that is implicated in tumorigenesis, and normal TSG101 appears to act as a negative regulator of growth, genetic stability and cell cycle regulation
  • Mutations and alternatively spliced mutants are associated with breast and other cancers suggesting that defects in TSG101 assist in tumorigenesis and progression.

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MilliporeSigma™

MABC786MI

--


Antigen:
TSG101, clone 4A10

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit monoclonal containing PBS, pH 7.4.

Gene Accession No.:
Q99816

Immunogen:
TSG101 protein expressed in E. coli.

Quantity:
100 μg

Research Discipline:
Apoptosis & Cancer

Target Species:
Human

Isotype:
IgG1

Applications:
Immunohistochemistry, Western Blot

Clone:
4A10

Conjugate:
Unconjugated

Gene:
TSG101

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

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MilliporeSigma

MABC82MI

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Antigen:
RIP1/RIPK1

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
NP_003795

Immunogen:
GST-tagged recombinant protein corresponding to human RIP1/RIPK1.

Quantity:
100 μg

Research Discipline:
__

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Western Blot

Clone:
3C6.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Content And Storage:
2-8°C for one year

Img

MilliporeSigma

MABC83MI

--


Antigen:
Vsp4/SKD1

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
NP_004860

Immunogen:
Linear peptide corresponding to human Vps4/SKD1.

Quantity:
100 μg

Research Discipline:
__

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
5E6.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Content And Storage:
2-8°C for one year

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MilliporeSigma

MABC87MI

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Antigen:
CD148/DEP-1

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing PBS without preservatives.

Gene Accession No.:
NP_001091973

Immunogen:
His-tagged recombinant protein corresponding to Human CD148/DEP-1.

Quantity:
100 μg

Research Discipline:
__

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
Ab 1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein A purified

Regulatory Status:
__

Primary or Secondary:
Primary

Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.