MABS1154
MilliporeSigma™ Mouse anti-Derlin-1, Clone: 8G11.2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1154-Each-of-1 | In Stock | ₹ 41,307.51 |
MABS1154 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
Derlin-1
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
DERL1; DER1; UNQ243/PRO276
Immunogen
GST-tagged recombinant human derlin-1 C-terminal cytoplasmic fragment.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_001128143
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2b κ
Applications
Immunocytochemistry, Western Blot
Clone
8G11.2
Gene Accession No.
Q9BUN8
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Purified
Related Products
Description
- Specifically detects Derlin-1 clone: 8G11.2 in Human, Mouse samples, and it is validated for Immunocytochemistry, Western Blotting Derlin-1 (UniProt Q9BUN8; also known as Degradation in endoplasmic reticulum protein 1, Der1-like protein 1, DERtrin-1) is encoded by the DERL1 (also known as DER1) gene (ORF UNQ243/PRO276; Gene ID 79139) in human
- Derlins are integral ER membrane proteins that form homo-oligomers and heteromultimeric complexes with membrane-bound machinery, including the E3 ubiquitin ligase Hrd1 and its binding partner SEL1L, involved in ER-associated degradation (ERAD)
- Before ERAD substrates can be processed by the cytoplasmic ubiquitin-proteasome system, they need to be translocated across the ER membrane through an AAA ATPase p97/VCP-driven process
- Derlins are inactive members of the rhomboid family of intramembrane proteases that mediate the recruitment of AAA ATPase p97/VCP through interaction via their C-terminal SHP boxes
- Derlin-1 is proposed to contain four transmembrane segments (a.a
- 23-43, 60-80, 106-126, 155-175), three cytoplasmic domains (a.a
- 23-43, 60-80, 106-126, 155-175), and two lumenol (a.a
- 44-59 & 127-154) domains.
Compare Similar Items
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Antigen: Derlin-1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: DERL1; DER1; UNQ243/PRO276
Immunogen: GST-tagged recombinant human derlin-1 C-terminal cytoplasmic fragment.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001128143
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Applications: Immunocytochemistry, Western Blot
Clone: 8G11.2
Gene Accession No.: Q9BUN8
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Antigen:
Derlin-1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
DERL1; DER1; UNQ243/PRO276
Immunogen:
GST-tagged recombinant human derlin-1 C-terminal cytoplasmic fragment.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001128143
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Immunocytochemistry, Western Blot
Clone:
8G11.2
Gene Accession No.:
Q9BUN8
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Antigen: Fibrocystin
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: PKHD1; FCYT; TIGM1
Immunogen: Recombinant protein corresponding to human Fibrocystin fragment from the N-terminal half.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_619639
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone: 18
Gene Accession No.: P08F94
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Rat
Form: Purified
Antigen:
Fibrocystin
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
PKHD1; FCYT; TIGM1
Immunogen:
Recombinant protein corresponding to human Fibrocystin fragment from the N-terminal half.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_619639
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone:
18
Gene Accession No.:
P08F94
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Rat
Form:
Purified
Antigen: PYCR1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant protein corresponding to the C-terminal of human PYCR1.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001269209
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: 2D9.1
Gene Accession No.: P32322
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
PYCR1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal of human PYCR1.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001269209
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
2D9.1
Gene Accession No.:
P32322
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: AdipoR2
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant human AdipoR2 N-terminal fragment.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_078827
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: Western Blot
Clone: 4D3.2
Gene Accession No.: Q86V24
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
AdipoR2
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant human AdipoR2 N-terminal fragment.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_078827
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
4D3.2
Gene Accession No.:
Q86V24
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified