MABS528MI

MilliporeSigma™ Mouse anti-HGPRT, Clone: 13H11.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS528MI-Each-of-1 In Stock ₹ 38,734.72

MABS528MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

HGPRT

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

HPRT1; HPRT

Immunogen

GST-tagged human HGPRT recombinant fragment lacking N- and C-terminal regions.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_000185

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2b κ

Applications

Western Blot

Clone

13H11.1

Gene Accession No.

P00492

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects HGPRT clone: 13H11.1 in Human samples, and it is validated for Western Blotting Hypoxanthine-guanine phosphoribosyltransferase (EC:2.4.2.8; UniProt P00492; also known as HGPRT, HGPRTase) is encoded by the HPRT1 (also known as HGPRT, HPRT) gene (Gene ID 3251) in human
  • HPRT is a purine salvage enzyme that catalyzes the condensation of 5-phosphoribosyl 1-pyrophosphate (PRPP) and hypoxanthine or guanine to form inosine 5-monophosphate (IMP) and guanosine 5-monophosphate (GMP), respectively
  • PRPP is an essential compound for the de novo pathway of purine synthesis as well as the synthesis of pyrimidine compounds
  • PRPP concentrations in erythrocyte are markedly increased in individuals with HPRT deficiency
  • Complete HPRT deficiency leads to Lesch–Nyhan disease (LND) characterized by uric acid overproduction, motor dysfunction, cognitive disability, and self-injurious behavior
  • Partial deficiency of HPRT activity causes Lesch–Nyhan variant (LNV) characterized by hyperuricemia and variable degree of neurological manifestations, depending on the residual enzyme activity.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

MABS528MI

--


Antigen:
HGPRT

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
HPRT1; HPRT

Immunogen:
GST-tagged human HGPRT recombinant fragment lacking N- and C-terminal regions.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_000185

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
Western Blot

Clone:
13H11.1

Gene Accession No.:
P00492

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

MABS529MI

--


Antigen:
MEKK5

Classification:
Monoclonal

Formulation:
Purified rat monoclonal IgG2bκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Map3k5; Ask1; Mekk5

Immunogen:
Recombinant protein corresponding to the C-terminus of mouse MEKK5.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_032606

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
Western Blot

Clone:
TC003

Gene Accession No.:
O35099

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

Img

MilliporeSigma

MABS62MI

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Antigen:
GREB1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
GREB1

Immunogen:
Recombinant protein corresponding to human GREB1.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C for one year

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
GREB1Ab

Gene Accession No.:
NP_055483

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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MABS64MI

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Antigen:
phospho-p38 (Thr180/Tyr182)

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgGκ in buffer containing 0.1MTris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide.

Gene Symbols:
SAPK2a, MAPK14, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, p38ALPHA, RK, Mxi2, EXIP

Immunogen:
Linear peptide corresponding to human p38 phosphorylated at Thr180 and Tyr182.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C for one year

Isotype:
__

Applications:
Immunocytochemistry, Western Blot

Clone:
6E5.2

Gene Accession No.:
NP_001306.1

Host Species:
Mouse

Purification Method:
Protein G purfied

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified