MABC1038

MilliporeSigma™ Mouse anti-NQO2, Clone: 4A4.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABC1038-Each-of-1 In Stock ₹ 41,307.51

MABC1038 - Each of 1

₹ 41,307.51

In Stock

Quantity

1

Base Price: ₹ 41,307.51

GST (18%): ₹ 7,435.352

Total Price: ₹ 48,742.862

Antigen

NQO2

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

NQO2; NMOR2

Immunogen

GST-tagged recombinant human NQO2 N-terminal fragment.

Quantity

100 μg

Research Discipline

Apoptosis, Cancer

Gene ID (Entrez)

NP_000895

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2b κ

Applications

Immunohistochemistry, Western Blot

Clone

4A4.1

Gene Accession No.

P16083

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects NQO2 clone: 4A4.1 in Human samples, and it is validated for Immunohistochemistry, Western Blotting Ribosyldihydronicotinamide dehydrogenase [quinone] (EC 1.10.5.1; UniProt P16083; also known as NRH dehydrogenase [quinone] 2, NRH:quinone oxidoreductase 2, Quinone reductase 2, QR2) is encoded by the NQO2 (also known as NMOR2) gene (Gene ID 4835) in human
  • NQO1 (EC 1.6.5.2) and NQO2 (EC 1.10.5.1; formerly EC 1.10.99.2) constitute the quinone oxidoreductase family in human
  • NQO1 is involved in vitamin K metabolism and in reducing the cellular quinone concentration to prevent the build-up of cellular reactive oxygen species (ROS)
  • Both enzymes contain a tightly bound FAD as the oxidant cofactor, but differ in their reductant cofactors utilization
  • While NQO1 can efficiently utilize NADH or NADPH, NQO2 exhibits only low activity in the presence of NADH or NADPH
  • Instead, non-physiological compounds, such as dihydronicotinamide riboside (NRH), N-methyldihydronicotinamide, and dihydrobenzylnicotamide, are reported to act as good reductant cofactors in NQD2-catalyzed reactions in vitro
  • NQO1 & NQO2 catalyzed the reduction of a wide variety of substrates, including quinones, nitro-compounds, and iron (III) ions
  • NQO1 is inhibited by the anticoagulant dicoumarol, while NQO2 is only weakly inhibited by dicoumarol and more strongly inhibited by resveratrol.

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MABC1038

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Antigen:
NQO2

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
NQO2; NMOR2

Immunogen:
GST-tagged recombinant human NQO2 N-terminal fragment.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_000895

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
Immunohistochemistry, Western Blot

Clone:
4A4.1

Gene Accession No.:
P16083

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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Antigen:
MTH1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
GST-tagged recombinant human MTH1 C-terminal fragment.

Quantity:
100 μg

Research Discipline:
Apoptosis & Cancer

Gene ID (Entrez):
NP_002443

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Stable for 1 year at 2°-8°C from date of receipt.

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IgG1 κ

Applications:
Western Blot

Clone:
11A3.2

Gene Accession No.:
P36639

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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Formulation:
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Gene Symbols:
__

Immunogen:
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Quantity:
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Research Discipline:
__

Gene ID (Entrez):
__

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Isotype:
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Clone:
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__

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Antigen:
Kallistatin (PI-4)

Classification:
Monoclonal

Formulation:
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Gene Symbols:
SERPINA4, KST, PI4

Immunogen:
Kallistatin purified from human plasma.

Quantity:
100 μg

Research Discipline:
Apoptosis and Cancer

Gene ID (Entrez):
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Content And Storage:
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Applications:
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Host Species:
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Purification Method:
Protein A Purified

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Primary

Target Species:
Human, Mouse, Rat

Form:
Purified